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排序方式: 共有131条查询结果,搜索用时 31 毫秒
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Yoshino I Nakanishi R Kodate M Osaki T Hanagiri T Takenoyama M Yamashita T Imoto H Taga S Yasumoto K 《International surgery》2000,85(2):105-112
BACKGROUND AND OBJECTIVES: We have retrospectively analyzed the postoperative prognostic factors for 116 patients with stage I adenocarcinoma, with special reference to pleural retraction and intra-tumoral air-bronchogram imaged by computed tomography, which may represent the biological features of pulmonary adenocarcinoma for the retraction of surrounding tissues due to central necrosis and air space-lining growth, respectively. METHODS: The subgroups divided according to the presence of pleural retraction and/or intra-tumoral air-bronchogram on pre-operative CT were compared with respect to the postoperative disease-free survival (DFS) and other clinico-pathological factors. RESULTS: The rates of DFS at 5 years associated with 61 patients with pleural retraction and with 55 patients without pleural retraction were 64.4% and 91.3%, respectively (P = 0.0052), and those associated with 83 patients with air-bronchogram-positive tumors and with 33 patients with air-bronchogram-negative tumors were 81.8% and 64.8%, respectively (P = 0.0040). The DFS at 5 years associated with T1 (73 patients) and T2 (43 patients) were 83.6% and 64.3%, respectively (P = 0.0153). The Cox proportional hazards model analysis revealed that the presence of pleural retraction and the absence of air-bronchogram were independent factors for poor prognosis with relative risks of 7.8 and 5.1, respectively. Pathological T factor was also a significant prognostic factor with a relative risk of 3.2. Seventeen patients with pleural retraction-positive and air-bronchogram-negative tumors showed the high recurrence rate of 47.5% and a poor prognosis with DFS at 5 years of 35.1%. CONCLUSION: These results suggested that, in stage I adenocarcinoma, the degree of malignant potential may be well figured by radiological imaging, with a significant affect on susceptibility of recurrence following complete resection. 相似文献
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Shin-ichi Nunoda M.D. Naonori Mimo M.D. Hirotsugu Kitano M.D. Masanori Kyoi M.D. Senshu Hifumi M.D. Toshio Ueno M.D. Ryoyu Takeda M.D. Yasuni Nakanuraa M.D. 《The American journal of gastroenterology》1983,78(5):301-304
We describe a case of hepatocellular carcinoma in a 16-year-old boy whose mother, aunts, uncles, and cousins had liver dysfunction associated with HBs-Ag. Postmortem examination in this case revealed a hepatocellular carcinoma with a trabecular and partially pseudoglandular pattern involving the whole left and most of the right lobe, associated with liver cirrhosis of the postnecrotic type. Postmortem examination of the liver revealed numerous HBs-Ag positive hepatocytes demonstrated by Orcein staining in the nontumorous cirrhotic area, but not in the tumorous hepatocytes. Vertical transmission of HBV from his mother to the patient was suspected, and autopsy findings revealed continuous infection of HBV. Hepatocellular carcinoma in a young patient, especially when associated with HBs-Ag positive liver cirrhosis, as described here is rare in the English and Japanese literature. 相似文献
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Nobuki Shioya Nozomu Inoue Naonori Kawashima Yuki Tsukamoto Miyabi Nakayama Koji Hazama Yasuo Shichinohe Fumiyuki Suzuki Naotake Honma 《Internal medicine (Tokyo, Japan)》2021,60(1):91
As an intrathoracic goiter expands, it causes airway stenosis and phrenic nerve paralysis, and slight respiratory stimuli can trigger sudden life-threatening hypoventilation. A 78-year-old obese woman with a large intrathoracic goiter was found unconscious with agonal breathing in her room early in the morning. Cardiopulmonary resuscitation restored spontaneous circulation. She underwent surgical removal of the goiter; however, she required long-term mechanical ventilation because of atelectasis due to phrenic nerve paralysis. In patients with large intrathoracic goiters, difficulty breathing on exertion and diaphragm elevation on chest X-ray may be significant findings predicting future respiratory failure. 相似文献
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Yasunobu Nohara Eiko Kai Partha Pratim Ghosh Rafiqul Islam Ashir Ahmed Masahiro Kuroda Sozo Inoue Tatsuo Hiramatsu Michio Kimura Shuji Shimizu Kunihisa Kobayashi Yukino Baba Hisashi Kashima Koji Tsuda Masashi Sugiyama Mathieu Blondel Naonori Ueda Masaru Kitsuregawa Naoki Nakashima 《Journal of medical Internet research》2015,17(1)
