上海市江宁街道20岁及以上人群干眼的流行病学调查

Objective To investigate the prevalence of dry eye in populations equal or over 20 years old in Jiangning District, Shanghai, China. Methods This was a cross-sectional study. From September 2008 to January 2009, 6 small districts including 21 102 people of Jiangning District were randomly selected as survey venues by Department of Ophthalmology in First People's Hospital affiliated to Shanghai Jiaotong University. Then, 1266 people as the selected residents were enrolled, which was figured out through the random cluster sampling procedure. Every participant completed dry eye questionnaire, the ocular surface disease index (OSDI), and a series of examination including slit-lamp microscope, tear-film break-up time (BUT), Schirmer Ⅰ test, and fluorescein staining of the cornea (F1). The diagnosis of dry eye was referred to the well-accepted domestic diagnostic criteria. The SPSS11.0 software was used to analyze the database, t test,χ2 test, one-way-ANOVA and Logistic regression were used for analysis. Results One thousand and eighty five residents finally took part in this study, and the inclusion ratio was 85.70%. Three hundred and twenty six individuals, including 101 men and 225 women, were diagnosed as dry eye, and the prevalence rate was 30.05%. The prevalence of dry eye in the female (33.78%) was higher than that of the male (24.11%) (χ2=11.46, P<0.01). The prevalence of dry eye in people over 50 years old was higher than that under 50 years (χ2=94.50, P<0.01). The figure of Schirmer Ⅰ test and BUT decreased in elder people, at the same time the scores of F1 and MGD increased. Meanwhile, the score of OSDI in dry eye patients was significantly higher than that in non-dry eye individuals. The relative risk factors of dry eye were gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs. Conclusions The prevalence of dry eye in female is higher than that in the male. And the prevalence of dry eye increases following the aging process. Relative risk factors of dry eye are gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs.     

上海市北新泾社区60岁及以上人群干眼的流行病学调查

目的 调查上海市北新泾社区60岁及以上人群干眼的患病情况,从而了解社区人群干眼的患病特征,更好地制定干眼的防治措施.方法 2008年1～5月对上海市北新泾社区60岁及以上人群作抽样调查,所有样本均进行问卷调查并进行裂隙灯、Schirmer I test、BUT、荧光素染色及DR-1干眼仪等检查.依据目前公认的国内干眼诊断标准进行诊断,并对其结果运用SPSS统计软件包进行分析处理.结果在800分问卷中,共746人参与答卷,应答率为93.25%.其中诊断为干眼者185例,男性65例,女性120例.并得出本课题社区调查对象中干眼的患病率为24.8%(185/746),男性患病率为22.0%,女性患病率为26.6%.全身疾病(高血压、糖尿病、冠心病、哮喘、过敏、吸烟)及用药可能促进干眼的发生. 结论 干眼是多因素导致的疾病,60岁及以上人群干眼的发病与老年人泪液分泌功能下降、睑板腺功能障碍有关.     

高浓度玻璃酸钠滴眼液治疗中重度干眼的临床研究

目的：观察高浓度玻璃酸钠滴眼液治疗中重度干眼的临床疗效。方法：中重度干眼患者40例随机分成试验组和对照组,每组各20例。试验组用玻璃酸钠滴眼液（3g/L）、对照组玻璃酸钠滴眼液（1g/L）联合重组人表皮生长因子滴眼液治疗,治疗前和治疗2wk后,通过症状评分、眼表疾病指数（OSDI）评分、泪膜破裂时间（BUT）、泪液分泌试验（Schirmer Ⅰ test,SⅠt）、角膜荧光素染色评分（FL）等评价两组疗效。结果：治疗前,两组各项指标差异均无统计学意义。治疗2wk后,除SⅠt外,两组的其他指标和治疗前相比,差异均有统计学意义; 两组间相比,除症状评分和OSDI差异有统计学意义,余无统计学差异。结论：高浓度玻璃酸钠滴眼液治疗中重度干眼,能有效缓解眼部不适症状,提高患者生存质量。     

上海市江宁街道20岁及以上人群干眼的流行病学调查

目的 探讨上海市江宁街道20岁及以上人群干眼的患病率及相关危险因素.方法 横断面研究方法.2008年9月至2009年1月期间,上海交通大学附属第一人民医院在江宁街道单纯随机抽取6个居委会作为调查点,对21102人≥20岁人群整群随机抽样,抽取调查对象1266人.所有受检者均接受干眼症状、体征及眼表疾病指数问卷调查.依据目前公认的国内干眼诊断标准进行诊断,采用t检验、卡方检验、One-Way-ANOVA方差分析法、Logistic回归分析法对数据结果进行统计分析.结果 共计1085人进入本次研究,应答率为85.70%.诊断为干眼的有326例,患病率为30.05%,其中男性患病率为24.11%,女性患病率为33.78%,女性高于男性(χ2=11.46,P<0.01).≥50岁人群干眼的患病率明显升高(χ2=94.50,P<0.01).随年龄增大泪液分泌实验、泪膜破裂时间表现为下降趋势,荧光素染色评分、睑板腺功能障碍的分级卜升.干眼患者的眼表疾病指数评分均高于无干眼者.与干眼相关的因素有性别、年龄、配戴角膜接触镜、长期滴用眼液及服用抗过敏药物.结论 在人群中,女性干眼患病率高于男性,随年龄增大干眼的患病率升高,其相关因素有性别、年龄、配戴角膜接触镜、长期滴用眼液及服用抗过敏药物.     

