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Estrogen improves the pathological changes of the local tissues and organs and recovers the tissue function by regulating the activity of tissue renin-angiotensin system (RAS) and the expression of RAS components in the local tissues such as heart, blood vessel, kidney, adrenal gland, brain and skeleton. Therefore, tissue RAS is the biological regulating targets of estrogen. Here we review the pathophysiological roles of estrogen in the local tissue RAS by analyzing and summarizing the recent researches. 相似文献
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