全文获取类型
收费全文 | 1066篇 |
免费 | 178篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 46篇 |
妇产科学 | 10篇 |
基础医学 | 43篇 |
口腔科学 | 10篇 |
临床医学 | 185篇 |
内科学 | 262篇 |
皮肤病学 | 30篇 |
神经病学 | 53篇 |
特种医学 | 87篇 |
外科学 | 175篇 |
综合类 | 51篇 |
现状与发展 | 20篇 |
一般理论 | 2篇 |
预防医学 | 73篇 |
眼科学 | 26篇 |
药学 | 23篇 |
中国医学 | 2篇 |
肿瘤学 | 148篇 |
出版年
2024年 | 7篇 |
2023年 | 42篇 |
2021年 | 21篇 |
2020年 | 23篇 |
2019年 | 10篇 |
2018年 | 54篇 |
2017年 | 48篇 |
2016年 | 38篇 |
2015年 | 41篇 |
2014年 | 42篇 |
2013年 | 63篇 |
2012年 | 22篇 |
2011年 | 38篇 |
2010年 | 57篇 |
2009年 | 67篇 |
2008年 | 41篇 |
2007年 | 32篇 |
2006年 | 36篇 |
2005年 | 24篇 |
2004年 | 24篇 |
2003年 | 17篇 |
2002年 | 19篇 |
2001年 | 22篇 |
2000年 | 21篇 |
1999年 | 29篇 |
1998年 | 33篇 |
1997年 | 32篇 |
1996年 | 46篇 |
1995年 | 32篇 |
1994年 | 20篇 |
1993年 | 22篇 |
1992年 | 16篇 |
1991年 | 21篇 |
1990年 | 13篇 |
1989年 | 15篇 |
1988年 | 22篇 |
1987年 | 21篇 |
1986年 | 17篇 |
1985年 | 14篇 |
1984年 | 6篇 |
1983年 | 7篇 |
1982年 | 11篇 |
1981年 | 5篇 |
1980年 | 5篇 |
1978年 | 12篇 |
1977年 | 8篇 |
1976年 | 7篇 |
1975年 | 5篇 |
1964年 | 5篇 |
1963年 | 4篇 |
排序方式: 共有1261条查询结果,搜索用时 15 毫秒
1.
Paul Wexberg MD BM Richard Pacher MD Suzanne Rdler MD Katharina Kiss MD Gilbert Beran MD Michael Grimm MD Gerald Maurer MD Dietmar Glogar MD FESC 《The Journal of heart and lung transplantation》2002,21(12):583-1263
BACKGROUND: Endothelin, a peptide with strong vasoconstrictive and mitogenic properties, has been found to increase after cardiac transplantation. We therefore assessed the association between its precursor peptide, big endothelin-1, and intimal hyperplasia and coronary flow reserve after heart transplantation. METHODS: Thirty-five patients without hemodynamically significant coronary artery disease after heart transplantation were investigated: Average peak flow velocity in the left anterior descending artery (LAD) was assessed by intracoronary Doppler at baseline as well as after injection of adenosine; coronary flow reserve was calculated as a ratio of both and was corrected for patient age and baseline average peak flow velocity. Lumen, intima + media and total vessel area were measured by intracoronary ultrasound. The plasma concentration of big endothelin-1 in venous blood was determined by radioimmunoassay. RESULTS: Patients with elevated big endothelin-1 levels (>2 fmol/ml) tended to have a decreased corrected coronary flow reserve (2.60 +/- 0.9 vs 3.21 +/- 1.0, p = 0.078). They also had a significantly larger intima + media area (5.82 +/- 2.9 vs 2.37 +/- 2.9 mm(2), p = 0.004) and total vessel area (18.36 +/- 5.8 vs 12.81 +/- 4.8 mm(2), p = 0.012) than those with normal plasma concentrations. CONCLUSIONS: Our study suggests an association between elevated big endothelin-1 plasma levels and the development of intimal hyperplasia and reduction of coronary flow reserve after cardiac transplantation. 相似文献
2.
3.
