全文获取类型
收费全文 | 770篇 |
免费 | 76篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 44篇 |
妇产科学 | 19篇 |
基础医学 | 87篇 |
口腔科学 | 104篇 |
临床医学 | 86篇 |
内科学 | 95篇 |
皮肤病学 | 9篇 |
神经病学 | 38篇 |
特种医学 | 158篇 |
外科学 | 78篇 |
综合类 | 22篇 |
预防医学 | 55篇 |
眼科学 | 1篇 |
药学 | 42篇 |
1篇 | |
肿瘤学 | 15篇 |
出版年
2021年 | 9篇 |
2019年 | 3篇 |
2018年 | 13篇 |
2017年 | 9篇 |
2016年 | 11篇 |
2015年 | 10篇 |
2014年 | 9篇 |
2013年 | 19篇 |
2012年 | 24篇 |
2011年 | 17篇 |
2010年 | 11篇 |
2009年 | 24篇 |
2008年 | 25篇 |
2007年 | 33篇 |
2006年 | 36篇 |
2005年 | 23篇 |
2004年 | 27篇 |
2003年 | 13篇 |
2002年 | 20篇 |
2001年 | 16篇 |
2000年 | 17篇 |
1999年 | 26篇 |
1998年 | 24篇 |
1997年 | 20篇 |
1996年 | 30篇 |
1995年 | 21篇 |
1994年 | 24篇 |
1993年 | 21篇 |
1992年 | 19篇 |
1991年 | 24篇 |
1990年 | 19篇 |
1989年 | 34篇 |
1988年 | 26篇 |
1987年 | 23篇 |
1986年 | 17篇 |
1985年 | 17篇 |
1984年 | 14篇 |
1983年 | 15篇 |
1982年 | 12篇 |
1981年 | 10篇 |
1980年 | 9篇 |
1979年 | 16篇 |
1977年 | 9篇 |
1976年 | 11篇 |
1975年 | 6篇 |
1973年 | 3篇 |
1971年 | 6篇 |
1970年 | 5篇 |
1969年 | 3篇 |
1961年 | 3篇 |
排序方式: 共有856条查询结果,搜索用时 15 毫秒
1.
Pressure ulcers are a high-risk, high-volume, and high-cost problem for persons with disabilities. This article describes four tools published in the literature and reports the validity, reliability, strengths, and limitations of each. These tools include the Pressure Ulcer Scale for Healing (PUSH), the Pressure Sore Status Tool (PSST), the Sussman Wound Healing Tool (SWHT), and the Sessing Scale. Rehabilitation nurses should use a consistent framework with accurate quantification to assess, document, and monitor changes in pressure ulcers over time. Such a measurement tool must prove valid for the disabled population in which the tool is used. This will enable healthcare providers to communicate more effectively and evaluate the therapeutic plan of care. 相似文献
2.
3.
进一步研究了抗三尖杉酯碱的HL-60细胞(HR20)抗细胞凋亡的机制及该抗性和抗药性的关系。结果表明,环孢菌素A(CsA)20,10μg·ml ̄(-1)诱导HL-60细胞发生凋亡,而阻断HR20细胞于G_1期,就不能诱导细胞发生凋亡。低浓度的CsA明显增加柔红霉素在HR20细胞内的积聚,其逆转抗药性作用与阻断细胞周期运行无关。CsA10μg·ml ̄(-1)处理HR20细胞,可引起50kDa的蛋白质高度磷酸化。结果提示:环孢菌素A阻断抗三尖杉酯碱的HL-60细胞于G_1期,而诱导敏感的HL-60细胞发生凋亡,其阻断作用与抗药性无关 相似文献
4.
Headaches in civil servants: effect on work and leisure 总被引:1,自引:0,他引:1
Headaches in a group of civil servants and their effects on work and leisure activities, the medication taken, and numbers consulting their general practitioners during a year were assessed by a self administered questionnaire sent to 1000 civil servants in sections of a government department in London. The response rate was 74.7%. Altogether 77% of the respondents reported having had headaches in the previous 12 months. There was a higher prevalence in women (88%) than men (70%) and a significant decrease with increasing age. Women also had more frequent and severe headaches than men: 34% reported that headaches had interfered with work, either by impaired performance, making them leave work early, or by stopping them coming into work. About half of those who reported having severe headaches denied that they had affected their work, indicating difficulty in interpreting the term "severe." Nevertheless, 22% said that headaches interfered with their leisure activities as well as work which may be regarded as further evidence that the condition was truly disabling. Eighty per cent of those with headaches took medication, but within the past year only 11% had consulted their general practitioner and only 2.2% had been referred for further specialist opinion. Of the 22% who had not had a headache during the previous 12 months, 5.6% had never had a headache. In this group there was a larger proportion of men, a higher proportion with increasing age, and a higher proportion in non-desk working grades. Differentiation of the causes of headaches was not attempted in this survey but it is concluded that the extent to which they interfere with work and leisure is an important guide to their severity. It is suggested that the occupational health services may have an important role in assessing the causes of headaches and instituting preventive measures that benefit both the worker and industry. 相似文献
5.
