Retrospective Study on the Efficacy and Safety of Quinacrine Sterilization

Objective To observe and evaluate the efficacy and safety of quinacrine sterilization.Methods A total of 572 cases of quinacrine sterilization preformed during the 4 years from 1993to 1997in Jiangsu and Guizhou Provinces were employed in this study. The efficacy and safety of quinacrine sterilization in those case were studied and evaluated, with 588 cases of surgical sterilization performed at the same time being the control group.Results Both groups were with identical demographic and gynecological characteristics. The result of multiple decrement life table analysis showed the 12th gross cumulative failure rates for quinacrine sterilization was 3. 13% and serious side effects occurred in only 2 cases accounting for O. 35%. One was ectopic pregnancy (20 months after treatment). The other was due to anaphylaxis in 10 minutes after the second insertion). No difference in the liver and nephic functions was detected and no suspected cancer cells or cancer cells were found in the two groups. 99. 6% of the 572 women interviewed accepted the quinacrine sterilization.Conclusions Quinacrine sterilization method is with high acceptability but comparatively low effectiveness. It has been proved to be a safe method of contraception in short-term. However, the safety of long-term still needs further study.     

米索前列醇、利多卡因和仕泰栓在人流术中镇痛效果的临床分析

目的总结分析米索前列醇、利多卡因和仕泰栓3种药物用于人工流产手术中的临床镇痛效果。方法选择自愿终止妊娠的早孕妇女597例,术前随机分为3组:A组口服米索前列醇片;B组宫颈旁注射利多卡因;C组肛门塞仕泰栓。结果A、B、C3组的无痛率分别为91.9%,93.4%和89.2%;宫颈松弛率分别为90.7%、83.5%和85.8%;出血量>30ml者分别为4.7%、7.4%和5.1%;人流综合征发生率分别为2.3%、2.6%和2.8%。结论3种药物用于人工流产术中的镇痛效果明显,宫颈松弛情况良好,出血量较少,人流综合征发生率较低,受术者易于接受。     

米非司酮与米索前列醇用于催经的研究

目的　评估应用米非司酮联合米索前列醇催经的效果及副反应。　方法　在全国 8个研究中心共接收了 72 0名妇女 ,平均预期月经延迟 ( 4.9± 1 .7) d。接纳当天给予 1 50 mg米非司酮 ,3 6～ 48h后门诊阴道放置 40 0μg米索前列醇 ,并留院观察 1 h。嘱服药后 1 0 d内随诊。观察指标主要为妊娠、月经来潮。测定血清雌二醇 ( E2 )及孕酮 ( P) ,以分析月经延迟时的周期时相。　结果　在 72 0名妇女中失访 1人。在 71 9名妇女中 ,就诊时已经妊娠 492人 ,其中完全和不完全流产 46 7例 ( 95.0 % ) ;妊娠继续 2 4例 ( 4.9% ) ;异位妊娠 1例 ,作进一步处理。月经延迟 2 2 7名妇女 ,其中月经来潮 2 2 2例 ( 97.8% ) ;月经延迟>45d或停经者 5例 ( 2 .2 % )。服药后副反应中有恶心 9%、呕吐 3 .1 %。血清 E2 与 P显示 ,月经延迟者有 6 0 %仍处于卵泡期水平 ,仅 3 0 %处于黄体期 ;在妊娠组 ,6 0 %血清 P和E2 的水平相当于黄体期水平 ,说明已有极早期妊娠。　结论　米非司酮与米索前列醇联合应用是有效和安全的催经止孕方法 ,对解决妇女担忧非意愿妊娠有利 ,免除在以后寻求流产     

平均活产数影响因素的研究

本文应用多元分类分析和多元回归分析法研究了江苏省农村地区已婚妇女平均活产数的影响因素。结果表明,随着妇女结婚时间的推迟,平均活产数大幅度下降。三十年中,1951～1954年结婚妇女平均活产数为4.15,而1980～1984年结婚妇女仅1.32。影响平均活产数的因素依次为妇女结婚年代、丈夫工种、妇女出生年代、地区、经济水平、妇女工种及丈夫年龄。结果还表明,不同地区影响平均活产数的因素可有不同。     

