全文获取类型
收费全文 | 25827篇 |
免费 | 6786篇 |
国内免费 | 97篇 |
专业分类
耳鼻咽喉 | 379篇 |
儿科学 | 747篇 |
妇产科学 | 702篇 |
基础医学 | 1500篇 |
口腔科学 | 1432篇 |
临床医学 | 7338篇 |
内科学 | 5445篇 |
皮肤病学 | 651篇 |
神经病学 | 3281篇 |
特种医学 | 684篇 |
外科学 | 3098篇 |
综合类 | 117篇 |
现状与发展 | 2篇 |
一般理论 | 15篇 |
预防医学 | 4167篇 |
眼科学 | 414篇 |
药学 | 893篇 |
中国医学 | 4篇 |
肿瘤学 | 1841篇 |
出版年
2024年 | 240篇 |
2023年 | 1424篇 |
2022年 | 468篇 |
2021年 | 961篇 |
2020年 | 1350篇 |
2019年 | 816篇 |
2018年 | 1821篇 |
2017年 | 1925篇 |
2016年 | 1935篇 |
2015年 | 1927篇 |
2014年 | 2270篇 |
2013年 | 2377篇 |
2012年 | 1426篇 |
2011年 | 1473篇 |
2010年 | 1487篇 |
2009年 | 1758篇 |
2008年 | 1084篇 |
2007年 | 924篇 |
2006年 | 960篇 |
2005年 | 700篇 |
2004年 | 638篇 |
2003年 | 576篇 |
2002年 | 511篇 |
2001年 | 367篇 |
2000年 | 192篇 |
1999年 | 301篇 |
1998年 | 343篇 |
1997年 | 338篇 |
1996年 | 343篇 |
1995年 | 287篇 |
1994年 | 196篇 |
1993年 | 184篇 |
1992年 | 147篇 |
1991年 | 118篇 |
1990年 | 103篇 |
1989年 | 116篇 |
1988年 | 94篇 |
1987年 | 70篇 |
1986年 | 64篇 |
1985年 | 67篇 |
1984年 | 52篇 |
1983年 | 35篇 |
1982年 | 32篇 |
1981年 | 25篇 |
1980年 | 21篇 |
1979年 | 13篇 |
1978年 | 22篇 |
1977年 | 17篇 |
1975年 | 15篇 |
1974年 | 12篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Joseph M. Northey Kate L. Pumpa Clare Quinlan Ashley Ikin Kellie Toohey Disa J. Smee Ben Rattray 《Journal of Science and Medicine in Sport》2019,22(5):580-585
Objectives
The current study investigated the effects of two exercise interventions on cognitive function amongst breast cancer survivors.Design
Pilot randomised-controlled trial.Methods
Seventeen female cancer survivors (mean: 62.9 ± 7.8 years) were randomised into three groups: high-intensity interval training (HIIT, n = 6); moderate-intensity continuous training (MOD, n = 5); or wait-list control (CON, n = 6). The HIIT and MOD groups exercised on a cycle ergometer 3 days/week for 12-weeks. Primary outcomes were cognitive function assessments utilising CogState. Secondary outcomes were resting middle cerebral artery blood flow velocity, cerebrovascular reactivity and aerobic fitness (VO2peak). Data were analysed with General Linear Mixed Models and Cohen’s d effect sizes were calculated.Results
All 17 participants who were randomised were available for follow-up analysis and adherence was similar for HIIT and MOD (78.7 ± 13.2% vs 79.4 ± 12.0%; p = 0.93). Although there were no significant differences in the cognitive and cerebrovascular outcomes, HIIT produced moderate to large positive effects in comparison to MOD and CON for outcomes including episodic memory, working memory, executive function, cerebral blood flow and cerebrovascular reactivity. HIIT significantly increased VO2peak by 19.3% (d = 1.28) and MOD had a non-significant 5.6% (d = 0.72) increase, compared to CON which had a 2.6% decrease.Conclusions
This study provides preliminary evidence that HIIT may be an effective exercise intervention to improve cognitive performance, cerebrovascular function and aerobic fitness in breast cancer survivors. Considering the sample size is small, these results should be confirmed through larger clinical trials. 相似文献2.
