全文获取类型
收费全文 | 759篇 |
免费 | 60篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 4篇 |
妇产科学 | 16篇 |
基础医学 | 78篇 |
口腔科学 | 17篇 |
临床医学 | 185篇 |
内科学 | 111篇 |
皮肤病学 | 18篇 |
神经病学 | 104篇 |
特种医学 | 10篇 |
外科学 | 56篇 |
综合类 | 2篇 |
一般理论 | 1篇 |
预防医学 | 92篇 |
眼科学 | 5篇 |
药学 | 81篇 |
中国医学 | 3篇 |
肿瘤学 | 39篇 |
出版年
2023年 | 6篇 |
2022年 | 4篇 |
2021年 | 12篇 |
2020年 | 17篇 |
2019年 | 20篇 |
2018年 | 27篇 |
2017年 | 19篇 |
2016年 | 28篇 |
2015年 | 21篇 |
2014年 | 33篇 |
2013年 | 45篇 |
2012年 | 62篇 |
2011年 | 49篇 |
2010年 | 28篇 |
2009年 | 21篇 |
2008年 | 50篇 |
2007年 | 45篇 |
2006年 | 47篇 |
2005年 | 47篇 |
2004年 | 31篇 |
2003年 | 36篇 |
2002年 | 22篇 |
2001年 | 9篇 |
2000年 | 8篇 |
1999年 | 14篇 |
1998年 | 8篇 |
1997年 | 6篇 |
1996年 | 4篇 |
1995年 | 2篇 |
1994年 | 5篇 |
1993年 | 2篇 |
1992年 | 9篇 |
1991年 | 6篇 |
1990年 | 4篇 |
1989年 | 7篇 |
1988年 | 9篇 |
1987年 | 9篇 |
1986年 | 5篇 |
1985年 | 12篇 |
1984年 | 7篇 |
1983年 | 1篇 |
1982年 | 4篇 |
1981年 | 7篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1978年 | 6篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1974年 | 1篇 |
1972年 | 1篇 |
排序方式: 共有823条查询结果,搜索用时 15 毫秒
1.
The Framingham Disability Study: physical disability among community-dwelling survivors of stroke 总被引:6,自引:0,他引:6
A M Jette J L Pinsky L G Branch P A Wolf M Feinleib 《Journal of clinical epidemiology》1988,41(8):719-726
The relationship between stroke and physical disability was examined in a cohort of adult, Framingham, Massachusetts, residents who, between 1948 and 1951, were assembled for a longitudinal examination of cardiovascular disease. Multivariate analyses examined the amount of residual disability attributable to stroke among 2540 community-dwelling survivors, 27 years after their initial examination, after controlling for age, cardiovascular risk factors, other cardiovascular diseases, and eight general health conditions related to physical disability. Among men living in the community, a history of stroke explained 12% of the variance in physical disability. Suffering a stroke, however, was not as strongly related to physical disability among women living in the community, accounting for only 3% of the variance. Results suggest that although older men and women die from the same major causes, they may not be disabled by the same conditions. 相似文献
2.
3.
4.
Ursula R. Kees Jette Ford Pamela R. Ranford Susanne E. Peroni Jaclyn A. Biegel Annette H. Parmiter Lavinia A. Hallam Michael L. N. Willoughby Dominic Spagnolo 《Genes, chromosomes & cancer》1994,9(2):129-135
We have established two cell lines, PER-452 and PER-453, from an 8-month-old girl with an extensive pineoblastoma. Characterization of these lines revealed that the proto-oncogenes MYC and MYCN were not amplified, but both cell lines showed MYCN expression comparable to a cell line with 200-fold MYCN amplification. Both cell lines contained an i( 17q). These results support the concept that pineoblastomas belong to a larger group of primitive neuroectodermal tumors of the central nervous system. These two cell lines provide a unique opportunity to investigate the molecular genetic mechanisms underlying these neoplasms further. Genes Chrom Cancer 9:129-135 (1994).© 1994 Wiley-Liss, Inc. 相似文献
5.
