维思通治疗对精神分裂症患者社会功能恢复的影响

Background: Weisitong is a new type of antipsychotic,with balancing antagonistic function to dopamine D2 receptor and 5-HT2 receptor,is effective on both negative and positive symptoms of schizophrenia,has little side reaction of extrapyramidal tract,and has good tolerance. Objective: To evaluate the Weisitong's influence on social function's recovery of schizophreniac. Design: To estimate the curative effect with graphs of BPRS、SANS、SAPS before and after the intervention to 63 schizophreniacs.Unit: Mental Hygienics Center of Binzhou City. Subject: The 63 in-patients of schizophrenia who coincide with schizophrenia and its typing standard of China Mental Disease Classification Plan and Diagnose Standard(the 2nd revised edition)(CCMD-Ⅱ-R),among them,male 32 cases,female 31 cases,average age(29.17± 9.82),average course of disease(5.67± 6.5) years.49 cases have used other antipsychotics before this therapy,27 cases' family history is positive.     

维思通和氯丙嗪治疗慢性精神分裂症的对照研究

目的：研究维思通和氯丙嗪治疗慢性精神分裂症的疗效。方法：将符合入组条件的病人随机分为2组，分别服用维思通或氯丙嗪治疗12周，采用BPRS、TESS疗效评定标准进行评定。结果：2组总有效率的差异虽无显著性，但显效率维思维通组明显高于氯丙嗪组（X^3＝4．06，P＜0．05）。维思通组对BPRS量表的总分及因子分均优于氯丙嗪组。结论：维思通对慢性精神分裂症的疗效优于氯丙嗪。对患者恢复社会功能，降低残疾程度疗效肯定，效果明显，不失为一种有效的治疗方法。     

The Weisitong's influence on social function's recovery of schizophreniac

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60例酒依赖的临床治疗研究

目的：探讨酒依赖的治疗方法。方法：对60例酒依赖患者采用厌恶疗法合用改善脑功能药物与单用厌恶疗法治疗进行临床观察。疗程6周，采用戒断症状量表、汉密尔顿焦虑量表（HAMA）和有关实验室等检查评定疗效和副反应。结果：实验组（厌恶疗法合用改善脑功能药物）的疗效明显优于对照组（单用厌恶疗法）(x^2=4.329，P＜0.05），两组副反应均很少且轻微。结论：对酒依赖的治疗重在改善患者机体代谢功能，在此基础上戒酒可明显提高疗效。