糖尿病肾病患者合并视网膜病变发生率的分析

目的　观察糖尿病肾病 (DN)患者合并糖尿病视网膜病变 (DR)的发生率 .方法　确诊糖尿病肾病患者 75例 ,未并发肾病的 2型糖尿病患者 79例 ,详细检查眼底 ,可疑患者行眼底荧光血管造影确诊 .结果　DN组和NDN组DR的发生率均随病程增高 ,病程 <15年 ,DN组DR的发生率较NDN组DR的发生率明显增高 .结论　对糖尿病肾病者更需高度重视DR的发生     

角膜缘干细胞移植联合丝裂霉素C治疗复发性翼状胬肉

目的 观察自体角膜缘干细胞移植联合丝裂霉素C治疗复发件翼状胬肉的疗效.方法 将58例(62眼)复发性翼状胬肉患者随机分为2组,治疗组(32例,35跟)采用角膜缘于细胞移植联合应用丝裂霉素C;对照组(26例,27眼)单纯采用角膜缘干细胞移植术治疗.术后随访6～30个月并比较疗效.结果 治疗组1眼冉复发,再复发率2.86%;对照组5眼再复发,再复发率18.52%,两组差异具有统计学意义(P<0.05).治疗组角膜创面上皮平均愈合时间为(8.34 ±2.38)d,对照组为(7.21±2.55)d,差异无统计学意义(P>0.05).两组均未发现严重并发症.结论 角膜缘干细胞移植联合应用丝裂霉素C治疗复发性翼状胬肉再复发率低,并发症少,为复发性翼状胬肉安全和有效的治疗方法 .     

糖尿病肾病患者合并视网膜病变发生率的分析

目的观察糖尿病肾病(DN)患者合并糖尿病视网膜病变(DR)的发生率.方法确诊糖尿病肾病患者75例,未并发肾病的2型糖尿病患者79例,详细检查眼底,可疑患者行眼底荧光血管造影确诊.结果 DN组和NDN组DR的发生率均随病程增高,病程<15年,DN组DR的发生率较NDN组DR的发生率明显增高.结论对糖尿病肾病者更需高度重视DR的发生.     

VISX Star S3准分子激光原位角膜磨镶术治疗中高度散光

目的 观察VISXStarS3准分子激光原位角膜磨镶术治疗中高度散光的有效性、可预测性及安全性.方法 采用回顾性的研究方法对25例36只眼首次接受VISXStarS3准分子激光原位角膜磨镶术的患者进行分析,入选患者散光均在2.0D以上且无角膜瓣并发症,术后随访至少6个月以上,观察术后裸眼视力、最佳眼镜矫正视力、残余散光度、散光的向量改变以及术后眩光发生情况.结果 术前柱镜度平均(-2.65±0.70)D(-2.0～-4.25D),平均球镜度(-6.28±3.05)D,范围+0.5～-13.25D;术后83.3%视力在1.0以上,97.2%视力在0.5以上;16.7%最好矫正视力下降1行,没有出现最佳矫正视力下降超过1行的情况.术后平均残余散光度(0.46±0.44)D(0～1.25D),58.3%残余散光在±0.5D以内,94.4%残余散光在±1.0D以内,平均矫正指数为(0.98±0.18),平均失误角(3.30±3.8)度.25例中,6例患者术后至少有1只眼出现持续的夜间视力障碍或眩光.结论 VISXStarS3准分子激光原位角膜磨镶术治疗中高度散光有良好的有效性、可预测性及安全性,但仍有相当比例的患者发生夜间眩光.     

LASIK治疗高度近视术后泪液学检查改变发生率的分析

目的:观察高度近视患者在行准分子激光原位角膜磨镶术(LASIK)后不同时间泪膜及泪液分泌功能减弱的发生率.方法: 对本院眼科行准分子激光治疗的82例(164眼)轻中度近视患者,54例(108眼)高度近视患者在行LASIK术后1周、1、3、6月作BUT及SchirmerⅠ泪液分泌检查.结果: 高度近视患者在行LASIK术后6个月内泪膜稳定性下降的发生率及术后3个月内泪液分泌功能减弱的发生率均较轻中度近视患者显著增高(P＜0.05),但两组的发生率均随时间的推移而减少.结论: 高度近视患者在LASIK术后泪膜稳定性及泪液分泌功能降低持续时间较长,但最终可随着时间的推移而缓解.     

