全文获取类型
收费全文 | 27300篇 |
免费 | 1340篇 |
国内免费 | 69篇 |
专业分类
耳鼻咽喉 | 652篇 |
儿科学 | 1142篇 |
妇产科学 | 405篇 |
基础医学 | 2964篇 |
口腔科学 | 558篇 |
临床医学 | 1674篇 |
内科学 | 7272篇 |
皮肤病学 | 1073篇 |
神经病学 | 1863篇 |
特种医学 | 708篇 |
外科学 | 4209篇 |
综合类 | 114篇 |
一般理论 | 6篇 |
预防医学 | 2289篇 |
眼科学 | 745篇 |
药学 | 1567篇 |
中国医学 | 69篇 |
肿瘤学 | 1399篇 |
出版年
2023年 | 133篇 |
2022年 | 82篇 |
2021年 | 577篇 |
2020年 | 247篇 |
2019年 | 669篇 |
2018年 | 1052篇 |
2017年 | 621篇 |
2016年 | 526篇 |
2015年 | 586篇 |
2014年 | 603篇 |
2013年 | 978篇 |
2012年 | 1779篇 |
2011年 | 1948篇 |
2010年 | 1031篇 |
2009年 | 761篇 |
2008年 | 1602篇 |
2007年 | 1780篇 |
2006年 | 1628篇 |
2005年 | 1670篇 |
2004年 | 1498篇 |
2003年 | 1477篇 |
2002年 | 1432篇 |
2001年 | 1086篇 |
2000年 | 1356篇 |
1999年 | 991篇 |
1998年 | 138篇 |
1997年 | 92篇 |
1996年 | 105篇 |
1995年 | 70篇 |
1994年 | 46篇 |
1993年 | 52篇 |
1992年 | 330篇 |
1991年 | 246篇 |
1990年 | 201篇 |
1989年 | 152篇 |
1988年 | 154篇 |
1987年 | 155篇 |
1986年 | 120篇 |
1985年 | 111篇 |
1984年 | 84篇 |
1983年 | 61篇 |
1981年 | 32篇 |
1979年 | 55篇 |
1976年 | 31篇 |
1974年 | 31篇 |
1973年 | 34篇 |
1972年 | 30篇 |
1971年 | 27篇 |
1970年 | 25篇 |
1968年 | 28篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
2.
Jose M. Morales Jose Angel Martinez-Flores Manuel Serrano Maria José Castro Francisco Javier Alfaro Florencio García Miguel Angel Martínez Amado Andrés Esther González Manuel Praga Estela Paz-Artal Antonio Serrano 《Journal of the American Society of Nephrology : JASN》2015,26(3):735-745
In the current immunosuppressive therapy era, vessel thrombosis is the most common cause of early graft loss after renal transplantation. The prevalence of IgA anti–β2-glycoprotein I antibodies (IgA-aB2GPI-ab) in patients on dialysis is elevated (>30%), and these antibodies correlate with mortality and cardiovascular morbidity. To evaluate the effect of IgA-aB2GPI-ab in patients with transplants, we followed all patients transplanted from 2000 to 2002 in the Hospital 12 de Octubre prospectively for 10 years. Presence of IgA-aB2GPI-ab in pretransplant serum was examined retrospectively. Of 269 patients, 89 patients were positive for IgA-aB2GPI-ab (33%; group 1), and the remaining patients were negative (67%; group 2). Graft loss at 6 months post-transplant was significantly higher in group 1 (10 of 89 versus 3 of 180 patients in group 2; P=0.002). The most frequent cause of graft loss was thrombosis of the vessels, which was observed only in group 1 (8 of 10 versus 0 of 3 patients in group 2; P=0.04). Multivariate analysis showed that the presence of IgA-aB2GPI-ab was an independent risk factor for early graft loss (P=0.04) and delayed graft function (P=0.04). There were no significant differences regarding patient survival between the two groups. Graft survival was similar in both groups after 6 months. In conclusion, patients with pretransplant IgA-aB2GPI-ab have a high risk of early graft loss caused by thrombosis and a high risk of delayed graft function. Therefore, pretransplant IgA-aB2GPI-ab may have a detrimental effect on early clinical outcomes after renal transplantation. 相似文献
3.
