全文获取类型
收费全文 | 11873篇 |
免费 | 901篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 97篇 |
儿科学 | 420篇 |
妇产科学 | 260篇 |
基础医学 | 1388篇 |
口腔科学 | 136篇 |
临床医学 | 2200篇 |
内科学 | 1989篇 |
皮肤病学 | 193篇 |
神经病学 | 831篇 |
特种医学 | 607篇 |
外科学 | 1234篇 |
综合类 | 204篇 |
一般理论 | 12篇 |
预防医学 | 1418篇 |
眼科学 | 126篇 |
药学 | 717篇 |
中国医学 | 1篇 |
肿瘤学 | 956篇 |
出版年
2023年 | 52篇 |
2022年 | 91篇 |
2021年 | 194篇 |
2020年 | 133篇 |
2019年 | 168篇 |
2018年 | 237篇 |
2017年 | 156篇 |
2016年 | 199篇 |
2015年 | 208篇 |
2014年 | 361篇 |
2013年 | 480篇 |
2012年 | 713篇 |
2011年 | 846篇 |
2010年 | 424篇 |
2009年 | 389篇 |
2008年 | 733篇 |
2007年 | 807篇 |
2006年 | 729篇 |
2005年 | 786篇 |
2004年 | 687篇 |
2003年 | 612篇 |
2002年 | 636篇 |
2001年 | 185篇 |
2000年 | 192篇 |
1999年 | 210篇 |
1998年 | 112篇 |
1997年 | 97篇 |
1996年 | 101篇 |
1995年 | 116篇 |
1994年 | 110篇 |
1993年 | 90篇 |
1992年 | 158篇 |
1991年 | 145篇 |
1990年 | 135篇 |
1989年 | 121篇 |
1988年 | 117篇 |
1987年 | 123篇 |
1986年 | 113篇 |
1985年 | 130篇 |
1984年 | 114篇 |
1983年 | 92篇 |
1982年 | 69篇 |
1981年 | 39篇 |
1980年 | 53篇 |
1979年 | 52篇 |
1978年 | 45篇 |
1977年 | 31篇 |
1976年 | 43篇 |
1975年 | 33篇 |
1974年 | 37篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
3.
David M. Presby Michael C. Rudolph Vanessa D. Sherk Matthew R. Jackman Rebecca M. Foright Kenneth L. Jones Julie A. Houck Ginger C. Johnson Janine A. Higgins P. Darrell Neufer Robert H. Eckel Paul S. MacLean 《Diabetes》2021,70(4):867
Moderate weight loss improves numerous risk factors for cardiometabolic disease; however, long-term weight loss maintenance (WLM) is often thwarted by metabolic adaptations that suppress energy expenditure and facilitate weight regain. Skeletal muscle has a prominent role in energy homeostasis; therefore, we investigated the effect of WLM and weight regain on skeletal muscle in rodents. In skeletal muscle of obesity-prone rats, WLM reduced fat oxidative capacity and downregulated genes involved in fat metabolism. Interestingly, even after weight was regained, genes involved in fat metabolism were also reduced. We then subjected mice with skeletal muscle lipoprotein lipase overexpression (mCK-hLPL), which augments fat metabolism, to WLM and weight regain and found that mCK-hLPL attenuates weight regain by potentiating energy expenditure. Irrespective of genotype, weight regain suppressed dietary fat oxidation and downregulated genes involved in fat metabolism in skeletal muscle. However, mCK-hLPL mice oxidized more fat throughout weight regain and had greater expression of genes involved in fat metabolism and lower expression of genes involved in carbohydrate metabolism during WLM and regain. In summary, these results suggest that skeletal muscle fat oxidation is reduced during WLM and regain, and therapies that improve skeletal muscle fat metabolism may attenuate rapid weight regain. 相似文献
4.
Cheryl Wallerstedt RNC MS Patricia Higgins RN PhD 《Journal of obstetric, gynecologic, and neonatal nursing : JOGNN / NAACOG》1996,25(5):389-400
Society often expects mothers and fathers to share equally in the perinatal grief process because the child was a common bond between them. Unfortunately, in perinatal grief, this is not always the case. The mother and the father can experience incongruent grieving and use discordant coping mechanisms. It is important to evaluate these differences to facilitate communication between the distraught parents. Improved communication can in turn facilitate the grieving process. 相似文献
5.
6.
7.
Kai-Hang Yiu MBBS Chung-Wah Siu MBBS Chu-Pak Lau MD Kathy L.F. Lee MBBS Hung-Fat Tse MD 《Heart rhythm》2007,4(2):221-223
We report a case of successful transvenous, catheter-based, cavotricuspid isthmus ablation for treatment of atrial flutter using microwave energy. Microwave energy was delivered at 900–930 MHz using 21 W of power. Bidirectional cavotricuspid isthmus conduction block was achieved by microwave ablation without any patient discomfort or complication during the procedure. Our initial experience suggests that transcatheter microwave ablation is feasible for the cure of typical atrial flutter. 相似文献
8.
Marcus P Kennedy Raymond D Coakley Scott H Donaldson Robert M Aris Kathy Hohneker Joel P Wedd Michael R Knowles Peter H Gilligan James R Yankaskas 《Journal of cystic fibrosis》2007,6(4):267-273
BACKGROUND: The impact of infection with Burkholderia gladioli in cystic fibrosis, other chronic airway diseases and immunosuppressed patients is unknown. METHODS: A six-year retrospective review of all patients with B. gladioli infection was performed in a tertiary referral center with cystic fibrosis and lung transplantation programs. In addition, a targeted survey of all 251 lung transplant recipients was performed. Available B. gladioli isolates were analyzed via pulsed field gel electrophoresis. RESULTS: Thirty-five patients were culture positive for B. gladioli, including 33 CF patients. No bacteremia was identified. Isolates were available in 18 patients and all were genetically distinct. Two-thirds of these isolates were susceptible to usual anti-pseudomonal antibiotics. After acquisition, only 40% of CF patients were chronically infected (> or =2 positive cultures separated by at least 6 months). Chronic infection was associated with resistance to > or =2 antibiotic groups on initial culture and failure of eradication after antibiotic therapy. The impact of acquisition of B. gladioli infection in chronic infection was variable. Three CF patients with chronic infection underwent lung transplantation. One post-transplant patient developed a B. gladioli mediastinal abscess, which was treated successfully. CONCLUSIONS: The majority of patients' culture positive for B. gladioli at our center have CF. B. gladioli infection is often transient and is compatible with satisfactory post-lung transplantation outcomes. 相似文献
9.
10.