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Matsumoto Yorihiko Fukushima Satsuki Shimahara Yusuke Kawamoto Naonori Tadokoro Naoki Kuroda Kensuke Nakajima Seiko Watanabe Takuya Seguchi Osamu Yanase Masanobu Fukushima Norihide Shimizu Hideyuki Kobayashi Junjiro Fujita Tomoyuki 《Journal of artificial organs》2020,23(1):19-26
Journal of Artificial Organs - Hemolysis is closely related with pump thrombosis and thromboembolic events in patients with continuous flow left ventricular assist devices. We retrospectively... 相似文献
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Hiromi Kubagawa Satoshi Oka Yoshiki Kubagawa Ikuko Torii Eiji Takayama Dong-Won Kang Dewitt Jones Naonori Nishida Toshio Miyawaki Luigi F. Bertoli Sheila K. Sanders Kazuhito Honjo 《Journal of clinical immunology》2014,34(1):35-45
IgM exists as both a monomer on the surface of B cells and a pentamer secreted by plasma cells. Both pre-immune “natural” and antigen-induced “immune” IgM antibodies are important for protective immunity and for immune regulation of autoimmune processes by recognizing pathogens and self-antigens. Effector proteins interacting with the Fc portion of IgM, such as complement and complement receptors, have thus far been proposed but fail to fully account for the IgM-mediated protection and regulation. A major reason for this deficit in our understanding of IgM function seems to be lack of data on a long elusive Fc receptor for IgM (FcμR). We have recently identified a bona fide FcμR in both humans and mice. In this article we briefly review what we have learned so far about FcμR. 相似文献
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Tomoyuki Fujita Takashi Kakuta Naonori Kawamoto Yusuke Shimahara Shin Yajima Naoki Tadokoro Soichiro Kitamura Junjiro Kobayashi Satsuki Fukushima 《Interactive Cardiovascular and Thoracic Surgery》2021,32(3):417
OBJECTIVESTo determine whether robotic mitral valve repair can be applied to more complex lesions compared with minimally invasive direct mitral valve repair through a right thoracotomy. Open in a separate windowMETHODSWe enrolled 335 patients over a 9-year period; 95% of the robotic surgeries were performed after experience performing direct mitral valve repair.RESULTSThe mean age in the robotic versus thoracotomy repair groups was 61 ± 14 vs 55 ± 11 years, respectively (P < 0.001); 97% vs 100% of the patients, respectively, had degenerative aetiologies. Repair complexity was simple in 106 (63%) vs 140 (84%), complex in 34 (20%) vs 20 (12%) and most complex in 29 (17%) vs 6 (4%) patients undergoing robotic versus thoracotomy repair, respectively. The average complexity score with robotic repair was significantly higher versus thoracotomy repair (P < 0.001). The robotic group underwent more chordal replacement using polytetrafluoroethylene and less resections. All patients underwent ring annuloplasty. Cross-clamp time did not differ between the groups, and no strokes or deaths occurred. More patients undergoing robotic repair underwent concomitant procedures versus the thoracotomy group (30% vs 14%, respectively; P < 0.001). The overall repair rate was 100%, with no early mortality or strokes in either group. Postoperative mean residual mitral regurgitation was 0.3 in both groups, and the mean pressure gradient through the mitral valve was 2.4 vs 2.7 mmHg (robotic versus thoracotomy repair, respectively; P = 0.031).CONCLUSIONSRobotic surgery can be applied to repair more complex mitral lesions, with excellent early outcomes. 相似文献
10.
Yoshihiro Ohashi Yoshiaki Nakai Koichi Kuroki Junko Nakata Kenichi Maruoka Hiroshi Ikeoka Naonori Takeichi Shoko Kihara 《European archives of oto-rhino-laryngology》1985,241(2):169-174
Summary In the present study, the in vitro tissue-radioallergosorbent test (t-RAST) was performed in two groups of patients: one with perennial attacks of sneezing, serous hypersecretion and nasal congestion, the other with nasal congestion only. The results obtained were compared with those obtained by a series of conventional allergy tests. We then found that t-RAST provided objective data comparable to those obtained with serum-RAST and that the t-RAST is a reliable means of quantitatively detecting specific IgE antibodies in the nasal mucosa. t-RAST is of special value to diagnosticians because it is able to discern unequivocally and easily those patients with localized nasal allergy. 相似文献