上海市江宁街道20岁及以上人群干眼的流行病学调查

Objective To investigate the prevalence of dry eye in populations equal or over 20 years old in Jiangning District, Shanghai, China. Methods This was a cross-sectional study. From September 2008 to January 2009, 6 small districts including 21 102 people of Jiangning District were randomly selected as survey venues by Department of Ophthalmology in First People's Hospital affiliated to Shanghai Jiaotong University. Then, 1266 people as the selected residents were enrolled, which was figured out through the random cluster sampling procedure. Every participant completed dry eye questionnaire, the ocular surface disease index (OSDI), and a series of examination including slit-lamp microscope, tear-film break-up time (BUT), Schirmer Ⅰ test, and fluorescein staining of the cornea (F1). The diagnosis of dry eye was referred to the well-accepted domestic diagnostic criteria. The SPSS11.0 software was used to analyze the database, t test,χ2 test, one-way-ANOVA and Logistic regression were used for analysis. Results One thousand and eighty five residents finally took part in this study, and the inclusion ratio was 85.70%. Three hundred and twenty six individuals, including 101 men and 225 women, were diagnosed as dry eye, and the prevalence rate was 30.05%. The prevalence of dry eye in the female (33.78%) was higher than that of the male (24.11%) (χ2=11.46, P<0.01). The prevalence of dry eye in people over 50 years old was higher than that under 50 years (χ2=94.50, P<0.01). The figure of Schirmer Ⅰ test and BUT decreased in elder people, at the same time the scores of F1 and MGD increased. Meanwhile, the score of OSDI in dry eye patients was significantly higher than that in non-dry eye individuals. The relative risk factors of dry eye were gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs. Conclusions The prevalence of dry eye in female is higher than that in the male. And the prevalence of dry eye increases following the aging process. Relative risk factors of dry eye are gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs.     

上海市江宁街道20岁及以上人群干眼的流行病学调查

Objective To investigate the prevalence of dry eye in populations equal or over 20 years old in Jiangning District, Shanghai, China. Methods This was a cross-sectional study. From September 2008 to January 2009, 6 small districts including 21 102 people of Jiangning District were randomly selected as survey venues by Department of Ophthalmology in First People's Hospital affiliated to Shanghai Jiaotong University. Then, 1266 people as the selected residents were enrolled, which was figured out through the random cluster sampling procedure. Every participant completed dry eye questionnaire, the ocular surface disease index (OSDI), and a series of examination including slit-lamp microscope, tear-film break-up time (BUT), Schirmer Ⅰ test, and fluorescein staining of the cornea (F1). The diagnosis of dry eye was referred to the well-accepted domestic diagnostic criteria. The SPSS11.0 software was used to analyze the database, t test,χ2 test, one-way-ANOVA and Logistic regression were used for analysis. Results One thousand and eighty five residents finally took part in this study, and the inclusion ratio was 85.70%. Three hundred and twenty six individuals, including 101 men and 225 women, were diagnosed as dry eye, and the prevalence rate was 30.05%. The prevalence of dry eye in the female (33.78%) was higher than that of the male (24.11%) (χ2=11.46, P<0.01). The prevalence of dry eye in people over 50 years old was higher than that under 50 years (χ2=94.50, P<0.01). The figure of Schirmer Ⅰ test and BUT decreased in elder people, at the same time the scores of F1 and MGD increased. Meanwhile, the score of OSDI in dry eye patients was significantly higher than that in non-dry eye individuals. The relative risk factors of dry eye were gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs. Conclusions The prevalence of dry eye in female is higher than that in the male. And the prevalence of dry eye increases following the aging process. Relative risk factors of dry eye are gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs.     

上海市江宁街道20岁及以上人群干眼的流行病学调查

Objective To investigate the prevalence of dry eye in populations equal or over 20 years old in Jiangning District, Shanghai, China. Methods This was a cross-sectional study. From September 2008 to January 2009, 6 small districts including 21 102 people of Jiangning District were randomly selected as survey venues by Department of Ophthalmology in First People's Hospital affiliated to Shanghai Jiaotong University. Then, 1266 people as the selected residents were enrolled, which was figured out through the random cluster sampling procedure. Every participant completed dry eye questionnaire, the ocular surface disease index (OSDI), and a series of examination including slit-lamp microscope, tear-film break-up time (BUT), Schirmer Ⅰ test, and fluorescein staining of the cornea (F1). The diagnosis of dry eye was referred to the well-accepted domestic diagnostic criteria. The SPSS11.0 software was used to analyze the database, t test,χ2 test, one-way-ANOVA and Logistic regression were used for analysis. Results One thousand and eighty five residents finally took part in this study, and the inclusion ratio was 85.70%. Three hundred and twenty six individuals, including 101 men and 225 women, were diagnosed as dry eye, and the prevalence rate was 30.05%. The prevalence of dry eye in the female (33.78%) was higher than that of the male (24.11%) (χ2=11.46, P<0.01). The prevalence of dry eye in people over 50 years old was higher than that under 50 years (χ2=94.50, P<0.01). The figure of Schirmer Ⅰ test and BUT decreased in elder people, at the same time the scores of F1 and MGD increased. Meanwhile, the score of OSDI in dry eye patients was significantly higher than that in non-dry eye individuals. The relative risk factors of dry eye were gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs. Conclusions The prevalence of dry eye in female is higher than that in the male. And the prevalence of dry eye increases following the aging process. Relative risk factors of dry eye are gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs.     

