全文获取类型
收费全文 | 1456篇 |
免费 | 142篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 81篇 |
妇产科学 | 13篇 |
基础医学 | 140篇 |
口腔科学 | 32篇 |
临床医学 | 141篇 |
内科学 | 371篇 |
皮肤病学 | 21篇 |
神经病学 | 66篇 |
特种医学 | 247篇 |
外科学 | 132篇 |
综合类 | 100篇 |
预防医学 | 133篇 |
眼科学 | 21篇 |
药学 | 51篇 |
中国医学 | 9篇 |
肿瘤学 | 38篇 |
出版年
2019年 | 11篇 |
2018年 | 13篇 |
2017年 | 10篇 |
2015年 | 21篇 |
2014年 | 41篇 |
2013年 | 69篇 |
2012年 | 40篇 |
2011年 | 36篇 |
2010年 | 42篇 |
2009年 | 65篇 |
2008年 | 38篇 |
2007年 | 57篇 |
2006年 | 37篇 |
2005年 | 37篇 |
2004年 | 24篇 |
2003年 | 31篇 |
2002年 | 25篇 |
2001年 | 20篇 |
2000年 | 19篇 |
1999年 | 21篇 |
1998年 | 81篇 |
1997年 | 57篇 |
1996年 | 64篇 |
1995年 | 44篇 |
1994年 | 50篇 |
1993年 | 44篇 |
1992年 | 13篇 |
1991年 | 10篇 |
1990年 | 20篇 |
1989年 | 49篇 |
1988年 | 43篇 |
1987年 | 36篇 |
1986年 | 25篇 |
1985年 | 22篇 |
1984年 | 23篇 |
1983年 | 21篇 |
1982年 | 22篇 |
1981年 | 24篇 |
1980年 | 20篇 |
1979年 | 22篇 |
1978年 | 13篇 |
1977年 | 31篇 |
1976年 | 19篇 |
1975年 | 19篇 |
1974年 | 12篇 |
1973年 | 21篇 |
1970年 | 15篇 |
1968年 | 18篇 |
1967年 | 10篇 |
1966年 | 13篇 |
排序方式: 共有1607条查询结果,搜索用时 0 毫秒
1.
APACHE II score and abdominal sepsis. A prospective study 总被引:7,自引:0,他引:7
J M Bohnen R A Mustard S E Oxholm B D Schouten 《Archives of surgery (Chicago, Ill. : 1960)》1988,123(2):225-229
Therapeutic trials for intra-abdominal sepsis require pretreatment stratification; physiologic scoring has been recently proposed for this purpose. We have prospectively tested the validity of one such scoring system, namely, the Acute Physiology and Chronic Health Evaluation (APACHE II). As part of a larger database, we correlated APACHE II scores with mortality in 100 patients hospitalized for generalized peritonitis or abdominal abscess. Use of steroids was recorded because of our suspicion that steroids increase mortality but blunt the physiologic response to sepsis. Thirty-one patients died, including 12 of 19 patients receiving steroids. Stepwise discriminant analysis revealed that the APACHE II score and steroid use were each independently associated with the rate of mortality. We report a prospective validation of pretreatment APACHE II scoring in abdominal sepsis. Steroid use is an independent risk factor. 相似文献
2.
R A Mustard J M Bohnen S Haseeb R Kasina 《Archives of surgery (Chicago, Ill. : 1960)》1987,122(1):69-73
We studied 108 patients undergoing clean-contaminated and dirty surgical procedures to determine whether daily C-reactive protein (CRP) measurements for 14 days postoperatively could predict the occurrence of septic complications prior to clinical diagnosis. Diagnostic criteria for septic complications and positive CRP response were defined in advance of the study. The CRP assays were carried out using an automated laser nephelometer system after the patient's discharge from the hospital. Forty-six septic complications were diagnosed in 40 patients. These complications consisted of wound infection (23), urinary tract infection (11), pneumonia (six), upper respiratory tract infection (three), intra-abdominal abscess (one), and other (two). The CRP testing was found to have a positive predictive value of 69% and a negative predictive value of 78%. We conclude that serial CRP measurements may be a valuable adjunct to surgical care in patients at high risk of postoperative septic complications. 相似文献
3.
Desferrioxamine (DFO) metabolism and its pharmacokinetics were studied in a swine model using high-performance liquid chromatography. DFO and three iron-binding metabolites occurred in plasma. Interindividual differences in pharmacokinetics and metabolism were observed. Urine analysis in 4 pigs showed three iron-binding metabolites. The mean percent dose excreted in urine in the form of the parent drug was 45 +/- 10% and 10 +/- 2% (means +/- SD) in the form of metabolites. Of the total amount of the parent drug infused, 3 h after initiation, 87% was in the form of DFO, whereas 13% was present as the DFO-iron III complex which represented 45 mg of urinary iron elimination. The described DFO infusion protocol provides for sufficient DFO to chelate significant amounts of ferric iron in excess of normal levels, thus allowing experimental studies of iron chelation in a variety of disease states. 相似文献
4.
目的 探讨创伤后迟发性脑肿胀的临床特点、发病机制与治疗。方法 回顾性分析1998年1月~2005年6月年收治的17例迟发性脑肿胀患者的临床特点和救治情况。结果 所有颅脑损伤患者采用保守治疗后均有好转,但于伤后5-10d出现恶化,CT复查有脑肿胀,经加强综合脱水等治疗后16例治愈,1例死亡。结论 迟发性脑肿胀好发于对冲性额、颞叶挫裂伤伴明显蛛网膜下腔出血、硬膜下薄层血肿及早期CT有脑肿胀者。其发病机制可能与创伤后的迟发性脑血管痉挛、微循环障碍、静脉回流障碍及甘露醇作用下降等因素有关。此类患者病情隐蔽性强,应加强观察、积极行CT复查,如能早期明确诊断,保守治疗多数效果良好。 相似文献
5.
The authors describe the management by percutaneous drainage of a rare solitary tuberculous liver abscess in a 37-year-old woman. Open surgical drainage of such abscesses can be avoided using percutaneous drainage combined with transcatheter infusions of antituberculous agents. For the safe and successful use of this method three criteria must be met: the abscess should be unilocular, there must be a safe access route and a previously sterile compartment must not be contaminated. In addition a small (22 or 23 gauge) needle should be used for the initial puncture. 相似文献
6.
Retrorenal colon: implications for percutaneous diskectomy 总被引:1,自引:0,他引:1
It has been recommended that computed tomography (CT) with the patient prone be performed in every patient undergoing percutaneous diskectomy; this would enable detection of a retrorenal location of the colon, which could interfere with the percutaneous procedure. In this evaluation of 346 prone CT studies, only one patient (0.29%) was found to have retrorenal or retropsoas bowel that would have been perforated at diskectomy. Because of this extremely low prevalence, the performance of prone CT in every patient undergoing percutaneous lumbar diskectomy is not believed to be necessary. 相似文献
7.
8.
9.
10.
郭永建 《福建医科大学学报》1994,(1)
采用间接ELISA检测23名肾移植受者血清巨细胞病毒(CMV)抗体,共检出18名(78%)活动性CMV感染,其中10名(44%)为原发性感染。结果证实CMV-IgE和-IgA具有较好的血清学诊断价值,优于CMV-IgM。 相似文献