围绝经期女性激素的测定与健康

正常月经是排卵的反映,绝经则表示妇女生殖功能的结束.绝经前卵巢已可能不排卵,卵巢性激素的分泌必然有较大的变化,伴随卵巢的功能衰竭,身体多种生理变化也开始发生,至绝经后1～2年间妇女可能出现各种症状和功能衰竭[1].WHO指出,围绝经期一定要包括绝经前一段时期及绝经后一年.本文就绝经前后这一时期所伴随的生殖激素变化和健康问题进行探讨.     

江苏省青少年生殖健康基本状况调查

目的:了解江苏省青少年生殖健康知识、态度、行为及服务的基本状况,为开展生殖健康教育与服务提供科学依据。方法:采用整群随机抽样方法,对7043名15～24岁青少年采用匿名自填式调查表进行问卷调查。结果:应答者平均年龄为19.85岁,性知识回答正确率为51.7%,性病及艾滋病知识回答正确率为56.51%。50.41%的人赞成婚前性行为。恋爱中有性交的占7.7%,其中采取避孕措施66.94%。希望计划生育部门提供服务的依次为性知识教育、生殖健康咨询、性病和艾滋病的预防知识(70.54%、66.24%、51.3%)。结论:应加强对江苏省青少年生殖健康教育与服务。     

A Comparison of 28 Months Performance of 4 Different IUDs in Breastfeeding Women Peasants

This is an experimental epidemiologic study comparing the performance of Stainless Steel Ring ( SSR) , Uterine Cavity-Shaped Device ( UCD ) , MLCu250 and TCu220c in breastfeeding women peasants, 711 healthy women, para 1 and gravida 1,22-32years of age, 3-9 months post-partum were randomly allocated to 4 groups receiving 4 different devices single-blindedly. They were followed up regularly. The results showed that 28 months after insertion, the use-ralated termination rates of UCD appeared to be the lowest,followed by MLCu250, TCu220c, and SSR in an increasing order. There were very significant differences among the use-related termination rates of four IUDs. SSR had higer termination rates than those of MLCu250 and TCu220c. The removals due to bleeding and pain were much higher in TCu220c than in MLCu250.     

B超在米非司酮和PG终止早孕中的监护

Ｂ超在米非司酮和ＰＧ终止早孕中的监护吴周亚，袁新华，丁婉华，申素琪米非司酮是一种甾体抗争激素制剂，与前列腺素（ＰＧ）联用已被证实是一种安全、有效的非手术终止早孕的方法［１～６］。随着国产米非司酮的问世，目前药物流产已为越来越多的妇女所接受。为了提高药...     

MLCu375和不锈钢单环节育器效果对比研究

为优选适合我国妇女应用的宫内节育器,本研究对Multiload Cu375(以下简称MLCu375)及不锈钢单环(以下简称单环)作了临床效果与反应的对比观察,报道如下。已育健康妇女324人,年龄24～39岁,产次1～2;其中30岁以下占56％,一产占94％,于经后3～7天按随机分配法由专人放置节育器。计MLCu375 161例,单环163例。两组妇女年龄孕次、产次、既往避孕史的分布均相似。     

口服避孕药与妇女高血脂和高血压的关系

对连续服用国产１号避孕片（ＯＣ）５￣２５年的健康农村妇女９９９名及同期使用宫内节育器（ＩＵＤ）妇女１０６５名的脂代谢和血压均值进行对比，对高血压和高血压患病率及危险性进行分析。结果：长期服用ＯＣ妇女ＴＧ、ＴＣ、ＨＤＬ水平和高甘油三脂症的患病率高于ＩＵＤ组（Ｐ〈０．０１），而高胆固醇症与对照组差异无显著性。ＯＣ组的收缩压和舒张压均值分别比ＩＵＤ组高６．５７和３．２４ｍｍＨｇ（１ｍｍＨｇ＝０．１３３３