全文获取类型
收费全文 | 4907篇 |
免费 | 260篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 45篇 |
儿科学 | 138篇 |
妇产科学 | 68篇 |
基础医学 | 549篇 |
口腔科学 | 150篇 |
临床医学 | 353篇 |
内科学 | 1123篇 |
皮肤病学 | 165篇 |
神经病学 | 454篇 |
特种医学 | 158篇 |
外科学 | 793篇 |
综合类 | 30篇 |
预防医学 | 141篇 |
眼科学 | 128篇 |
药学 | 489篇 |
中国医学 | 22篇 |
肿瘤学 | 380篇 |
出版年
2023年 | 37篇 |
2022年 | 58篇 |
2021年 | 98篇 |
2020年 | 55篇 |
2019年 | 85篇 |
2018年 | 116篇 |
2017年 | 84篇 |
2016年 | 102篇 |
2015年 | 103篇 |
2014年 | 142篇 |
2013年 | 178篇 |
2012年 | 263篇 |
2011年 | 308篇 |
2010年 | 167篇 |
2009年 | 142篇 |
2008年 | 229篇 |
2007年 | 274篇 |
2006年 | 274篇 |
2005年 | 253篇 |
2004年 | 238篇 |
2003年 | 250篇 |
2002年 | 219篇 |
2001年 | 139篇 |
2000年 | 154篇 |
1999年 | 167篇 |
1998年 | 62篇 |
1997年 | 50篇 |
1996年 | 55篇 |
1995年 | 28篇 |
1994年 | 31篇 |
1993年 | 35篇 |
1992年 | 96篇 |
1991年 | 76篇 |
1990年 | 76篇 |
1989年 | 85篇 |
1988年 | 45篇 |
1987年 | 41篇 |
1986年 | 46篇 |
1985年 | 43篇 |
1984年 | 20篇 |
1983年 | 26篇 |
1979年 | 24篇 |
1978年 | 23篇 |
1977年 | 15篇 |
1975年 | 13篇 |
1974年 | 17篇 |
1973年 | 14篇 |
1972年 | 15篇 |
1970年 | 14篇 |
1969年 | 19篇 |
排序方式: 共有5186条查询结果,搜索用时 15 毫秒
1.
Madoka Minoguchi Nobuyuki Yanagawa Chisato Ishikawa Junpei Sasajima Mitsuru Goto Miho Okamoto Yoshinori Saito Masanori Murakami Yutaka Orii Toru Yaosaka 《Nihon Shokakibyo Gakkai zasshi》2007,104(7):1082-1087
Pancreatic metastasis of malignant melanoma is rarely diagnosed while the patient is alive. We report a case of metastatic melanoma of the pancreas in a 35-year-old woman presenting with a solid mass of the pancreas. Her past medical history included a radical hysterectomy 2 years previously for malignant melanoma of the vagina. Twelve months later, lung metastasis was also resected. EUS-guided fine needle aspiration (EUS-FNA) identified that the pancreatic tumor was histologically and immunohistochemically identical to the surgical specimen of her lung neoplasm. Imaging studies including US, CT, and MRI have limited value to distinguish the tumors from primary ductal adenocarcinoma. EUS-FNA can provide tissue diagnosis from pancreatic masses, specifically when other modalities have failed. 相似文献
2.
Toshifumi Gabata Osamu Matsui Masumi Kadoya Samon Miyata Mitsuo Fujimura Tsutomu Takashima 《Cardiovascular and interventional radiology》1995,18(5):327-329
Gross hemorrhage is the most serious complication of anticoagulant therapy. We report the discovery and treatment of a large pseudoaneurysm of the superior gluteal artery in one patient who had been receiving oral anticoagulant therapy. We diagnosed the pseudoaneurysm by contrast-enhanced computed tomography, and embolized the artery with stainless steel coils. The exact cause of the pseudoaneurysm remains unclear, however, minor trauma appears most likely. 相似文献
3.
