全文获取类型
收费全文 | 1336篇 |
免费 | 67篇 |
国内免费 | 78篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 52篇 |
妇产科学 | 15篇 |
基础医学 | 160篇 |
口腔科学 | 16篇 |
临床医学 | 242篇 |
内科学 | 290篇 |
皮肤病学 | 24篇 |
神经病学 | 28篇 |
特种医学 | 287篇 |
外科学 | 96篇 |
综合类 | 28篇 |
预防医学 | 84篇 |
眼科学 | 5篇 |
药学 | 95篇 |
肿瘤学 | 54篇 |
出版年
2023年 | 5篇 |
2021年 | 5篇 |
2019年 | 10篇 |
2018年 | 11篇 |
2017年 | 11篇 |
2016年 | 17篇 |
2015年 | 19篇 |
2014年 | 23篇 |
2013年 | 33篇 |
2012年 | 58篇 |
2011年 | 37篇 |
2010年 | 43篇 |
2009年 | 46篇 |
2008年 | 40篇 |
2007年 | 105篇 |
2006年 | 28篇 |
2005年 | 46篇 |
2004年 | 31篇 |
2003年 | 35篇 |
2002年 | 27篇 |
2001年 | 28篇 |
2000年 | 31篇 |
1999年 | 25篇 |
1998年 | 73篇 |
1997年 | 72篇 |
1996年 | 57篇 |
1995年 | 64篇 |
1994年 | 36篇 |
1993年 | 37篇 |
1992年 | 23篇 |
1991年 | 22篇 |
1990年 | 22篇 |
1989年 | 41篇 |
1988年 | 39篇 |
1987年 | 27篇 |
1986年 | 28篇 |
1985年 | 43篇 |
1984年 | 26篇 |
1983年 | 14篇 |
1982年 | 28篇 |
1981年 | 14篇 |
1980年 | 24篇 |
1979年 | 7篇 |
1978年 | 6篇 |
1977年 | 16篇 |
1976年 | 17篇 |
1975年 | 11篇 |
1972年 | 6篇 |
1971年 | 3篇 |
1966年 | 2篇 |
排序方式: 共有1481条查询结果,搜索用时 15 毫秒
1.
Extravesical versus Leadbetter-Politano ureteroneocystostomy: a comparison of urological complications in 320 renal transplants 总被引:3,自引:0,他引:3
The urological complications of 320 consecutive renal transplants performed at our institution between October 17, 1985 and November 10, 1989 are reviewed. The Leadbetter-Politano technique of ureteroneocystostomy was used in the first 160 patients (group 1) and an anterior extravesical technique modified from the methods of Witzel, Sampson and Lich was performed in the second 160 patients (group 2). Urological complications occurred in 15 patients (9.4%) in group 1 and 6 (3.7%) in group 2 (p = 0.04). Ureterovesical junction obstruction occurred in 6 patients (3.7%) in group 1 and 1 (0.6%) in group 2 (p = 0.05). Complications of leakage, ureteral necrosis and ureteral stricture were comparable in the 2 groups. Therefore, we advocate the use of the anterior extravesical technique over Leadbetter-Politano ureteral reimplantation based on the lower incidence of urological complications and various technical advantages, including less operative time, avoidance of a separate cystotomy, less hematuria and ability to use short donor ureters. 相似文献
2.
We report 2 cases of leiomyosarcoma of the bladder that occurred after long-term cyclophosphamide chemotherapy for lupus nephritis and rheumatoid arthritis. One patient had a tumor at the end of an 11-year course of chemotherapy and 1 approximately 7 years after completing a 7-year course of chemotherapy. Patient 1 underwent left partial cystectomy and patient 2 underwent cystectomy with ileal conduit urinary diversion. In patient 1 the tumor was a typical leiomyosarcoma and patient 2 had a myxoid variant. Both patients were free of disease at 4 months and 3 years, respectively. Whereas previous reports of the carcinogenic effects of cyclophosphamide have been questioned, since the induced tumors occurred in patients being treated for other neoplasms (lymphoproliferative and myeloproliferative disorders), the disease in both of our patients followed cyclophosphamide therapy for nonneoplastic disorders. 相似文献
3.
