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Rodricks Daniel Loya Asad Mohamed Mohamed Al-Mohtaseb Zaina 《International ophthalmology》2022,42(7):2039-2046
International Ophthalmology - Open globe injury (OGI) is a serious form of ocular trauma that can significantly lower quality of life post-injury due to comorbidities. This study was designed to... 相似文献
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Andres S. Parra Bryan M. Roth Taylor M. Nguyen Li Wang Stephen C. Pflugfelder Zaina Al-Mohtaseb 《The ocular surface》2018,16(2):254-258
Purpose
To describe changes in visual acuity in patients fit with the Prosthetic Replacement of Ocular Surface Ecosystem (PROSE) with irregular corneas compared to those with ocular surface disease, as well as describe patient demographics and fitting indications for PROSE at an academic medical center.Methods
A retrospective chart review from 2010 to 2016 on a total of 825 eyes from 493 patients fitted with a PROSE lens, and grouped by etiology, either irregular cornea/dystrophy or ocular surface disease and associated sub-etiologies. We compared best corrected visual acuity (BCVA) before and after PROSE fitting.Results
The irregular cornea group (n?=?262 eyes) included corneal scar (n?=?57), dystrophy (n?=?17), post-operative corneal irregularity (n?=?70), and primary ectasia (n?=?118). The OSD group included 563 eyes. For all etiologies combined, mean BCVA prior to PROSE fitting compared to after improved by 0.28 logMAR (p?<?.001). In the irregular cornea group, the mean BCVA improved by 0.46 logMAR (p?<?.001), while the improvement in BCVA for the OSD group was 0.20 logMAR (p?<?.001). All etiologies in the irregular cornea group demonstrated improvement in BCVA (p?<?.05) with the exception of post-PRK (n?=?2). BCVA improvement was found for all sub-etiologies in the OSD subgroup (p?<?.05).Conclusions
PROSE treatment had a positive impact on visual acuity for a wide range of corneal irregularities and ocular surface disease, suggesting that PROSE lenses may offer improvements in visual acuity without risks inherent to surgery. 相似文献4.
Cameron Clarke Eric Smith Mahmood Khan Zaina Al-Mohtaseb 《Journal of medical systems》2018,42(12):258
Recent research has analyzed how patients use social media, but little information exists evaluating how patients utilize social media in the perioperative period or how ophthalmologists and eye institutions integrate social media into their practices. This observational study aimed to examine (1) how patients interact on social media when undergoing LASIK and (2) how ophthalmologists and (3) eye institutions utilize social media accounts. We analyzed 2592 Instagram posts between August 2016 and April 2017 on a related hashtag (#lasiksurgery). Content was coded based on time frame of the post in relation to the procedure, references to return to work/activity, post-surgical photographs, mention of the surgical institution, tone, and complaints regarding the procedure. Twitter and Instagram accounts for 30 ophthalmologists and eye institutes were also located. The 20 most recent posts were categorized by message type and topic (physicians, patients, education, conference, etc.). Patients using the hashtag posted photographs (92%), had a positive tone (88%), referenced the clinic where they were treated (62%), and posted during the day of the procedure (44%). Ophthalmologists’ personal tweets focused on research conferences (35%), personal topics (25%), and the accomplishments of other physicians (21%). Eye institutions generally posted content relating to institutional promotion (22%), physician accomplishments (20%), and research publications (19%). Similar to other medical specialties, ophthalmology has a meaningful presence on both Twitter and Instagram. While LASIK patients tend to comment on their renewed vision and return to activity, ophthalmologists post to promote their research and accomplishments. 相似文献
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de Souza Rodrigo Guimaraes Golla Abhinav Khan Mahmood de Oca Ildamaris Montes Khandelwal Sumitra Al-Mohtaseb Zaina 《International ophthalmology》2022,42(1):27-33
International Ophthalmology - The purpose of this study is to determine the correlation between subjective and optical measurements used during cataract evaluation, including the iTrace... 相似文献
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Sakai Y Shaw CA Dawson BC Dugas DV Al-Mohtaseb Z Hill DE Zoghbi HY 《Science translational medicine》2011,3(86):86ra49
To uncover shared pathogenic mechanisms among the highly heterogeneous autism spectrum disorders (ASDs), we developed a protein interaction network that identified hundreds of new interactions among proteins encoded by ASD-associated genes. We discovered unexpectedly high connectivity between SHANK and TSC1, previously implicated in syndromic autism, suggesting that common molecular pathways underlie autistic phenotypes in distinct syndromes. ASD patients were more likely to harbor copy number variations that encompass network genes than were control subjects. We also identified, in patients with idiopathic ASD, three de novo lesions (deletions in 16q23.3 and 15q22 and one duplication in Xq28) that involve three network genes (NECAB2, PKM2, and FLNA). The protein interaction network thus provides a framework for identifying causes of idiopathic autism and for understanding molecular pathways that underpin both syndromic and idiopathic ASDs. 相似文献
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Zaina N. Al-Mohtaseb Li Wang Mitchell P. Weikert 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2013,251(7):1855-1860
Background
To assess the repeatability and comparability of central corneal thickness (CCT) measurements obtained from the Galilei Dual Scheimpflug Analyzer (Galilei-DSA) and from ultrasonic pachymetry (USP) in normal eyes and in eyes following laser refractive surgery.Methods
In this prospective observational study, 77 eyes of 39 patients with normal corneas and 39 eyes of 20 patients with prior laser refractive surgery were enrolled. All 116 eyes had three repeated measurements of central CCT with the Galilei-DSA first and then with USP by the same examiner. Reliability of both devices was assessed statistically, and CCT measurements by each were compared.Results
The mean CCT measurement of normal eyes was 549.2 ± 30.5 μm and 548.5 ± 33.1 μm by the Galilei-DSA and USP respectively; the difference between the two modalities was ?0.7 ± 7.1 μm (P?=?0.365). In post-refractive surgery eyes, the mean CCT measured by the Galilei-DSA and USP was 500.4 ± 44.8 and 494.3 ± 50.3 respectively; the difference between the two devices was ?6.2 ± 9.9 μm (P?<?0.001). For the three repeated measurements, the mean standard deviation was 2 μm with the Galilei-DSA and 1.8 μm with USP in normal eyes, and 2.4 μm with the Galilei-DSA and 1.9 μm with USP in post-refractive surgery eyes.Conclusion
The Galilei-DSA has high repeatability and excellent to moderate agreement with ultrasonic pachymetry when measuring CCT in normal and post-refractive surgery eyes. 相似文献8.
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