全文获取类型
收费全文 | 678篇 |
免费 | 39篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 56篇 |
妇产科学 | 13篇 |
基础医学 | 69篇 |
口腔科学 | 5篇 |
临床医学 | 47篇 |
内科学 | 235篇 |
皮肤病学 | 6篇 |
神经病学 | 19篇 |
特种医学 | 56篇 |
外科学 | 48篇 |
综合类 | 14篇 |
预防医学 | 39篇 |
眼科学 | 27篇 |
药学 | 58篇 |
中国医学 | 3篇 |
肿瘤学 | 19篇 |
出版年
2024年 | 5篇 |
2023年 | 16篇 |
2022年 | 23篇 |
2021年 | 49篇 |
2020年 | 23篇 |
2019年 | 28篇 |
2018年 | 31篇 |
2017年 | 23篇 |
2016年 | 17篇 |
2015年 | 16篇 |
2014年 | 28篇 |
2013年 | 43篇 |
2012年 | 36篇 |
2011年 | 47篇 |
2010年 | 38篇 |
2009年 | 10篇 |
2008年 | 33篇 |
2007年 | 31篇 |
2006年 | 16篇 |
2005年 | 25篇 |
2004年 | 19篇 |
2003年 | 32篇 |
2002年 | 28篇 |
2001年 | 11篇 |
2000年 | 6篇 |
1999年 | 7篇 |
1998年 | 10篇 |
1997年 | 4篇 |
1996年 | 6篇 |
1995年 | 2篇 |
1994年 | 2篇 |
1993年 | 8篇 |
1991年 | 5篇 |
1990年 | 6篇 |
1989年 | 4篇 |
1988年 | 4篇 |
1987年 | 4篇 |
1984年 | 1篇 |
1980年 | 1篇 |
1977年 | 1篇 |
1975年 | 3篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1971年 | 1篇 |
1970年 | 2篇 |
1969年 | 1篇 |
1967年 | 2篇 |
1966年 | 2篇 |
1961年 | 1篇 |
1960年 | 2篇 |
排序方式: 共有717条查询结果,搜索用时 15 毫秒
1.
2.
Randomised controlled trial of near-patient testing for glycated haemoglobin in people with type 2 diabetes mellitus
下载免费PDF全文
![点击此处可从《The British journal of general practice》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Kamlesh Khunti Margaret A Stone Andrew C Burden David Turner Neil T Raymond Mary Burden Richard Baker 《The British journal of general practice》2006,56(528):511-517
BACKGROUND: Tight glycaemic control in people with type 2 diabetes can lead to a reduction in microvascular and possibly macrovascular complications. The use of near-patient (rapid) testing offers a potential method to improve glycaemic control. AIM: To assess the effect and costs of rapid testing for glycated haemoglobin (HbA1c) in people with type 2 diabetes. DESIGN OF STUDY: Pragmatic open randomised controlled trial. SETTING: Eight practices in Leicestershire, UK. METHOD: Patients were randomised to receive instant results for HbA1c or to routine care. The principal outcome measure was the proportion of patients with an HbA1c <7% at 12 months. We also assessed costs for the two groups. RESULTS: Of the 681 patients recruited to the study 638 (94%) were included in the analysis. The mean age at baseline was 65.7 years (SD = 10.8 years) with a median (interquartile range) duration of diabetes of 4(1-8) years. The proportion of patients with HbA1c < 7% did not differ significantly between the intervention and control groups (37 versus 38%, odds ratio 0.95 [95% confidence interval = 0.69 to 1.31]) at 12 months follow up. The total cost for diabetes-related care was 390 UK pounds per patient for the control group and 370 UK pounds for the intervention group. This difference was not statistically significant. CONCLUSION: Near-patient testing for HbA1c alone does not lead to outcome or cost benefits in managing people with type 2 diabetes in primary care. Further research is required into the use of rapid testing as part of an optimised patient management model including arrangements for patient review and testing. 相似文献
3.
4.
5.
Rehan Asif Kamlesh Chandra Vanita Chopra M. L. B. Bhatt 《Indian journal of otolaryngology and head and neck surgery》2003,55(2):94-96
Management of Head and Neck Cancers poses a challenge inspite of several advances because of poor success in terms of response
rate, survival and reduced morbidity of the patients. In the present study 30 untreated histologically proven cases of head
and neck cancers were subjected to weekly radiotherapy with adjuvant chemotherapy (cisplatin 30 mg/m2 intravenously). This study group was compared with a group of 30 patients who were given only radiotherapy. Results have
shown that combination of chemotherapy with radiotherapy gives a significantly better results in tumour as well as nodal response
with minimal toxicities. 相似文献
6.
Dudani R Giordano L Sultania P Jha K Florens A Joseph T 《American journal of perinatology》2008,25(4):229-231
Juvenile granulosa cell tumor (JGCT) of testis is extremely rare in childhood. It is considered a benign entity because metastasis has never been reported. Testicular-sparing surgery is the recommended treatment. We reported this case in a newborn who presented with unilateral scrotal swelling. Histopathology and immunohistochemistry confirmed JGCT. Follow-up at 6 months after surgery did not show any recurrence. Even though JGCT is very rare in childhood, it is one of the important differentials of newborn scrotal mass. 相似文献
7.
8.
Franciskos Arsenyadis Ehtasham Ahmad Emma Redman Thomas Yates Melanie Davies Kamlesh Khunti 《Nutrients》2022,14(9)
Background: Omega-3 polyunsaturated fatty acids′ concurrent benefits for cardiometabolic and mental health are equivocal. Despite lack of evidence, up to a third of adults consume Omega-3 supplements. No review has yet been published to report effect on depression in this cardiometabolic population. Methods: We conducted a systematic review of double-blinded, controlled randomised trials to investigate the safety and effect of Omega-3 supplementation on depression scores in people with cardiometabolic diseases. Primary outcome was change in depression scores versus placebo. Secondary outcomes were side-effects, concurrent medication and adherence. Results: Seven trials reporting on 2575 (672 female) adults aged 39–73 were included. Omega-3 dosages ranged from 1–3 g with an intervention duration of 10–48 weeks. Six out of seven trials found no statistically or clinically significant change to depression scores compared to placebo. One trial favoured intervention (Relative Risk Reduction: 47.93%, 95% CI: 24.89–63.98%, p < 0.001). Sub-analyses showed clinically meaningful reductions in depression scores for those on antidepressants (Intervention: 20.9 (SD: 7.1), Placebo: 24.9 (SD: 8.5) p < 0.05) or with severe depression (−1.74; 95% CI −3.04 to −0.05, p < 0.05) in two separate trials. Side effects were comparable between treatment arms. Conclusions: Omega-3 supplementation is safe to use but not superior to placebo for depression in adults with concurrent cardiometabolic disease. 相似文献
9.
Melioidosis is endemic in the South Asian regions, like Thailand, Singapore Malaysia and Australia. The disease is more pronounced in the southern part of the country. It is caused by Burkholderia pseudomallei which causes systemic involvement, morbidity and mortality associated with the disease is high. Due to highly varied clinical presentation, and low general awareness this infection is largely underdiagnosed and under reported in our country. Most laboratories in the country still rely on conventional culturing methods with their low sensitivity, adding to the under reporting. To enhance physician awareness we describe here two cases who presented to our institute after months of misdiagnosis. 相似文献
10.