肝素对炎症过程的影响

在临床上肝素广泛应用于防治血栓栓塞性疾病,弥漫性血管内凝血的早期治疗及体外抗凝。研究显示,肝素除具有抗凝作用外,还具有多种生物活性,其中,肝素对炎症过程的影响正日益受到关注。本文将从肝素与肥大细胞的关系、肝素抑制白细胞粘附于血管内皮及其随后向组织的迁移等方面来讨论肝素对炎症的影响及作用机制,并探讨肝素的抗炎作用应用于临床的前景。     

植物多糖在胃肠道及肝病中的新作用(英文)

Ｔｈｅｐｏｌｙｓａｃｃｈａｒｉｄｅｆｒａｃｔｉｏｎｆｒｏｍｖａｒｉｏｕｓｈｅｒｂａｌｍｅｄｉｃｉｎｅｓｈａｓｂｅｅｎｗｅｌｌｓｔｕｄｉｅｄｆｏｒｉｔｓｉｍｍｕｎｏｍｏｄｕｌａｔｏｒｙａｃｔｉｏｎａｎｄａｎｔｉｔｕｍｏｒｅｆｆｅｃｔ,ｓｕｃｈａｓｌｅｎｔｉｎａｎａｎｄｌｕｃｉｄＧａｎｏｄｅｒｍａ ,ｆｏｒｍｏｒｅｔｈａｎｔｗｅｎｔｙｙｅａｒｓ .Ｔｈｅｓｅａｃｔｉｏｎｓａｎｄｅｆｆｅｃｔｓｍａｙｂｅｄｕｅｔｏｓｔｉｍｕｌａｔｉｏｎｏｆｔｈｅｐｈａｇｏｃｙｔｉｃａｃｔｉｖｉｔｙａｎｄａｎｔｉ ｉｎｆｌａｍ…     

植物多糖在胃肠道及肝病中的新作用

The polysaccharide fraction from various herbal medicines has been well studied for its immunomodulatory action and antitumor effect, such as lentinan and lucid Ganoderma, for more than twenty years. These actions and effects may be due to stimulation of the phagocytic activity and anti-inflammatory action. It is also found to increase hematopoiesis in the bone marrow and to promote proliferation of several types of hematopoietic precursor cells. It was also found to provide radioprotective effect by improving the recovery of hematopoietic function in animals. These findings suggest that the polysaccharides from plant origins have significant pharmacological action on cells with high proliferative capacity in the body. Recently, increasing evidence implicates that vegetal polysaccharides have similar protective and repairing activities in the gastrointestinal (GI) tract as the cells in this system also have the same biological property. In this review, we would like to update and summarize findings both in animals and in human pertaining to the pharmacological actions of polysaccharides from different vegetal sources on the GI and hepatic disorders including ulcer and cancer diseases.