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Case note data were obtained for 186 elderly primary care attenderswho also completed the 15 item Geriatric Depression Scale (GDS15).The presence or absence in the case notes of a current or pastdiagnosis of depression, of current treatment of depression,and of a number of clinical features of depression were noted.Case notes were also rated for the presence or absence of contraindicationsto the use of tricyclic antidepressants (TCAs) and to serotonin-specificreuptake inhibitors (SSRIs). Whereas 65 (35%) patients wererated as cases of depression on the GDS15, only28 (15%) had a current case note diagnosis of depression and37 (20%) had one or more current symptoms of depression recordedin the case notes. Patients rated by their GP as having oneor more current symptoms of depression scored higher on theGDS15 (P < 0.05) and were more likely to be categorized asa GDS case (P = 0.05). There was no significant relationshipbetween GDS caseness and a current case note diagnosis of depression.Seventy-three patients (39%) had a past history of depressionand 53 (28.5%) patients had previously been treated with antidepressants.The former was significantly associated with GDS caseness (P< 0.05). Twenty-four patients (13%) were currently on antidepressants,19 of them receiving adequate doses (equivalent to at least75 mg of amitriptyline). Current antidepressant treatment wasnot associated with GDS caseness. A significantlyhigher proportion of patients (both in the sample as a wholeand in the subgroup of GDS15 depression cases)had a medical condition or were taking a drug that mitigatedagainst the use of TCAs than was the case for SSRIs. 相似文献
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BETSY THOM CHERYL BROWN COLIN DRUMMOND GRIFFITH EDWARDS MICHAEL MULLAN COLIN TAYLOR 《Addiction (Abingdon, England)》1992,87(4):601-611
This paper considers the impact of the first consultation at a specialist alcohol clinic on patients' perceptions of their drink problem and on their expectations of help from three sources: an alcohol clinic, general practitioners and Alcoholics Anonymous. AT intake, mates had higher expectations than females of help from the alcohol clinic while people in manual occupations and those in the ‘less heavy’ drinking category had higher expectations of general practitioner help than other patients. Change was found to occur during the first clinic consultation so that by the end of the session patients had raised their rating of problem seventy and their expectations of help from the three sources examined. Overall, patient perceptions of the clinic assessment session were positive. The study highlights the importance of obtaining a full understanding of the process of engagement in treatment and indicates the potential of a clinical assessment to effect change in patient attitudes. 相似文献
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The method of planar imaging utilizing Bremsstrahlung radiation in patients treated with intraarticular Yttrium-90 for joint synovitis is described, illustrated and discussed. 相似文献
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MICHAEL MULLAN 《Addiction (Abingdon, England)》1989,84(12):1433-1440
Molecular biology is transforming our view of psychiatry. For the first time methods are becoming available to detect directly the genetic abnormalities leading to psychiatric illness. This article examines the ways in which the new marker technology might bridge the gap between classical genetic knowledge of alcoholism and the precise identification and localization of specific genes implicated in its aetiology. 相似文献
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