R H Curry P R Yarnold F B Bryant G J Martin R L Hughes 《Evaluation & the health professions》1988,11(1):113-129
The selection and subsequent performance of 212 internal medicine residents was examined by factor analysis and path analysis. A three-factor solution accounted for most of the variance among the nine selection variables. These three factors, labeled Board Scores, Faculty Evaluations, and Academic Distinction, were then combined with in-training residency performance evaluations and composite scores on the ABIM certifying examination to produce a comprehensive path model of house staff selection and performance. The Academic Distinction factor emerged as the strongest predictor of residency performance,; the Faculty Evaluations factor was also a significant component of the model. Standardized test scores correlated poorly with clinical performance. The data suggest that increased attention to the content of letters of reference could substantially improve their predictive validity. Other means of reporting subjective evaluations may also be needed to increase the stature of non-cognitive attributes in house staff selection decisions. 相似文献
4.
5.
6.
The computerized database system described was initially developed in 1986 to facilitate analysis of retrospective head and neck cancer data from the Royal Adelaide Hospital Department of Otolaryngology. This has now been expanded to become an on-going patient information management system. It is based on the dBase-III-Plus database package and is implemented on an IBM XT compatible computer. The system was designed to be used by staff without specialist computer skills and is therefore largely “menu-driven.” The main functions include patient record creation, update, and retrieval, and the production of reports including graphical presentations. There is also a powerful but easy to use query facility. The system has already provided much useful epidemiological material but is now beginning to fulfill an even more important role in patient follow-up and in assisting evaluation of alternative treatment protocols. 相似文献
7.
Mahadevaiah SK; Odorisio T; Elliott DJ; Rattigan A; Szot M; Laval SH; Washburn LL; McCarrey JR; Cattanach BM; Lovell-Badge R; Burgoyne PS 《Human molecular genetics》1998,7(4):715-727
An RNA-binding motif (RBM) gene family has been identified on the human Y
chromosome that maps to the same deletion interval as the 'azoospermia
factor' (AZF). We have identified the homologous gene family (Rbm) on the
mouse Y with a view to investigating the proposal that this gene family
plays a role in spermatogenesis. At least 25 and probably >50 copies of
Rbm are present on the mouse Y chromosome short arm located between Sry and
the centromere. As in the human, a role in spermatogenesis is indicated by
a germ cell-specific pattern of expression in the testis, but there are
distinct differences in the pattern of expression between the two species.
Mice carrying the deletion Yd1, that maps to the proximal Y short arm, are
female due to a position effect resulting in non-expression of Sry ;
sex-reversing such mice with an Sry transgene produces males with a high
incidence of abnormal sperm, making this the third deletion interval on the
mouse Y that affects some aspect of spermatogenesis. Most of the copies of
Rbm map to this deletion interval, and the Yd1males have markedly reduced
Rbm expression, suggesting that RBM deficiency may be responsible for, or
contribute to, the abnormal sperm development. In man, deletion of the
functional copies of RBM is associated with meiotic arrest rather than
sperm anomalies; however, the different effects of deletion are consistent
with the differences in expression between the two species.
相似文献
8.
9.
10.
Psychological androgyny and preference for intubation in a hypothetical case of end-stage lung disease 总被引:1,自引:0,他引:1
Psychological androgyny theory (PAT) was employed as a model of the interpersonal (social) and task activities required of physicians for care of their patients. According to PAT, individuals with a large repertoire of task and social skills ("androgynous" individuals) should be optimally adaptable to contingencies reflecting varying combinations of task and social challenges. The authors examined the relationship between androgyny and preference for intubation on a patient management problem involving end-stage lung disease for 67 general internists and internal medicine housestaff from two hospitals. Results revealed a negative relationship between androgyny and preference for intubation, suggesting that androgynous and nonandrogynous physicians respond differently to complex and difficult decision-making tasks. Indirect evidence is offered to suggest that this response reflects a general tendency to utilize fewer health care resources. Discussion focuses on the need to improve the precision of measurement of these latent constructs. 相似文献