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1.
Marie Tassy Alison L. Eldridge Rasaki A. Sanusi Oluwaseun Ariyo AnuOluwapo Ogundero Tolu E. Eyinla Dantong Wang 《Nutrients》2021,13(6)
The paucity of adequate data on dietary and nutrient intakes of school-age children is a barrier to addressing malnutrition and associated risks in Nigeria. This study included 955 children aged 4–13 years from Ibadan, Nigeria, using a stratified random sampling design. Information on family socio-demographic characteristics was reported, and child anthropometrics were measured. Dietary intake data were collected using a multi-pass 24 h dietary recall method; 20% of subjects completed a second 24 h recall to estimate usual nutrient intakes. Means and distributions of usual intakes of energy and nutrients as well as prevalence of inadequacy were estimated. Usual energy intake (kcal/day) was 1345 and 1590 for younger (4–8 years) and older (9–13 years) age groups, respectively. The macronutrient intakes of most children did not conform to Adequate Macronutrient Distribution Ranges (AMDRs), which were characterized by a higher proportion of energy from carbohydrates and lower proportion from total fats. Protein intake was largely within the AMDR. Compared to recommendations, over 60% of 4–8-year-old children had inadequate intakes of calcium, copper, iron, folate, and vitamins A, D, and E. There were more micronutrient inadequacies in the older children. This study identifies nutrition gaps and suggests future research and education to improve child nutrition in Nigeria. 相似文献
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Racial and Ethnic Disparities in Graft and Recipient Survival in Elderly Kidney Transplant Recipients
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Christopher R. Lane Susan LeBaigue Oluwaseun B. Esan Adedoyin A. Awofisyo Natalie L. Adams Ian S.T. Fisher Kathie A. Grant Tansy M. Peters Lesley Larkin Robert H. Davies Goutam K. Adak 《Emerging infectious diseases》2014,20(7):1097-1104
In England and Wales, the emergence of Salmonella enterica serovar Enteritidis resulted in the largest and most persistent epidemic of foodborne infection attributable to a single subtype of any pathogen since systematic national microbiological surveillance was established. We reviewed 67 years of surveillance data to examine the features, underlying causes, and overall effects of S. enterica ser. Enteritidis. The epidemic was associated with the consumption of contaminated chicken meat and eggs, and a decline in the number of infections began after the adoption of vaccination and other measures in production and distribution of chicken meat and eggs. We estimate that >525,000 persons became ill during the course of the epidemic, which caused a total of 6,750,000 days of illness, 27,000 hospitalizations, and 2,000 deaths. Measures undertaken to control the epidemic have resulted in a major reduction in foodborne disease in England and Wales. 相似文献
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Olubukola T. Oyebode Oluwaseun R. Adebiyi Olufunso O. Olorunsogo 《Toxicology mechanisms and methods》2019,29(2):128-137
Ciprofloxacin (CIP) and Amoxycillin/Clavulanate (AC) are broad-spectrum antibiotics that are commonly administered for treatment of various bacterial infections. Studies have reported the antiproliferative and apoptotic activities of CIP in several cancer cell lines while AC has been implicated in drug–induced liver injury. We investigated the influence of CIP and AC on mitochondrial Permeability Transition (mPT) pore, ATPase activity, and cytochrome C release of normal Rat Liver Mitochondria (RLM) spectrophotometrically. In vitro, CIP and AC induced the opening of the mPT pore in a concentration-dependent manner with evidence of cytochrome C release maximally at 70?µg/ml by 13 and 10 folds, respectively. In vivo, CIP (100, 200?mg/kgbw) significantly induced mPT pore opening with induction folds of 2.4 and 2.6, respectively. However, low dose of AC (10?mg/kgbw) had no effect whatsoever on the mPT pore while higher dose (30?mg/kgbw) significantly induced pore opening by 3.4 folds. Similarly, CIP(100?mg/kgbw) and AC (30?mg/kgbw), significantly enhanced RLM ATPase activity, induced cytochrome C release and increased levels of RLM malondialdehyde generation and triggered the activation of caspases-9 and 3 in liver post-mitochondrial fraction. There were also significant (p<0.05) elevation in levels of serum aminotransferases and white blood cell count. Our results show that prolonged use of Ciprofloxacin and Amoxicillin Clavulanate could result in mitochondrial membrane breakdown via induction of opening of mPT pore leading to expulsion of cytochrome C, lipid peroxidation and decrease in energy content in healthy liver cells. These drugs should therefore be used with caution. 相似文献
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Nouchine Hadjikhani MD PhD Daniel S. Albrecht PhD Caterina Mainero MD PhD Eri Ichijo MS Noreen Ward MS Cristina Granziera MD PhD Nicole R. Zürcher PhD Oluwaseun Akeju MD Guillaume Bonnier PhD Julie Price PhD Jacob M. Hooker PhD Vitaly Napadow PhD Matthias Nahrendorf MD PhD Marco L. Loggia PhD Michael A. Moskowitz MD 《Annals of neurology》2020,87(6):939-949
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Temitope O Keku Robert S Sandler James G Simmons Joseph Galanko John T Woosley Michelle Proffitt Oluwaseun Omofoye Maya McDoom Pauline K Lund 《BMC cancer》2008,8(1):143