蛇床子炮制新法

蛇床子,为伞形科植物蛇床的果实,药理实验有激素样作用,我科常用其治疗男性不育症。然服用本品麻舌辣口,胃脘不舒,影响疗效.《本经》告戒:“未经法制者,慎弗轻投”.蛇床如何炮制,中药文献很少论述,我们经过反复实验,从盐、酒、醋姜、蜜、黄土水分别同蛇床共炒中筛选出后     

THE EFFECT OF TOOSENDANIN ON MONKEY BOTULISM

Rhesus monkeys were given one MLD of typeA botulismotoxin subcutaneously.Toosendanintherapy was initiated 24 hours after the challenge,with intravenous administration of the drug (0.9-1.0mg/kg)given to 13 monkeys,10 of which recoveredas compared with the survival of only 2 in the12 monkeys of the positive control group.Five of11 monkeys receiving intramuscular Toosendanin sur-vived and recovered;all 6 control monkeys died.Three of 6 monkeys given oral Toosendanin survived,while all 5 positive control monkeys died.The therapeutic effect of Toosendanin on monkeybotulism was evaluated with results showing thatToosendanin given via one of 3 different routes(iv,im and po) has definite therapeutic value in monkeyswith experimental botulism.     

[~3H]磷酸萘酚喹在小鼠体内的药物代谢动力学和放射自显影

［３Ｈ］磷酸萘酚喹在小鼠体内的药物代谢动力学和放射自显影王翠娥徐在海邹镜贾桂荣孟纪元袁本利１余寿忠１（军事医学科学院微生物学流行病学研究所，北京１０００７１，１毒物药物研究所，北京１００８５０）为了探讨磷酸萘酚喹致肝损伤的机理，我们用［３Ｈ］磷酸萘酚...