Effect of electroacupuncture preconditioning on serum S100β and NSE in patients undergoing craniocerebral tumor resection

Objective：To investigate the effect of electroacupuncture preconditioning on the serum level of S100 calcium-binding protein beta（S100β）and neuron-specific enolase（NSE）in patients undergoing craniocerebral tumor operation.Methods：A total of 32 patients,who would go through craniocerebral tumor resection under general anesthesia,were randomly assigned to two groups,16 in each group.Patients in the electroacupuncture（EA）group received electroacupuncture on Fengfu acupoint（Du16）and Fengchi acupoint （GB20）for 30 min,2 h before operation.The stimulus is 1-4 mA with a density wave frequency of 2/15 Hz. Patients in the control group received no pretreatment.Anesthesia was maintained with remifentanil at the dose of 4-8 mg/kg per hour,pumped intravenous drip of vecuronium at 1.0-2.0μg/kg each hour,and discontinuous intravenous dripped with vecuronium bromide at 0.5-1 mg.The serum levels of S100βand NSE were measured with ELISA before operation,before skin incision,after tumor removal,at the end of operation,and at 24 h after operation.Results：The serum level of S100βand NSE did not change before skin incision.The serum level of NSE increased significantly and the level of S100βincreased insignificantly after the tumor resection. The serum levels of S100βand NSE in the EA group and the control group were 1.16±0.28μg/L vs 1.47±0.33μg/L,24.7±13.3μg/L vs 31.4±14.1μg/L at the end of the operation,respectively.Twenty-four h after operation,the correspondence indices were 1.18±0.31μg/L vs 1.55±0.26μg/L,and 25.5±12.4μg/L vs 32.4±11.7μg/L.The two indices at these two time points were significantly increased than those before operation, respectively（P〈0.05）.At the end of the operation and 24 h post-operation,the serum levels of S100βand NSE in the EA group were significantly lower than those in the control group（P〈0.05）.Conclusion：Electroacupuncture Fengchi and Fengfu for 30 min before craniocerbral tumor operation could decrease the serum level of S100βand NSE,thus may have potential protective effect on brain damage,which needs to befurther studied.     

X线诊断在小儿支原体肺炎的临床应用

目的探讨小儿支原体肺炎的胸部X线表现,进一步提高对支原体肺炎的诊断水平.方法回顾性分析已经确诊的60例小儿支原体肺炎的临床资料和影像学资料.结果小儿支原体肺炎在学龄期儿童(3~7岁)多见(46.7%),临床症状多以咳嗽和持续发热多见,且胸部X线征象较临床体征明显.结论小儿支原体肺炎胸部X线征象改变呈多样化,出现较早,临床结合冷凝集试验和咽拭子支原体培养PCR的阳性结果可作出快速、准确诊断.     

乌鲁木齐市大气污染与肺癌死亡关系初探

乌鲁木齐市大气污染与肺癌死亡关系初探王异，肖碧玉，贾汉，沈涛为了解乌鲁木齐市空气污染状况与肺癌死亡的关系；我们于１９９３年２～６月，对该市中心具有代表性的三个区的大气污染状况与肺癌死亡情况进行了回顾性调查。１材料与方法应用回顾性调查的方法收集１９９０...     

中西医结合治疗小儿咳嗽变异性哮喘疗效观察

目的：观察中西医结合治疗小儿咳嗽变异性哮喘的疗效。方法：230例咳嗽变异性哮喘患儿随机分为观察组和对照组各115例,对照组给予孟鲁司特钠治疗,观察组在对照组基础上采用射干麻黄汤加减治疗。观察两组咳嗽缓解和消失时间、复发情况、不良反应和临床疗效。结果：两组咳嗽缓解和消失时间、复发率、不良反应发生率和总有效率比较差异均有显著性（P〈0.05）。结论：中西医结合治疗小儿咳嗽变异性哮喘疗效显著。     

黄芪注射液治疗小儿病毒性心肌炎疗效观察

病毒性心肌炎是指由病毒及其毒素经血液循环直接侵犯心肌细胞,引起局灶性或弥漫性心肌间质炎性渗出和心肌纤维变性或坏死,导致心功能障碍和全身症状的疾病[1]。病情易迁延,常合并心包或心内膜的炎症,严重者可引起心力衰竭或心源性休     

放射免疫沉淀试验检测鼠疫FI抗体的研究——Ⅰ.特异性与敏感性

试验证明,用放射免疫沉淀试验(RIP)检测鼠疫抗体时,将被试血清与相应的阴性对照血清的结合比定为≥3作为反应标准是适宜的;用RIP检测假结核,小肠结肠炎菌等抗血清30份,这些抗血清在1:10到1:100的各种稀释度中与~(125)I-鼠疫FI抗原均无交叉反应,从非鼠疫疫区收集的2196份哺乳动物血清,亦未发现阳性反应,说明该法特异性强。由于RIP是用分离剂沉淀鼠疫抗原-抗体复合物,故能检出不完全抗体,检出率不仅高于常规的间接血球凝集试验(IHA)和酶联免疫吸附试验(ELISA),且滴度往往高十几倍、几十倍,乃至几百倍。所以用RIP检测潜在性鼠疫疫源地、考核灭源效果以及在科研中用于检测微量鼠疫抗体具有重要意义。加之该法自动化程度高,测试信息以数字显示,因而指标客观,容易分析,适于大规模现场调查。     

X线摄影在诊断先天性髋关节脱位中的临床应用

目的:探讨X线摄影在诊断先天性髋关节性脱位中的作用。方法:对在2002年6月～2011年11月我院门诊及住院18例先天性髋关节脱位患儿临床资料进行回顾性分析。通过手法检查和X线摄影检查,对先天性髋关节脱位的性质和位置进行确定性诊断。结果:18例患儿确诊15例,漏诊3例,诊断符合率83.3%。结论:X线摄影是明确先天性髋关节脱位诊断的重要依据,是临床早期发现早期诊疗先天性髋关节脱位的关键。     

充填法硬膜外阻滞对胎儿生长受限患者血浆一氧化氮的影响

目的观察充填法硬膜外阻滞对胎儿生长受限(FGR)患者血浆一氧化氮(NO)的影响。方法将60例FGR患者随机分为治疗组和对照组,每组30例。治疗组采用连续充填法硬膜外阻滞(0.3%罗哌卡因混合液)治疗,导管保留7d;对照组常规治疗7d。测量治疗前与治疗后第8天2组血清NO指标,同时记录患者的不良反应及胎儿脐血流指标。结果治疗组治疗后血清NO水平较治疗前明显上升(P<0.05);治疗后,2组脐血流指标均显著下降(P<0.05),治疗组的RI、S/D比值下降程度显著大于对照组(P<0.05),且不良反应轻微。结论充填法硬膜外阻滞可以有效提高FGR患者血浆NO水平,从而改善子宫胎盘血流量,促进胎儿生长发育。     

中西医结合治疗小儿咳嗽变异性哮喘疗效观察

目的:观察中西医结合治疗小儿咳嗽变异性哮喘的疗效.方法:230例咳嗽变异性哮喘患儿随机分为观察组和对照组各115例,对照组给予孟鲁司特钠治疗,观察组在对照组基础上采用射干麻黄汤加减治疗.观察两组咳嗽缓解和消失时间、复发情况、不良反应和临床疗效.结果:两组咳嗽缓解和消失时间、复发率、不良反应发生率和总有效率比较差异均有显著性(P＜0.05).结论:中西医结合治疗小儿咳嗽变异性哮喘疗效显著.