收费全文 | 20142篇 |
免费 | 1849篇 |
国内免费 | 28篇 |
耳鼻咽喉 | 209篇 |
儿科学 | 655篇 |
妇产科学 | 447篇 |
基础医学 | 2618篇 |
口腔科学 | 502篇 |
临床医学 | 2440篇 |
内科学 | 3783篇 |
皮肤病学 | 316篇 |
神经病学 | 1866篇 |
特种医学 | 701篇 |
外科学 | 2791篇 |
综合类 | 385篇 |
一般理论 | 16篇 |
预防医学 | 2115篇 |
眼科学 | 377篇 |
药学 | 1311篇 |
中国医学 | 19篇 |
肿瘤学 | 1468篇 |
2021年 | 294篇 |
2020年 | 191篇 |
2019年 | 312篇 |
2018年 | 369篇 |
2017年 | 304篇 |
2016年 | 311篇 |
2015年 | 321篇 |
2014年 | 454篇 |
2013年 | 710篇 |
2012年 | 999篇 |
2011年 | 982篇 |
2010年 | 543篇 |
2009年 | 525篇 |
2008年 | 905篇 |
2007年 | 979篇 |
2006年 | 1029篇 |
2005年 | 938篇 |
2004年 | 898篇 |
2003年 | 778篇 |
2002年 | 789篇 |
2001年 | 627篇 |
2000年 | 627篇 |
1999年 | 560篇 |
1998年 | 235篇 |
1997年 | 217篇 |
1996年 | 180篇 |
1995年 | 192篇 |
1994年 | 170篇 |
1993年 | 159篇 |
1992年 | 381篇 |
1991年 | 398篇 |
1990年 | 438篇 |
1989年 | 380篇 |
1988年 | 329篇 |
1987年 | 310篇 |
1986年 | 332篇 |
1985年 | 293篇 |
1984年 | 254篇 |
1983年 | 207篇 |
1982年 | 155篇 |
1981年 | 136篇 |
1980年 | 140篇 |
1979年 | 209篇 |
1978年 | 167篇 |
1977年 | 146篇 |
1976年 | 173篇 |
1974年 | 159篇 |
1973年 | 159篇 |
1972年 | 161篇 |
1971年 | 138篇 |
Background
A history of childhood maltreatment and psychopathology are common in adults with obesity.Objectives
To report childhood maltreatment and to evaluate associations between severity and type of childhood maltreatment and lifetime history of psychopathology among adults with severe obesity awaiting bariatric surgery.Setting
Four clinical centers of the Longitudinal Assessment of Bariatric Surgery Research Consortium.Methods
The Childhood Trauma Questionnaire, which assesses presence/severity (i.e., none, mild, moderate, severe) of physical abuse, mental abuse, physical neglect, mental neglect, and sexual abuse, was completed by 302 female and 66 male bariatric surgery patients. Presurgery lifetime history of psychopathology and suicidal ideation/behavior were assessed with the Structured Clinical Interview for DSM-IV and the Suicidal Behavioral Questionnaire-Revised, respectively. Presurgery lifetime history of antidepressant use was self-reported.Results
Two thirds (66.6%) of females and 47.0% of males reported at least 1 form of childhood trauma; 42.4% and 24.2%, respectively, at greater than or equal to moderate severity. Among women, presence/greater severity of childhood mental or physical abuse or neglect was associated with a higher risk of history of psychopathology (i.e., major depressive disorder, posttraumatic stress disorder, other anxiety disorder, alcohol use disorder, binge eating disorder), suicidal ideation/behavior and antidepressant use (P for all ≤ .02). These associations were independent of age, race, education, body mass index, and childhood sexual abuse. Childhood sexual abuse was independently associated with a history of suicidal ideation/behavior and antidepressant use only (P for both ≤ .05). Statistical power was limited to evaluate these associations among men.Conclusion
Among women with obesity, presence/severity of childhood trauma was positively associated with relatively common psychiatric disorders. 相似文献Methods: 3,742 individuals with T1D age ≥50 were followed for dementia from 1/1/96-9/30/2015. Depression, dementia, and comorbidities were abstracted from electronic medical records. Cox proportional hazard models estimated the association between depression and dementia adjusting for demographics, glycosylated hemoglobin, severe dysglycemic epidsodes, stroke, heart disease, nephropathy, and end stage renal disease. The cumulative incidence of dementia by depression was estimated conditional on survival dementia-free to age 55.
Results: Five percent (N = 182) were diagnosed with dementia and 20% had baseline depression. Depression was associated with a 72% increase in dementia (fully adjusted HR = 1.72; 95% CI:1.12-2.65). The 25-year cumulative incidence of dementia was more than double for those with versus without depression (27% vs. 12%).
Conclusions: For people with T1D, depression significantly increases dementia risk. Given the pervasiveness of depression in T1D, this has major implications for successful aging in this population recently living to old age. 相似文献