Hard metal asthma: cross immunological and respiratory reactivity between cobalt and nickel? 总被引:2,自引:1,他引:1 下载免费PDF全文
Eight asthmatic patients with hard metal asthma due to cobalt underwent bronchial provocation challenge with nickel sulphate. Seven patients developed a fall in FEV1 of 20% or more after inhaling nickel sulphate, four showing an immediate response and three a late response. Eight control subjects, including six asthmatic patients, with no history of hard metal exposure, showed no bronchoconstriction in response to a provocation challenge with nickel sulphate. Specific antibodies to nickel conjugated human serum albumin were present in four of the eight patients with sensitivity to cobalt conjugated human serum albumin but were absent from the serum of 60 unexposed asthmatic patients and 25 exposed symptom free workers. These results suggest that nickel as well as cobalt sensitivity plays a part in hard metal asthma. 相似文献
4.
5.
6.
7.
Yutaka Yonemura Masataka Segawa Hisashi Matsumoto Kouichirou Tsugawa Itasu Ninomiya Luis Fonseca Takashi Fujimura Kazuo Sugiyama Kouichi Miwa Itsuo Miyazaki 《Surgery today》1994,24(6):488-493
Because gastric cancers located in the upper third of the stomach are difficult to detect at an early stage, the surgical results remain poor. We performed R4 gastrectomy as a radical procedure for 25 patients, involving complete resection of the latero-aortic and interaorticovenous lymph modes above and below the left renal vein, in combination with the ordinary R2 or R3 gastrectomy (the R4 group). These patients were compared with 156 others who underwent R2 gastrectomy alone (the R2 group). There were no significant differences in operation time, blood loss, or the incidence of complications between the two groups; however, when the survival rates of the patients with tumors invading beyond the subserosa were compared, the 5-year survival rate was found to be significantly higher in the R4 group than in the R2 group. Furthermore, in patients with para-aortic nodal involvement, a significant survival advantage was observed in the R4 group, as compared with the R2 group. These results suggest that the R4 gastrectomy is a rational approach for patients with advanced gastric cancer located in the upper third of the stomach. 相似文献
8.
To examine whether prostacyclin has an attenuating effect on nonspecific bronchial responsiveness in asthma, we measured provocative concentration of methacholine producing a 20% fall in forced expiratory volume in 1 second (PC20-FEV1) before and after oral administration of a chemically stable prostacyclin analog (OP-41483) (200 μg 4 times a day for 4 days) in 8 patients with stable asthma. Neither baseline pulmonary function nor PC20-FEV1 significantly improved after the treatment. These results suggest that prostacyclin may have no direct effect on bronchial responsiveness in asthmatics. Further studies using more potent and long-lasting prostacyclin mimetic will be needed to confirm the conclusion. 相似文献
9.
10.
M. Fujimura Y. Nishizawa M. Nishitsuji M. Abo T. Kita S. Nomura 《Clinical and experimental allergy》2003,33(5):588-594
OBJECTIVE: Cough variant asthma and atopic cough are different clinical manifestations of eosinophilic airway inflammation presenting with isolated chronic non-productive cough. The aim of this study was to examine the longitudinal change in pulmonary function in cough variant asthma and atopic cough. METHODS: Longitudinal change in FEV1 was prospectively examined in 20 patients with cough variant asthma, 14 patients with atopic cough and 271 asymptomatic healthy subjects. All were lifetime non-smokers. Of the 20 cough variant asthma patients, 13 were taking long-term inhaled corticosteroid therapy (ICS) (beclomethasone dipropionate 615 +/- 58 micro g/day) and the other seven were not. Spirometry was taken at first visit, after cough was almost completely relieved on therapy, and at least once every year for 5 or more years afterwards. RESULTS: The slope of longitudinal change in FEV1 was not significantly different among cough variant asthma patients (- 0.029 +/- 0.007/year), atopic cough patients (- 0.021 +/- 0.022/year) and asymptomatic subjects (- 0.028 +/- 0.002 L/year). In patients with cough variant asthma, the slope in patients not taking inhaled corticosteroids (ICS) was 0.032 +/- 0.007 L/year, which was not significantly different from that in patients taking ICS (- 0.027 +/- 0.010 L/year). CONCLUSION: Pulmonary function decline is not greater in cough variant asthma than atopic cough and the normal population, and long-term ICS has no effect on the decline in cough variant asthma. 相似文献