全文获取类型
收费全文 | 420篇 |
免费 | 23篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 55篇 |
妇产科学 | 14篇 |
基础医学 | 31篇 |
口腔科学 | 12篇 |
临床医学 | 56篇 |
内科学 | 110篇 |
皮肤病学 | 13篇 |
神经病学 | 19篇 |
特种医学 | 42篇 |
外科学 | 49篇 |
综合类 | 7篇 |
预防医学 | 13篇 |
眼科学 | 1篇 |
药学 | 15篇 |
肿瘤学 | 10篇 |
出版年
2023年 | 4篇 |
2022年 | 3篇 |
2021年 | 5篇 |
2020年 | 6篇 |
2019年 | 8篇 |
2018年 | 8篇 |
2017年 | 8篇 |
2016年 | 14篇 |
2015年 | 25篇 |
2014年 | 34篇 |
2013年 | 40篇 |
2012年 | 54篇 |
2011年 | 25篇 |
2010年 | 17篇 |
2009年 | 14篇 |
2008年 | 21篇 |
2007年 | 14篇 |
2006年 | 9篇 |
2005年 | 10篇 |
2004年 | 8篇 |
2003年 | 6篇 |
2002年 | 6篇 |
2001年 | 7篇 |
2000年 | 2篇 |
1999年 | 3篇 |
1998年 | 12篇 |
1997年 | 9篇 |
1996年 | 16篇 |
1995年 | 8篇 |
1994年 | 7篇 |
1993年 | 7篇 |
1992年 | 2篇 |
1990年 | 2篇 |
1989年 | 3篇 |
1988年 | 5篇 |
1987年 | 3篇 |
1986年 | 1篇 |
1985年 | 3篇 |
1984年 | 3篇 |
1983年 | 6篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 3篇 |
1976年 | 1篇 |
1975年 | 1篇 |
排序方式: 共有449条查询结果,搜索用时 156 毫秒
1.
FE Preston 《Journal of clinical pathology》1987,40(12):1489-1490
2.
Influence of chronic morphine exposure on serum LH, FSH, testosterone levels, and body and testicular weights in the developing male rat 总被引:6,自引:0,他引:6
Yilmaz B Konar V Kutlu S Sandal S Canpolat S Gezen MR Kelestimur H 《Archives of andrology》1999,43(3):189-196
Opiate abuse has been a matter of serious concern in male adolescents. This study investigates the effects of chronic morphine administration on serum luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone levels, testicular histology, and body and testes weight in developing male rats. Animals were subcutaneously injected with morphine (5 mg/kg) or saline (1 mL/kg) twice daily for 30 days. Body weight determinations and injections were carried out under light ether anesthesia. At the end of the experiments, the rats were decapitated and blood samples were collected. Serum levels of LH and FSH were measured. Chronic morphine administration significantly decreased decreased serum testosterone (p < .02) and LH (p < .01) levels, but not FSH release compared to controls. Morphine exposure reduced body weight (p < .01), but had no significant effect on the testicular weight. When the testicular tissue was histologically examined, structural features of the seminiferous tubules and Leydig cells were similar in both saline and morphine-treated animals. The results suggest that opiates affect testosterone release through the hypothalamo-hypophyseal-gonadal axis rather than by a local testicular mechanism. Chronic morphine exposure during sexual maturation may have long-term endocrine disturbances in male rats. 相似文献
3.
4.
5.
6.
Home therapy with porcine factor VIIIC was safe and effective when administered to five hemophilic patients over periods of 8 1/2, 6, 4, 3 1/2, and 2 years. No significant transfusion reactions occurred. Before treatment with porcine factor VIIIC, all five had high-level, high- responding anti-human VIIIC inhibitors initially lacking anti-porcine factor VIIIC activity. Although specific anti-porcine VIIIC inhibitors arose in all patients, these were generally transient, and only one patient became refractory to treatment. We believe that porcine factor VIIIC is the treatment of choice in patients whose inhibitors do not cross-react. All five patients lost their original anti-human VIIIC inhibitors after starting treatment with porcine VIIIC, permitting the reintroduction of human VIIIC in three of them. There has been no recurrence of anti-human VIIIC inhibitor activity during 2 to 3 years of regular treatment with human VIIIC in these patients. This suggests that tolerance to human VIIIC has arisen as a result of treatment with porcine VIIIC. Porcine VIIIC may have a role in the desensitization of some factor VIIIC inhibitor patients. 相似文献
7.
Sadrettin Ekmen Nurdan Uras Mehmet Yekta Oncel Fatma Nur Sari Fuat Emre Canpolat 《The journal of maternal-fetal & neonatal medicine》2015,28(8):924-927
Objective: To evaluate the effect of dopamine on thyroid hormone tests and prolactin (PRL) and to assess requirement for L-thyroxin (LT4).Methods: The infants (n?=?102) were divided into three groups (Group 1; received no dopamine, Group 2 received ≤25?mg/kg cumulative dose and Group 3; received >25?mg/kg cumulative dose). Blood samples were taken at 6–8 days (timepoint 1), 13–15 days (timepoint 2), and 4–6 weeks of life (timepoint 3).Results: Respiratory distress syndrome was higher in group 2 and 3. Patnet ductus arteriosus was higher in group 3 than in groups 1 and 2. Duration and cumulative dose in group 3 were higher than group 2. There was no difference between thyroid hormones that were taken after stopping infusion at timepoint 3 among all groups. No therapy with LT4 was needed. PRL levels were higher at timepoint 1 in group 1 than compared to group 2 and 3 (p?0.05), and no difference between group 2 and 3 (p?>?0.05). This difference was disappeared at following timepoints.Conclusions: The release of TSH, FT3, FT4 and PRL were not inhibited and prophylactic thyroid hormone treatment was not required in VLBW infants receiving dopamine infusions. 相似文献
8.
9.
10.