屈光性弱视儿童立体视功能储备的研究

目的 使用偏振分视的立体视模型探索屈光不正性弱视、屈光参差性弱视及正常儿童立体视功能储备情况,为防治儿童弱视提供依据.方法 选取2019年4月收治的68例屈光异常儿童,分为对照组(22例,44眼,屈光不正但矫正视力正常)、屈光不正组(25例,50眼,屈光不正性弱视)、屈光参差组(21例,21眼,屈光参差性弱视).使用双...     

上海市江宁街道20岁及以上人群干眼的流行病学调查

Objective To investigate the prevalence of dry eye in populations equal or over 20 years old in Jiangning District, Shanghai, China. Methods This was a cross-sectional study. From September 2008 to January 2009, 6 small districts including 21 102 people of Jiangning District were randomly selected as survey venues by Department of Ophthalmology in First People's Hospital affiliated to Shanghai Jiaotong University. Then, 1266 people as the selected residents were enrolled, which was figured out through the random cluster sampling procedure. Every participant completed dry eye questionnaire, the ocular surface disease index (OSDI), and a series of examination including slit-lamp microscope, tear-film break-up time (BUT), Schirmer Ⅰ test, and fluorescein staining of the cornea (F1). The diagnosis of dry eye was referred to the well-accepted domestic diagnostic criteria. The SPSS11.0 software was used to analyze the database, t test,χ2 test, one-way-ANOVA and Logistic regression were used for analysis. Results One thousand and eighty five residents finally took part in this study, and the inclusion ratio was 85.70%. Three hundred and twenty six individuals, including 101 men and 225 women, were diagnosed as dry eye, and the prevalence rate was 30.05%. The prevalence of dry eye in the female (33.78%) was higher than that of the male (24.11%) (χ2=11.46, P<0.01). The prevalence of dry eye in people over 50 years old was higher than that under 50 years (χ2=94.50, P<0.01). The figure of Schirmer Ⅰ test and BUT decreased in elder people, at the same time the scores of F1 and MGD increased. Meanwhile, the score of OSDI in dry eye patients was significantly higher than that in non-dry eye individuals. The relative risk factors of dry eye were gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs. Conclusions The prevalence of dry eye in female is higher than that in the male. And the prevalence of dry eye increases following the aging process. Relative risk factors of dry eye are gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs.     

上海市江宁街道20岁及以上人群干眼的流行病学调查

Objective To investigate the prevalence of dry eye in populations equal or over 20 years old in Jiangning District, Shanghai, China. Methods This was a cross-sectional study. From September 2008 to January 2009, 6 small districts including 21 102 people of Jiangning District were randomly selected as survey venues by Department of Ophthalmology in First People's Hospital affiliated to Shanghai Jiaotong University. Then, 1266 people as the selected residents were enrolled, which was figured out through the random cluster sampling procedure. Every participant completed dry eye questionnaire, the ocular surface disease index (OSDI), and a series of examination including slit-lamp microscope, tear-film break-up time (BUT), Schirmer Ⅰ test, and fluorescein staining of the cornea (F1). The diagnosis of dry eye was referred to the well-accepted domestic diagnostic criteria. The SPSS11.0 software was used to analyze the database, t test,χ2 test, one-way-ANOVA and Logistic regression were used for analysis. Results One thousand and eighty five residents finally took part in this study, and the inclusion ratio was 85.70%. Three hundred and twenty six individuals, including 101 men and 225 women, were diagnosed as dry eye, and the prevalence rate was 30.05%. The prevalence of dry eye in the female (33.78%) was higher than that of the male (24.11%) (χ2=11.46, P<0.01). The prevalence of dry eye in people over 50 years old was higher than that under 50 years (χ2=94.50, P<0.01). The figure of Schirmer Ⅰ test and BUT decreased in elder people, at the same time the scores of F1 and MGD increased. Meanwhile, the score of OSDI in dry eye patients was significantly higher than that in non-dry eye individuals. The relative risk factors of dry eye were gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs. Conclusions The prevalence of dry eye in female is higher than that in the male. And the prevalence of dry eye increases following the aging process. Relative risk factors of dry eye are gender, age, wearing contact lens, long-time using of eye solutions, taking anti-allergy drugs.