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1.
Harrell Taylor Howell Elizabeth A. Balbierz Amy Guel Luz Pena Juan Janevic Teresa Gorbenko Ksenia 《Maternal and child health journal》2022,26(4):913-922
Maternal and Child Health Journal - The purpose of this study was to explore the postpartum experiences of publicly-insured women of color, and identify how postpartum care can be improved to... 相似文献
2.
Maria Nazarova Pavel Novikov Ekaterina Ivanina Ksenia Kozlova Larisa Dobrynina Vadim V. Nikulin 《Human brain mapping》2021,42(8):2508
The spatial accuracy of transcranial magnetic stimulation (TMS) may be as small as a few millimeters. Despite such great potential, navigated TMS (nTMS) mapping is still underused for the assessment of motor plasticity, particularly in clinical settings. Here, we investigate the within‐limb somatotopy gradient as well as absolute and relative reliability of three hand muscle cortical representations (MCRs) using a comprehensive grid‐based sulcus‐informed nTMS motor mapping. We enrolled 22 young healthy male volunteers. Two nTMS mapping sessions were separated by 5–10 days. Motor evoked potentials were obtained from abductor pollicis brevis (APB), abductor digiti minimi, and extensor digitorum communis. In addition to individual MRI‐based analysis, we studied normalized MNI MCRs. For the reliability assessment, we calculated intraclass correlation and the smallest detectable change. Our results revealed a somatotopy gradient reflected by APB MCR having the most lateral location. Reliability analysis showed that the commonly used metrics of MCRs, such as areas, volumes, centers of gravity (COGs), and hotspots had a high relative and low absolute reliability for all three muscles. For within‐limb TMS somatotopy, the most common metrics such as the shifts between MCR COGs and hotspots had poor relative reliability. However, overlaps between different muscle MCRs were highly reliable. We, thus, provide novel evidence that inter‐muscle MCR interaction can be reliably traced using MCR overlaps while shifts between the COGs and hotspots of different MCRs are not suitable for this purpose. Our results have implications for the interpretation of nTMS motor mapping results in healthy subjects and patients with neurological conditions. 相似文献
3.
Olesya G. Bernikova Ksenia A. Sedova Natalia V. Arteyeva Aleksey O. Ovechkin Sergey N. Kharin Dmitry N. Shmakov Jan E. Azarov 《Journal of electrocardiology》2018,51(3):542-548
Background
Aim of the study was to find out which myocardial repolarization parameters predict reperfusion ventricular tachycardia and fibrillation (VT/VF) and determine how these parameters express in ECG.Methods
Coronary occlusion and reperfusion (30/30 min) was induced in 24 cats. Local activation and end of repolarization times (RT) were measured in 88 intramyocardial leads. Computer simulations of precordial electrograms were performed.Results
Reperfusion VT/VF developed in 10 animals. Arrhythmia-susceptible animals had longer RTs in perfused areas [183(177;202) vs 154(140;170) ms in susceptible and resistant animals, respectively, P < 0.05]. In logistic regression analysis, VT/VFs were associated with prolonged RTs in the perfused area (OR 1.068; 95% CI 1.012–1.128; P = 0.017). Simulations demonstrated that prolonged repolarization in the perfused/border zone caused precordial terminal T-wave inversion.Conclusions
The reperfusion VT/VFs were independently predicted by the longer RT in the perfused zone, which was reflected in the terminal negative phase of the electrocardiographic T-wave. 相似文献4.
5.
6.
This article focuses on the issues related to the machining of DMLS (Direct Metal Laser Sintering) laser sintered parts made of Inconel 718 alloy. Longitudinal turning with CBN (cubic boron nitride) tool inserts is analyzed. The authors made an attempt to establish a procedure to find the optimal finishing cutting parameters while minimizing the specific cutting force and taking into account the machined surface quality criterion. During experiments the influence of cutting data on the values of cutting force and specific cutting force were performed. Moreover, the results of measurements of surface roughness parameters and the results of analysis of chip form are presented as well. Cast Inconel 718 has also been tested for comparative purposes. The variability of the material’s hardening state during machining was found, as well as the variability of the specific cutting force value as a function of the cross-sectional shape of the cutting layer. The values of all components of the total cutting force for turning the material obtained by the additive method are lower than for turning the cast material by approximately 32%. At the end of the article, the authors present an application of the proposed optimization algorithm. It was established that by changing the cross-section shape of the cutting layer, it was possible to perform the turning process at a specific cutting force value of 22% less, which is achieved by reducing the cross-section size. 相似文献
7.
Retiform perineurioma is a rare distinct histologic subtype of benign soft tissue perineurioma. We report 1 case of retiform perineurioma with a superficial invasion of the adjacent skeletal muscle. The patient was a 34-year-old woman with a neoplasm located between the deltoid muscle and the biceps. Histologically, the tumor was nonencapsulated, composed exclusively of perineurial cells without cytologic and tissue atypia. There were focal areas in which the neoplastic cells infiltrated the muscle tissue, widely separating the bundles. This case may represent a diagnostic pitfall as it can be confused with a malignant perineurioma. 相似文献
8.
I. A. Gamaley Ksenia M. Kirpichnikova Irene V. Artzybasheva Igor V. Klyubin 《Pflügers Archiv : European journal of physiology》1999,438(1):113-115
The changes in membrane potential of L-929 fibroblasts caused by H2O2 (10–50 μM) at different phases of the cell cycle were investigated. The membrane potential of cells in G0, early G1, and
G2/M responded to H2O2 by hyperpolarizing, while cells in late G1/S responded by depolarizing. Quinidine (50 μM), a blocker of Ca2+-dependent K+ conductance, inhibited the hyperpolarization response of L-929 cells to H2O2 in all cases. Measurements of reactive oxygen species (ROS) production by the cells at the same cell cycle phases indicated
that the hyperpolarization response of the cells is linked with minimal production of ROS, and that the depolarization response
is associated with maximal production of ROS inside the cell.
Received: 5 February 1999 / Received after revision and accepted: 3 March 1999 相似文献
9.
Magnetic cell sorting for enriching Schwann cells from adult mouse peripheral nerves 总被引:6,自引:0,他引:6
Manent J Oguievetskaia K Bayer J Ratner N Giovannini M 《Journal of neuroscience methods》2003,123(2):167-173
We have devised a simple method to purify mitotically active Schwann cells (SC) from peripheral nerves of adult mice. Nerves were predegenerated in vitro for 7 days and after dissociation cells were plated on poly-L-lysine/laminin coated dishes in N2 serum-free culture medium supplemented with forskolin and heregulin-beta1. Primary cultures were purified from contaminating fibroblasts by magnetic cell sorting (MACS) based on SC membrane specific expression of p75(NGFR) and enriched to about 99% of SC after MACS from 34 to 91% before sorting. After sorting, purified adult mouse SC were propagated for three passages until confluent to a total surface of 160 cm(2) per mouse (two sciatic and two trigeminal nerves). In addition, we show that this method can be used to purify tumoral SC from mouse NF2-related schwannomas. 相似文献
10.
Mark Abie Horowitz Jasmin Wertz Danhui Zhu Annamaria Cattaneo Ksenia Musaelyan Naghmeh Nikkheslat Sandrine Thuret Carmine Maria Pariante Patricia Ana Zunszain 《The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP)》2015,18(3)