3.
4.
5.
6.
7.
The purpose of this study was to investigate radiographic measurements in a cohort of patients with juvenile hallux valgus (with a hallux valgus angle > 15 degrees ) using standardized weightbearing x-rays compared with an age-matched control group. First metatarsal protrusion distance, metatarsus primus adductus angle, metatarsus adductus, first metatarsal cuneiform angle, calcaneal inclination angle, and talocalcaneal angles were assessed with discriminant functional analysis. A total of 37 sets of data were analyzed from patients with a mean age of 13.45 +/- 1.75 years. The study identified 2 significant components of juvenile hallux valgus: a positive first metatarsal protrusion distance (P <.001) and metatarsal primus adductus angle (P = .002). Discriminant functional analysis was then used to determine the best predictors of juvenile hallux valgus. This analysis allowed only 1 variable, metatarsal protrusion distance, as a predictor of whether juvenile hallux valgus was present (P < .001), with 94.3% accuracy. This study showed that a positive metatarsal protrusion distance is a significant component of juvenile hallux valgus. 相似文献
8.
C. O. Onyeaso BDS FWACS M. O. Arowojolu BDS FWACS J. O. Taiwo BDS MSc DDPH RCS Eng 《American journal of orthodontics and dentofacial orthopedics》2003,124(6):714-720
This prospective clinic-based study evaluated the pretreatment periodontal status of the orthodontic patients seen at the University College Hospital, Ibadan, Nigeria, and assessed the relationship between dental aesthetic index (DAI) scores and periodontal status according to community periodontal index of treatment needs (CPITN) scores. One hundred forty five patients-70 (48.3%) males and 75 (51.7%) females from 6 to 45 years (mean 15.8 +/- 7.5)-were seen. World Health Organization (WHO) guidelines were followed in the examination and reporting of the periodontal status, and DAI scores were assessed based on WHO guidelines. The chi-square test was used to determine the association between the DAI and the CPITN scores. Most patients were in the 6-15 (55.9%) or 16-25 (35.9%) age groups. Based on the WHO preferred cumulative calculations of treatment need (TN), 35.2% of the patients had TN 0, 64.9% had TN 1, 24.9% had TN 2, and only 0.7% had TN 3. The relationship between DAI scores and periodontal treatment needs was not statistically significant (P >.05). Although many patients were yet to attain the WHO goal of no more than 1 sextant affected by bleeding or calculus at the age of 15, over one third had satisfactory periodontal health. 相似文献
9.
10.
Angiotensin Converting Enzyme Inhibitors: Animal Experiments Suggest a New Pharmacological Treatment for Alcohol Abuse in Humans 总被引:1,自引:0,他引:1
G. Spinosa MSc E. Perlanski Dipl Tech. F. H. H. Leenen MD R. B. Stewart MSc L. A. Grupp DSc 《Alcoholism, clinical and experimental research》1988,12(1):65-70
The prevalence of heavy alcohol consumption is a major problem of increasing proportions throughout the world. Although alcohol sensitizing drugs and more recently serotonin uptake inhibitors are drug interventions with some following, their long term beneficial consequences have yet to be demonstrated. In recent years, we have demonstrated that manipulating activity in the renin-angiotensin system will dramatically alter voluntary alcohol consumption in rats. Based on these findings, the present study evaluated the ability of a class of drugs known as the angiotensin converting enzyme inhibitors to reduce voluntary alcohol drinking in laboratory animals. These drugs prevent the conversion of angiotensin I to angiotensin II. They have been licensed for use in Europe and North America and are indicated in the treatment of hypertension. Our experiments showed that both captopril (Capoten, Squibb) and enalapril (Vasotec, Merck Sharpe & Dohme) can reduce alcohol drinking in both normotensive and hypertensive animals regardless of whether the pattern of intake is in a bout or of a less exaggerated nature. Furthermore, this change in alcohol intake can occur without concomitant changes in blood pressure, plasma renin activity, overall fluid balance, or the distribution and metabolism of alcohol. Taken together these findings suggest that the angiotensin converting enzyme inhibitors should be evaluated in a clinical setting for they may prove to be a useful new treatment or treatment adjunct for alcohol abuse in humans. 相似文献