6.
Madsen Christina Merete Tvede Bisgaard Sara Kjær Primdahl Jette Christensen Jeanette Reffstrup von Bülow Cecilie 《Journal of occupational rehabilitation》2021,31(4):866-885
Journal of Occupational Rehabilitation - Purpose To present an overview of the evidence of the effect of job loss prevention interventions, aiming to improve work ability and decrease absenteeism... 相似文献
7.
8.
Human papillomavirus mRNA and DNA testing in women with atypical squamous cells of undetermined significance: A prospective cohort study 下载免费PDF全文
Louise T. Thomsen Christian Dehlendorff Jette Junge Marianne Waldstrøm Doris Schledermann Kirsten Frederiksen Susanne K. Kjaer 《International journal of cancer. Journal international du cancer》2016,139(8):1839-1850
In this prospective cohort study, we compared the performance of human papillomavirus (HPV) mRNA and DNA testing of women with atypical squamous cells of undetermined significance (ASC‐US) during cervical cancer screening. Using a nationwide Danish pathology register, we identified women aged 30–65 years with ASC‐US during 2005–2011 who were tested for HPV16/18/31/33/45 mRNA using PreTect HPV‐Proofer (n = 3,226) or for high‐risk HPV (hrHPV) DNA using Hybrid Capture 2 (HC2) (n = 9,405) or Linear Array HPV‐Genotyping test (LA) (n = 1,533). Women with ≥1 subsequent examination in the register (n = 13,729) were followed for up to 9.5 years for high‐grade cervical intraepithelial neoplasia (CIN) or cancer. After 3 years' follow‐up, mRNA testing had higher specificity for CIN3 or worse (CIN3+) than HC2 testing (88.1% [95% confidence interval (CI): 86.8–89.6%] versus 59.3% [95% CI: 58.1–60.4%]) and higher positive predictive value (PPV) (38.2% [95% CI: 33.8%–43.1%] versus 19.5% [95% CI: 17.8–20.9%]). However, the sensitivity of mRNA testing was lower than that of HC2 testing (66.7% [95% CI: 59.3–74.5%] versus 97.0% [95% CI: 95.5–98.4%]), and women testing mRNA negative had higher 3‐year risk for CIN3+ than those testing HC2 negative (3.2% [95% CI: 2.2–4.2%] versus 0.5% [95% CI: 0.3–0.7%]). Patterns were similar after 18 months and 5 years'; follow‐up; for CIN2+ and cancer as outcomes; across all age groups; and when comparing mRNA testing to hrHPV DNA testing using LA. In conclusion, the HPV16/18/31/33/45 mRNA test is not optimal for ASC‐US triage due to its low sensitivity and the substantial risk for precancer following a negative test. 相似文献
9.
Lykkeberg AK Sengeløv G Cornett C Tjørnelund J Hansen SH Halling-Sørensen B 《Journal of pharmaceutical and biomedical analysis》2004,34(3):559-567
2-Acetyl-2-decarboxamido-oxytetracycline (ADOTC) is a major impurity of oxytetracycline (OTC) produced as a side product during fermentation. ADOTC was isolated from OTC and other impurities using preparative HPLC. The preparative column was an Xterra MS, C18 chromatographic column (100 mm x 19 mm i.d., 5 microm), and the mobile phase contained methanol-water (27:73 (v/v)) with 0.08 M formic acid added. The flow rate was 9.0 ml/min. It was possible to isolate few milligram ADOTC in a day. The compound was unambiguously identified using NMR and MS-MS. The anti-microbial activity against activated sludge bacteria was determined giving a potency of only 3% of that of OTC. With tetracycline-resistant bacteria, no anti-microbial activity was observed, indicating a mode of action similar to that of OTC. 相似文献
10.
Construction of meaningful identities in the context of rheumatoid arthritis,motherhood and paid work: A meta‐ethnography 下载免费PDF全文