全文获取类型
收费全文 | 730篇 |
免费 | 63篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 21篇 |
妇产科学 | 5篇 |
基础医学 | 47篇 |
口腔科学 | 45篇 |
临床医学 | 42篇 |
内科学 | 97篇 |
皮肤病学 | 16篇 |
神经病学 | 10篇 |
特种医学 | 101篇 |
外科学 | 58篇 |
综合类 | 29篇 |
预防医学 | 37篇 |
眼科学 | 241篇 |
药学 | 33篇 |
中国医学 | 1篇 |
肿瘤学 | 24篇 |
出版年
2023年 | 4篇 |
2020年 | 6篇 |
2018年 | 17篇 |
2017年 | 8篇 |
2016年 | 15篇 |
2015年 | 10篇 |
2014年 | 7篇 |
2013年 | 25篇 |
2012年 | 25篇 |
2011年 | 27篇 |
2010年 | 22篇 |
2009年 | 31篇 |
2008年 | 27篇 |
2007年 | 51篇 |
2006年 | 20篇 |
2005年 | 19篇 |
2004年 | 20篇 |
2003年 | 13篇 |
2002年 | 19篇 |
2001年 | 12篇 |
2000年 | 15篇 |
1999年 | 10篇 |
1998年 | 21篇 |
1997年 | 39篇 |
1996年 | 34篇 |
1995年 | 20篇 |
1994年 | 18篇 |
1993年 | 18篇 |
1992年 | 14篇 |
1991年 | 17篇 |
1990年 | 16篇 |
1989年 | 29篇 |
1988年 | 29篇 |
1987年 | 20篇 |
1986年 | 19篇 |
1985年 | 20篇 |
1984年 | 14篇 |
1983年 | 14篇 |
1982年 | 8篇 |
1981年 | 11篇 |
1980年 | 9篇 |
1979年 | 4篇 |
1978年 | 8篇 |
1977年 | 4篇 |
1976年 | 6篇 |
1975年 | 3篇 |
1973年 | 2篇 |
1969年 | 3篇 |
1968年 | 1篇 |
1967年 | 1篇 |
排序方式: 共有810条查询结果,搜索用时 31 毫秒
1.
2.
While health promotion practitioners are engaging increasingly in research,
there has been little examination of the practical dilemmas they may face
in negotiating and collaborating with academics and community members in
action research projects. This paper analyses how the practice of health
promotion can interact with action research, and considers issues that
arise for organizationally based health promotion practitioners and
professional researchers. The first section charts types of action research
along three dimensions (power, goals/values, resources). The second section
examines some of the issues and practical dilemmas which arise in
negotiating and researching collaborative projects in community health
promotion. The discussion includes the differing perspectives of:
practitioners (managerial and frontline), community members and academic
researchers. The final section outlines a hybrid model of action research,
developed in our work with community members, organizationally based health
promoters and academy-based researchers. It combines the reflective
practice of practice-based action research with the community participation
and control of participatory research. The model is called community
reflective action research. 相似文献
3.
A morphometric study of endothelial cells of human corneas stored in MK media and warmed at 37 degrees C. 总被引:1,自引:1,他引:0
下载免费PDF全文
![点击此处可从《The British journal of ophthalmology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
No study has yet been done to investigate the changes in endothelial cell size, perimeter, and density that may result from the warming of corneas in MK (McCarey-Kaufman) medium for specular microscopy. In the present investigation eye bank eyes were stored in MK medium at 4 degrees C and rewarmed daily for six days at 37 degrees C before specular photography of the endothelium was performed. These photographs were compared with wet mount preparations stained with trypan blue and alizarin red made from the same corneas and those stored without rewarming for six days. In addition all corneas were qualitatively analysed with the scanning electron microscope (SEM). The data from serial specular photography were insufficient to allow significant conclusions to be drawn about day to day changes in cell morphology. However, analysis of wet mount preparations revealed that cell density and perimeter varied significantly between those corneas rewarmed daily and those held in cold storage for six days. SEM studies showed an intact cell monolayer with cell loss along the folds of corneal endothelium. We therefore concluded that repeated rewarming at 37 degrees C of corneas stored in MK medium at 4 degrees has a deleterious effect on cell morphology and that folds induced by swelling of corneal tissue result in endothelial cell damage with some loss. 相似文献
4.