幼儿睫毛及睑缘阴虱寄生1例

（耻）阴虱为性传播疾病，发病多见于具性行为能力的青壮年。獐特别是婴幼儿病人罕见。今发现1例，报道如下：     

图形视诱发电位,定量静态视野在老年性黄斑变性早期诊断中应用

目的观察老年性黄斑变性(AMD)视力,视野,视诱发电位(P-VEP)之间的关系,选择黄斑部病变电生理学诊断最佳刺激参数.方法早期AMD患者52眼,正常对照组80眼分别检测P-VEP,中央10°范围视网膜光敏度(MLS).结果视力MLS下降程度与P-VEP波幅,潜伏期变化呈正相关.高空间频率(0.770＞0.388＞0.194)刺激在AMD电生理诊断中异常检出率较高.结论视力、电生理学、视野等检查方法从不同侧面揭示出AMD视功能损害的程度,三种检查结果相关.多种检查方法联合应用有助于早期诊断AMD,电生理方法检查在AMD早期诊断中可通过改变刺激条件提高诊断的敏感性.     

课堂互动与实用型医学人才的成长

创新是一个国家生存和发展的灵魂,高等医学教育更是肩负着培养能适应时代要求具有创新能力的高素质医学人才的重任,医学教育方向不断创新,贯彻与时俱进的科学发展观势在必行,形势对教师素质和教学方法已提出了新的要求。1课堂互动的依据和观念随着成人继续教育的不断深化、广泛     

端粒酶抑制剂对葡萄膜黑色素瘤细胞生长的抑制作用

Objective To study the restrain effects of two telomerase inhibitors included IFN-α2b (interferon-α2b)and CDDP(cisplatin;cis-dichlorodiamine platinum)to uveal melanoma cells of human eyes,and to provide theory bases for chemotherary of uveal melanoma.Methods Applied IFN-α2b and CDDP to the primary cultured uveal melanoma cells of human eyes individually with different concentration and duration,and compared with control group.Morphological changes were observed by inverted optical and electronic microscope,and the restrain effects were detected by MTT.Results More and more morphological changes of restraint and apoptosis of cells were observed with the increasing concentration and duration of IFN-α 2b and CDDP.When action durations were 72 h.the cells were inhibited with the concentration more than 500 IU/ml(IFN-α 2b)and 1.00 mg/L(CDDP)respectively.The cells restrain rates were(66.1±4.7)%and(74.0+3.3)%with the concentration more than 5000 IU/ml(IFN-α2b)and 10 mg/L (CDDP),and the rates were higher than before(P<0.001).When concentrations were 5000 IU/ml(IFN-α2b)and 10.00 mg/L(CDDP),cells were inhibited at 48 h and the restrain rates were(67.9±8.1)%and(76.5±1.61%at 72 h,respectively,(P相似文献   

端粒酶抑制剂对葡萄膜黑色素瘤细胞生长的抑制作用

Objective To study the restrain effects of two telomerase inhibitors included IFN-α2b (interferon-α2b)and CDDP(cisplatin;cis-dichlorodiamine platinum)to uveal melanoma cells of human eyes,and to provide theory bases for chemotherary of uveal melanoma.Methods Applied IFN-α2b and CDDP to the primary cultured uveal melanoma cells of human eyes individually with different concentration and duration,and compared with control group.Morphological changes were observed by inverted optical and electronic microscope,and the restrain effects were detected by MTT.Results More and more morphological changes of restraint and apoptosis of cells were observed with the increasing concentration and duration of IFN-α 2b and CDDP.When action durations were 72 h.the cells were inhibited with the concentration more than 500 IU/ml(IFN-α 2b)and 1.00 mg/L(CDDP)respectively.The cells restrain rates were(66.1±4.7)%and(74.0+3.3)%with the concentration more than 5000 IU/ml(IFN-α2b)and 10 mg/L (CDDP),and the rates were higher than before(P<0.001).When concentrations were 5000 IU/ml(IFN-α2b)and 10.00 mg/L(CDDP),cells were inhibited at 48 h and the restrain rates were(67.9±8.1)%and(76.5±1.61%at 72 h,respectively,(P相似文献