儿科背式输液架的研制与应用

输液架是医院不可缺少的工具之一，国内医疗单位使用的输液架多种多样，但仅适用于病房使用，而适合儿科患儿移动的背式输液架甚少。针对以上缺陷，我们自行设计了一种可调式背式移动输液架，已应用于500例儿科患儿，效果较好。现介绍如下。     

对1例疑难血交叉试验滴加白蛋白试剂的体会

<正> 多发性骨髓瘤(Multiple myeloma,MM)是浆细胞恶性增生所致的高粘滞综合征,其血清能使任何人包括自己的RBC形成缗钱状凝集,导致交叉配血困难。现就1例MM患者血交叉试验试用白蛋白试剂消除凝集,并与滴加生理盐水进行比较。 病例简介:男,59岁。经全身彩超、CT、心电图等系统检查确诊为MM。骨髓增生活跃,浆细胞占51％,其成熟RBC同外周血均成缗钱状凝集,血型A型,Hb52/L,WBC3.4×10~9/L,Pt94×10~9/L,ESR>150mm/h,IgG31.2g/L(正常8     

医患合作做胃镜

胃镜检查是诊断上消化道(包括食管、胃、十二指肠)疾病的重要方法之一。它在疾病的诊断方面有着其他仪器设备无法替代的作用。但检查过程中带来的痛苦,常使病友望而却步,形成“恐胃镜检查症”,结果拒绝检查,贻误了自己的病情。其实,在胃镜检查过程中,操作医生的技术熟练程度是一方面原因,另外,医患     

金双歧辅治婴幼儿湿疹40例报告

婴儿湿疹俗称“胎毒”、“奶癣”，是婴儿时期常见的变态反应性皮肤病。我院于2005年6月至2005年12月应用金双歧辅助治疗婴儿湿疹40例，现报告如下。[第一段]     

抽吸腹水的两种方法比较

自2003年10月至2005年10月我们应用非负压式一次性引流袋引流腹水68例。将该方法与常规50ml注射器反复抽吸腹水的方法进行比较，确实具有一定优越性。     

闽东农村婴幼儿腹泻病原学调查

对闽东农村５８２例婴幼儿腹泻患者进行细菌性病原调查，在２０８例腹泻患儿粪便中检出致泻菌２４６株，检出率为４２．２６％，其中ＥＴＥＣ７７株（１３．２３％），ＥＩＥＣ１９株（３．２６％），空肠弯曲菌１７株（２．９２％），沙门氏茵６株（１．０３％），亲水性气单胞菌２株（０．３４％）。表明致泻大肠杆菌（ＥＴＥＣ，ＥＰＥＣ，ＥＩＥＣ）是我区婴幼儿致泻主导菌群，占检出菌的６６．３％。混合感染率在农村腹泻患儿中高达１７．３％，值得临床工作者重视。     

甲状旁腺囊肿1例报告

甲状旁腺的微囊肿(microscopic cysts)常见,但囊肿大到足以产生临床症状者却罕见。偶遇1例,报道如下: 患者,男,37岁。一年多前左颈部出现蚕豆大小肿物,渐大。半年来渐感说活时喉部不适。诊为“左甲状腺瘤囊性变”入院。检查:颈部相当于甲状左下极部位有一鸭蛋大小之肿物,皮肤色泽正常,肿物无压痛,触之囊性感,随吞咽上下移动。入院后行左侧甲状腺次全切除术,术中见囊肿位于左甲状腺下极部位,一个大囊有6×4×3cm大小,旁有3～4个小泡状囊,正常甲状腺组织已被挤压成很小一片。囊与甲状腺组织交界部可见棕黄色“脂肪样”小团粒,疑为甲状旁腺,小心分离保留之,将大囊完整     

胃镜润滑胶浆用于胃镜检查232例

目的：探讨胃镜润滑胶浆在胃镜检查中对咽喉部麻醉及祛泡效果。方法：需作胃镜检查的患者446例，治疗组232例于检查前服用胃镜润滑胶浆10 mL，对照组214例直接进行胃镜检查，观察对咽喉部麻醉效果及祛泡效果。结果：治疗组与对照组的恶心反应轻微率分别为82.8%和53.3%；治疗组与对照组的镜下视野清晰率分别为77.6%和47.7%。治疗组均明显高于对照组(P＜0.01)。结论：采用胃镜润滑胶浆能起到快速表面麻醉和祛泡作用，操作简便，既减轻患者的痛苦，又便于镜下操作及诊断。     

塞来昔布对人鼻咽癌CNE-2细胞生长抑制及放射增敏研究

Objective To investigate the growth inhibition and radiosensitization of Celecoxib in hu-man nasopharyngeal carcinoma cell line CNE-2. Methods CNE-2 growth inhibition by Celecoxib was eval-uated by MTT method. Apoptosis-related changes in morphology were observed by transmission electron mi-croscopy (TEM). Cell cycle distribution and apoptosis rate were measured by flowcytometry (FCM). The ex-pression of COX-2 protein was observed by SP method after the treatment of Celecoxib. Cells were randomly planted into four groups: irradiation control(Ci), drug group(Cd), irradiation group(R), and Celecoxib plus irradiation group(D+R). Single irradiation of 2,4,6,8,and 10 Gy were administered for colonogenic assay. Cell cycle distribution and apoptosis rate were analyzed at 6 Gy irradiation. Results The growth of CNE-2 cell was inhibited by celecoxib in a dose-and time-dependent manner, the IC50 was 80 μmol/L After the treatment, cell ratio of GO and G, phases was increased (47.03±2.76 vs 56.17±1.95, t=4.68, P= 0.010), whereas the ratio of S and G2/M phases was decreased (33.07±1.86 vs 24.87±1.76, t=5.54, P = 0.010; 19.30±0.53: 17.73±0.83, t=2.75, P=0.050), and the apoptosis rate was increased (1.57±0.47:10.47±0.31, t = 27.39, P = 0.000) in a dose-dependent manner. Apoptosis with nuclear chromatin condensation, fragmentation and cell shrinkage was found by TEM. SP method showed that Celeib decreased COX-2 expression (17.48±0.34 vs 12.82±0.51,t=13.20,P =0.00). The sensitivity ratio(D0) was 1.15. FCM showed that the percentage of cells in G2/M phase was significanty more in R and D+R groups than in Ci and Cd groups (68.00±1.65,54.27±5.74,17.60±0.80,14.86±1.23, t=47.70,P=0.000; t=11.63, P=0.000), and also significantly different between R group and D + R group (t=3.99, P= 0.020). The apoptosis rate was higher in R and D + R groups than Ci and Cd groups(4.83±0.97,9.50± 1.35,1.33±0.86 and 2.28±0.42,t=4.67,P=0.010;t=8.81, P=0.000), D + R group than R group(t =4.85,P=0.010). Conclusions Celecoxib can markedly inhibit the growth and induce apoptosis in CNE-2 cells,which may depend on COX-2 pathway. Celeeoxib potently enhances the radiosensitivity of CNE-2 cells,which may due to the repair inhibit of radiation-induced DNA damage, inhibit of cell proliferation,and enhancement of cell apoptosis after irradiation.     

无痛胃镜对痛苦说“不”

无痛胃镜 胃镜检查被广泛应用于消化道系统疾病的筛查、鉴别、诊断、治疗及健康普查等方面。提供了更直观的画面和治疗新技术，极大地提高了消化道疾病诊断和治疗准确性。特别是在疾病的诊断方面有着其他仪器设备无法替代的作用。作为诊断工具，它可提供最准确的诊断信息；作为治疗工具，它具有损伤最轻、手术安全的特点。