D. Chemla P. Démolis M. Thyrault D. Annane Y. Lecarpentier and JF Giudicelli 《Fundamental & clinical pharmacology》1996,10(4):393-399
Summary— The influence of local resistance and cardiac performance on peripheral blood acceleration was investigated in 14 healthy male volunteers. Steady and pulsatile flow was studied in the brachial and in the common carotid arteries, ie, two territories that exhibit marked differences in resistive characteristics. Instantaneous blood velocity (V), mean blood velocity (Vm ) and artery diameter (D) were evaluated at rest by an ultrasonic range-gated pulsed Doppler flowmeter using a double transducer probe, thus allowing the calculation of mean blood flow (Q). Mean local resistance (R) was obtained by dividing the mean arterial pressure by Q. The peak value of the local acceleration of the blood was obtained by computer-assisted calculation of the first derivative of instantaneous blood velocity (Gmax = +dV/dtmax ). Peak aortic blood acceleration (GAo) was simultaneously measured from the suprasternal notch using a pulsed Doppler velocity meter. In the brachial and the common carotid arteries, Gmax was of a similar magnitude (551 ±30 and 555 ± 44 cm/s2 , respectively) despite major differences in the respective D, Vm , Q and R values. In neither artery was there a relationship between Gmax and either resting Q or R. At the brachial artery level, Gmax was positively related to GAo ( r = 0.79, P = 0.0008). At the common carotid artery level, there was a weak, although non significant relationship between Gmax and GAo ( P = 0.08). Our results indicate that the local acceleration of peripheral blood flow in the brachial artery is related rather to upstream central impulse than to downstream hemodynamics, and suggest some regional differences in the hemodynamic determinants of the local acceleration of peripheral blood flow. 相似文献
4.
J C Mason K S Ordelheide G M Grames T V Thrasher R D Harris R H Bui M C Mackett 《Transplantation》1987,44(4):588-591
5.
6.
Whereas water loss in land living animals occurs continuously, water intake takes place discontinuously. At the normal operating set point of plasma osmolality, urine is more concentrated than plasma due to secretion of vasopressin. Thus animals operate around a state of mild dehydration. As water loss occurs, the severity of dehydration and thirst increase in intensity and at some point water intake occurs. Sufficient water is consumed to return plasma osmolality to the normal operating set point. Food intake and water balance are interdependent as food provides the osmoles which determine obligatory renal solute excretion. When dry food with the same osmotic content was substituted for canned food (water content 74%), dogs increased water intake from 24.2 +/- 4.3 to 62.2 +/- 8.8 ml/kg. Urine output and urine osmolality were unchanged, as under conditions of normal hydration, near maximal urine concentration is achieved. Changing water intake is the only available variable to maintain water balance. During water deprivation, the major renal mechanism appears to be natriuresis. In rehydration, satiety mechanisms ensure appropriate water intake and renal sodium conservation restores sodium balance. 相似文献
7.
8.
Application of reflectance spectroscopy to the estimation of uric acid, urea and glucose: an evaluation of the Ames Seralyzer 下载免费PDF全文
An original approach to the measurement of analytes in clinical chemistry has now become available, in which dry reagent strip technology is linked to measurement by reflectance spectroscopy. The present studies have evaluated the performance of the first of these test systems—for uric acid, urea and glucose, in serum—by comparison with conventional liquid chemistry methods. Satisfactory performance in terms of both precision and accuracy was obtained for all three test systems, the current “state-of-the-art” performance criteria being met; the Seralyzer system proved reliable and easy to use in the hands of trained operators. It should find a place as a “Stat” analyser in the laboratory, in specified wards and in Health Centres. 相似文献
9.
10.
Influence of co-culture with established human endometrial epithelial and stromal cell lines on sperm movement characteristics 总被引:2,自引:0,他引:2
The effects of co-culture of human spermatozoa with human immortalized
endometrial cells - epithelial or stromal - on sperm movement
characteristics, including hyperactivation, were studied using computer-
assisted sperm analysis (CASA). Epithelial and stromal cell types could be
separated following 8-10 days of culture of endometrial cells originating
from human biopsies. Both cell types were immortalized by the SV 40 large T
antigen. Co-incubation of sperm with epithelial and stromal monolayers
enhanced the rate of hyperactivation: 24.9% (P <0.05) and 17.8% (P =
0.05) versus 9.5% as control, respectively, whereas the majority of
motility parameters remained unchanged. Conditioned media had no effect
upon sperm parameters, including hyperactivation. Co-incubation with either
monolayer was able to maintain sperm motility over a longer period than
incubation in control medium alone. In four patients whose spermatozoa did
not exhibit hyperactivation, co-incubation with epithelial cells, but not
conditioned medium, allowed normal rates of hyperactivation (range: 6.9-
15.6%).
相似文献