Hydrolysis of peptides within lumen of small intestine 总被引:2,自引:0,他引:2
6.
The effect of source encapsulation on the energy spectra of 192Ir and 137Cs seed sources, both with stainless steel and with platinum encapsulation, was determined from results of Monte Carlo simulation. The fractional scatter dose around these sources has also been determined from Monte Carlo simulation. The platinum-encapsulated 192Ir source exhibited greater attenuation of the primary spectrum, as expected, and, consistent with this greater attenuation, exhibited more scattered radiation. Significantly less scatter was seen with the 137Cs source than with either 192Ir source, as is consistent with the higher-energy photons from 137Cs. 相似文献
7.
Summary The relationships of VII and VIII cranial nerves and related arteries are reviewed in 26 preparations by microdissection techniques. These vessels may be grouped in large (AICA, PICA), medium (LA, SA, CSA, RPI) and small calibre (vasa nervorum, radicullar and medullar branches). The importance of these structures in acoustic neuroma surgery, vestibular neurectomy and cross-compression syndromes is discussed. Vascular loops and elongated arteries are normal structures present at birth.This work was supported by a grant from the AJ Roemmers Foundation 相似文献
8.
Differential pattern of DNA-aneuploidy in human malignancies 总被引:5,自引:0,他引:5
Th Büchner W Hiddemann B Wörmann B Kleinemeier J Schumann W Göhde J Ritter K.-M Müller DB von Bassewitz A Roessner E Grundmann 《Pathology, research and practice》1985,179(3):310-317
The differential pattern of DNA-aneuploidy, detected by flow cytometry (FCM) regarding its frequency, grade and multiclonality, was investigated and correlated to tumor type, malignancy grade, tumor stage and prognosis in a multi-institutional study at the University of Münster. High resolution measurements using admixed normal blood reference cells were undertaken in 2413 cases of 13 different malignant diseases and in 776 benign lesions or samples. The incidence of DNA-aneuploidy was highest in melanomas, carcinomas, testicular tumors, sarcomas (75%-95%) and myelomas (65%). Acute leukemias showed an intermediate DNA-aneuploidy rate of 40% with special subgroups represented by common ALL (44%), p less than 0.05) and myelomonocytic/monocytic AML (47%, p less than 0.01). The lowest DNA-aneuploidy-rate was found in basal cell skin carcinomas (19%) and congenital melanocytic nevi (9%). No case of DNA-aneuploidy was observed in the 776 benign lesions or samples.--DNA-indices giving the grade of DNA-aneuploidy with 1.0 for normal diploid G1/0 cells were found distributed predominantly between 1.0 and 2.0 in the solid tumors, except testicular tumors, clustering around a triploid maximum at 1.5. DNA-indices of myelomas and acute leukemias generally ranged below 1.25 with lower DNA-aneuploidy grades in AML than in ALL (p less than 0.01).--In melanomas the aneuploidy rate was higher (86%) in metastases than in the primary tumors (54%, p = 0.001).(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
9.
Comparison of Diamond''s medium modified and Kupferberg medium for detection of Trichomonas vaginalis.
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
S M Gelbart J L Thomason P J Osypowski J A James P R Hamilton 《Journal of clinical microbiology》1989,27(5):1095-1096
Diamond's medium modified, the commercially available version of the Klaas modification of Diamond's medium, was compared to Kupferberg medium and to direct wet-mount examination for detection of trichomonads in symptomatic patients. Diamond's medium was found to be superior to both Kupferberg medium (P less than 10(-4) and wet mount (P less than 10(-6]. 相似文献
10.
C Borrás M M Liss C Thomason O Hidalgo-Salvatierra C P White J E Barton 《Health physics》1987,53(6):631-637
As part of a U.S. multi-regional pilot study conducted by the six Centers for Radiological Physics, 12-mm-diameter by 0.4-mm-thick CaSO4:Dy Teflon-embedded discs were evaluated and used to measure patient entrance exposure on 60 "average" patients at 12 clinical centers. The discs were found to have adequate sensitivity, reproducibility and linearity up to 69.7 microC kg-1 (270 mR). The minimum measurable exposure was estimated as 0.4 microC kg-1 (1.5 mR). All responses were corrected for energy dependence, which varied +/- 20% from 1.7 to 6.5 mm Al half-value layer. Patient entrance exposure values ranged from 1.3 to 28 microC kg-1 (5 to 110 mR), with a median value of 5.2 microC kg-1 (20 mR). This value agreed with exposure measurements made on the chest radiography equipment using an ionization chamber and a phantom which simulated an "average" patient, and with published Nationwide Evaluation of X-Ray Trends (NEXT) data for the same period. 相似文献