排序方式: 共有23条查询结果,搜索用时 15 毫秒
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Julio López‐Bastida PhD Lilisbeth Perestelo‐Pérez MPsych Fernando Montón‐álvarez PhD Pedro Serrano‐Aguilar PhD 《Movement disorders》2008,23(2):212-217
To determine the economic burden (direct and indirect costs), as well as health‐related quality of life (HRQOL) in patients diagnosed with spinocerebellar ataxia (SCA) in Spain. A cross‐sectional study was carried out on 84 patients with SCA from the Spanish Ataxia Federation (FEDAES) during 2004. A retrospective assessment of the use of resources was obtained through questionnaires filled out by the patients or the patient's caregivers. The approach used was the cost‐of‐illness study based on a societal perspective. To assess HRQOL in patients with SCA, they were asked to fill out the EQ‐5D generic questionnaire. The mean annual cost per patient with SCA was €18,776. The most important categories of costs were informal care, early retirement (permanent disability), medications, and orthopaedic devises. The mean EQ‐5D index score was 0.48 (0.38 for high and 0.58 for low severity patients) and the mean EQ‐5D VAS score was 48 (43 for high and 52 for low severity patients). Considerations of the costs related to caregivers due to the patients' disabilities, as well as the high indirect costs resulting from permanent disabilities in patients with SCA, should become a priority for health authorities. Furthermore, the patients' quality of life, as determined by the EQ‐5D questionnaire, was very low and substantially influenced by the degree of severity of SCA. © 2007 Movement Disorder Society 相似文献
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Lilisbeth Perestelo-Perez Jeanette Perez-Ramos Marien Gonzalez-Lorenzo Amado Rivero-Santana Pedro Serrano-Aguilar 《Patient education and counseling》2010
Objective
This study presents ongoing research aimed at understanding the suitability and impact of various decision aids (DAs) on patients with different chronic conditions in the Spanish National Health System.Methods
A three-phase process was employed to develop and evaluate DAs for patients with hip or knee osteoarthritis (OA), benign prostatic hyperplasia (BPH), and depression, including: (1) systematic reviews on the effectiveness of shared decision making (SDM) interventions (including DAs); (2) the development of DAs; (3) a pilot study assessing the DAs.Results
Systematic reviews carried out highlight that there are few studies assessing the effectiveness of DAs for OA, BPH, and depression. The development of DAs and their assessment currently differs for each medical condition. The DAs assessed for OA and BHP are well accepted. In a pilot study with OA patients, the DA produced a significant improvement in the decisional conflict “informed” subscale.Conclusion
Research on SDM and DAs for different chronic conditions is at a very early stage in Spain. It is not possible to draw any definite conclusions about the effectiveness of DAs for clinical practice.Practice implications
It is necessary to conduct more high quality studies to evaluate the effects of DAs in the Spanish context. 相似文献7.
Lilisbeth Perestelo‐Prez Amado Rivero‐Santana Ana Isabel Gonzlez‐Gonzlez Carlos Jesús Bermejo‐Caja Vanesa Ramos‐García Dbora Koatz Alezandra Torres‐Castao Marta Ballester Marcos Muoz‐Balsa Yolanda del Rey‐Granado Francisco Javier Prez‐Rivas Yolanda Canellas‐Criado Ana Beln Ramírez‐Puerta Valeria Pacheco‐Huergo Carola Orrego 《Health expectations》2021,24(1):33-41
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Amado Rivero-Santana Leticia Cuéllar-Pompa Luis M. Sánchez-Gómez Lilisbeth Perestelo-Pérez Pedro Serrano-Aguilar 《Health policy (Amsterdam, Netherlands)》2014
Introduction
In the last years there has been a significant increase in reported cases of pertussis in developed countries, in spite of high rates of childhood immunization. Health institutions have recommended different vaccination strategies to reduce child morbidity and mortality: vaccination of adolescents and adults, pregnant women, people in contact with the newborn (cocoon strategy) and health care workers. The aim of this paper is to review the scientific evidence supporting these recommendations.Methods
Systematic review on the effectiveness and cost-effectiveness of the above strategies for the reduction of morbidity and mortality from pertussis in infants under 12 months. The electronic databases Medline, PreMedline, Embase, CRD, Cochrane Central, and Trip Database were consulted from 1990 to October 2012. The evidence was assessed using the GRADE system.Results
There were eight studies on the efficacy or safety of the strategies analyzed, and 18 economic evaluations. Direct evidence on the efficacy of these strategies is scarce. Economic evaluations suggest that vaccination of adolescents and adults would be cost-effective, although there is major uncertainty over the parameters used.Conclusions
From the perspective of health technology assessment, there is insufficient evidence to recommend the vaccination strategies evaluated. 相似文献10.
Juan Oliva-Moreno Julio López-Bastida Pedro Serrano-Aguilar Lilisbeth Perestelo-Pérez 《The European journal of health economics》2010,11(4):405-412
The aims of this study were to estimate medical expenditures on human immunodeficiency virus (HIV) treatment and to identify significant associated variables. We performed a retrospective multi-centre study in the Canary Islands using a sample of 569 patients recruited at outpatient visits. The study examined demographic and clinical variables, health-related quality of life (HRQOL), and health care resources. Clinical data was obtained from medical records and patient interviews. Several empirical models for identifying the relationship between health care costs and independent variables were developed. The greatest expense came from pharmaceutical expenditure (82.1% of direct costs), while hospital costs only represented 4.6% of total expenditure. The data showed a statistically significant association between health care costs and the CD4 count of the previous year. HRQOL was also a significant variable. Therefore, CD4 cell count can be used to predict health care costs in patients. Policymakers could use this information to help guide their decisions in allocating limited health care resources to HIV treatments. 相似文献