Miriam Stewart Linda Reutter Edward Makwarimba Irving Rootman Deanna Williamson Kim Raine Doug Wilson Janet Fast Rhonda Love Sharon McFall Deana Shorten Nicole Letourneau Karen Hayward Jeff Masuda William Rutakumwa 《Revue canadienne de recherche en sciences infirmières》2005,37(3):104-131
Poverty influences health status, life expectancy, health behaviours, and use of health services. This study examined factors influencing the use of health-related services by people living in poverty. In the first phase, 199 impoverished users of health-related services in 2 large Canadian cities were interviewed by their peers. In the second phase, group interviews with people living in poverty (n = 52) were conducted. Data were analyzed using thematic content analysis. Diverse health-related services were used to meet basic and health needs, to maintain human contact, and to cope with life's challenges. Use of services depended on proximity, affordability, convenience, information, and providers' attitudes and behaviours. Use was impeded by inequities based on income status. To promote the health of people living in poverty, nurses and other health professionals can enhance the accessibility and quality of services, improve their interactions with people living in poverty, provide information about available programs, offer coordinated community-based services, collaborate with other sectors, and advocate for more equitable services and policies. 相似文献
5.
The role of growth factors and cytokines in the impaired healing of chronic leg ulcers remains uncertain. The aim of this study was to determine whether changes in the amount and location of cytokines and growth factors may be associated with impaired healing in chronic leg ulcers. Biopsies from leg ulcers of 21 patients and from normal skin of nine healthy volunteers were examined immunohistochemically for selected growth factors and cytokines. Greater staining intensity was found in keratinocytes at the edges of ulcers compared to normal skin, or skin adjacent to the ulcers. Staining at the ulcer edge was more intense in nonhealing ulcers for only vascular endothelial growth factor and platelet-derived growth factor, whereas staining in the adjacent skin was more intense for all factors in the nonhealing phase. For all factors staining was cytoplasmic, suggesting production in these areas. This study shows up-regulation of the production of cytokines and growth factors in keratinocytes of chronic leg ulcers that is greater when the ulcers are nonhealing. 相似文献
6.
7.
8.
9.
10.
Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease. 总被引:1,自引:0,他引:1
Collins CE Benson MJ Burnham WR Rampton DS 《Alimentary pharmacology & therapeutics》1996,10(3):315-320
BACKGROUND: Inflammatory bowel disease is associated with increased mucosal release of eicosanoids. Among these, thromboxane A2 has been proposed as a possible inflammatory mediator; its suppression may be a useful therapeutic option. METHODS: Using a tissue incubation technique, we compared release of immunoreactive thromboxane B2 by colonic biopsies from patients with ulcerative colitis, Crohn's disease and controls, and assessed the inhibitory effect of picotamide, a thromboxane synthesis inhibitor-receptor antagonist, which has been widely used in Italy for management of ischaemic heart and cerebrovascular disease. RESULTS: Increased amounts of thromboxane B2 were released from biopsies from patients with active ulcerative colitis (median 238 pg/20 min/mg wet weight (interquartile range 147- 325), n = 12) and active Crohn's disease (252 (174-450), 6) compared with those from patients with quiescent ulcerative colitis (95 (61- 140), 12) or Crohn's disease (105 (57-201), 13), or controls (136 (64- 206), 8). Incubation with picotamide at concentrations between 100 microM and 1 mM reduced thromboxane B2 release (IC50 890 microM). CONCLUSION: Since increased thromboxane A2 production may have pathogenetic importance, thromboxane synthesis inhibitor-receptor antagonists such as picotamide merit therapeutic trial in the management of inflammatory bowel disease. 相似文献