4.
5.
6.
Maite Cruz Piqueras Ainhoa Rodríguez García de Cortazar Joaquín Hortal Carmona Javier Padilla Bernáldez 《Gaceta sanitaria / S.E.S.P.A.S》2019,33(1)
Objective
To analyse and understand vaccination hesitancy discourses, particularly those of people who have decided not to vaccinate their sons and daughters.Methods
Qualitative study of five individual interviews and two focus groups with people who chose not to vaccinate their children in the province of Granada (Spain).Results
Mothers and fathers manifest a system of health beliefs different to the biomedical paradigm. From an ethical point of view, they justify their position based on the right to autonomy and responsibility for their decisions. Alleged specific reasons: they doubt administration of several vaccines simultaneously at an early age in a systematic way and without individualising each case; they fear adverse effects and do not understand the variations of the vaccination schedule.Conclusions
These vaccination hesitancy discourses respond to the individual vs collective conflict; parents defend their right to bring up their children without any interference from the state and focus their responsibility on the individual welfare of their sons and daughters, regardless of the consequences that their actions might have on the collective. In their management of risks, they consider those derived from vaccination more relevant than the individual or collective consequences of not doing so. The vaccines generating most doubts are the more controversial ones within the scientific world. Transparency in communication of adverse effects; authorities respect for other health/disease concepts; banishment of the term “anti-vaccines” from the media and scientific vocabulary, and developing spaces for dialogue are bridges to be built. 相似文献7.
Rosario Fernández-Plata Rogelio Pérez-Padilla Rodrigo Del Río-Hidalgo Cecilia García-Sancho Laura Gochicoa-Rangel Christian Rodríguez-Hernández Luis Torre-Bouscoulet David Martínez-Briseño 《Archivos de bronconeumología》2019,55(10):513-518
IntroductionPeople with Down syndrome (DS) have high respiratory morbidity, evaluating their respiratory health with standardized, objective tests is desirable. Thus, the objective of this study was to evaluate the technical quality of Pulmonary Function Tests (PFTs) to determine which ones are most suitable for this population.MethodsParticipants included children, teenagers and adults with DS, 5 years of age or older (n = 302). The technical quality of the impulse oscillometry system (IOS), forced spirometry, lung-diffusing capacity for carbon monoxide (DLCO), and 6-min walk test (6MWT) were analyzed by age group. Capnography and pulse oximetry were included in the study. Technical quality was determined on the basis of current international PFTs standards.ResultsFifty-one percent of participants were males. A total of 184 participants (71%) who completed the IOS fulfilled the quality criteria, while 210 (70%) completed the 6MWT. Performance on forced spirometry and DLCO was poor. All pulse oximetries and 96% percent heart rates obtained had good quality, but exhaled carbon dioxide (PetCO2) and respiratory rate (RR) showed deficient repeatability.ConclusionsIOS appears to be the most reliable instrument for evaluating lung mechanics in individuals with DS. 相似文献
8.
María Cabrerizo Gloria Trallero María José Pena Amaia Cilla Gregoria Megias Carmen Mu?oz-Almagro Eva Del Amo Diana Roda Ana Isabel Mensalvas Antonio Moreno-Docón Juan García-Costa Nuria Rabella Manuel Ome?aca María Pilar Romero Sara Sanbonmatsu-Gámez Mercedes Pérez-Ruiz María José Santos-Mu?oz Cristina Calvo And the study group of “Enterovirus parechovirus infections in children under ?years-old Spain” PI- 《European journal of pediatrics》2015,174(11):1511-1516
9.
10.