全文获取类型
收费全文 | 17030篇 |
免费 | 1246篇 |
国内免费 | 89篇 |
专业分类
耳鼻咽喉 | 130篇 |
儿科学 | 522篇 |
妇产科学 | 317篇 |
基础医学 | 2766篇 |
口腔科学 | 377篇 |
临床医学 | 1607篇 |
内科学 | 3874篇 |
皮肤病学 | 384篇 |
神经病学 | 2017篇 |
特种医学 | 383篇 |
外科学 | 1673篇 |
综合类 | 75篇 |
一般理论 | 12篇 |
预防医学 | 1313篇 |
眼科学 | 193篇 |
药学 | 1265篇 |
中国医学 | 57篇 |
肿瘤学 | 1400篇 |
出版年
2024年 | 25篇 |
2023年 | 173篇 |
2022年 | 388篇 |
2021年 | 751篇 |
2020年 | 421篇 |
2019年 | 534篇 |
2018年 | 595篇 |
2017年 | 461篇 |
2016年 | 549篇 |
2015年 | 580篇 |
2014年 | 696篇 |
2013年 | 885篇 |
2012年 | 1343篇 |
2011年 | 1418篇 |
2010年 | 797篇 |
2009年 | 639篇 |
2008年 | 1040篇 |
2007年 | 1100篇 |
2006年 | 966篇 |
2005年 | 938篇 |
2004年 | 876篇 |
2003年 | 731篇 |
2002年 | 706篇 |
2001年 | 151篇 |
2000年 | 117篇 |
1999年 | 140篇 |
1998年 | 147篇 |
1997年 | 132篇 |
1996年 | 84篇 |
1995年 | 86篇 |
1994年 | 73篇 |
1993年 | 46篇 |
1992年 | 77篇 |
1991年 | 61篇 |
1990年 | 59篇 |
1989年 | 39篇 |
1988年 | 47篇 |
1987年 | 28篇 |
1986年 | 39篇 |
1985年 | 38篇 |
1984年 | 32篇 |
1983年 | 33篇 |
1982年 | 27篇 |
1981年 | 23篇 |
1979年 | 24篇 |
1978年 | 20篇 |
1977年 | 14篇 |
1974年 | 12篇 |
1973年 | 14篇 |
1966年 | 12篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Ariel Paracampo Marina Solis Carlos Bonetto 《International journal of environmental health research》2015,25(1):96-103
Chlorpyrifos is the most used insecticide in Argentina. Cnesterodon decemmaculatus is a widely distributed, endemic fish from Neotropical America. It attains high densities in the shallow water assemblages of Argentina and Brazil. The aim of this study was to assess the acute toxicity of chlorpyrifos to C. decemmaculatus. The mean 96-h LC50 of three independent determinations was 105.3 (±?3.1) μg/L. Sublethal effects were observed. Swimming behavioral changes at each chlorpyrifos exposure concentration were reported. C. decemmaculatus represents a good model for ecotoxicological risk assessment. 相似文献
2.
3.
4.
Sergue? O Fetissov Jarmila Hallman Ida Nilsson Ann-Kari Lefvert Lars Oreland Tomas H?kfelt 《Neuropsychopharmacology》2006,60(8):799-802
BACKGROUND: Altered stress response is characteristic for subjects with abnormal aggressive and antisocial behavior, but the underlying biological mechanisms are unclear. We hypothesized that autoantibodies (autoAbs) directed against several stress-related neurohormones may exist in aggressive subjects. METHODS: Using enzyme-linked immunosorbent assay, we studied whether autoAbs directed against corticotropin (ACTH), alpha-melanocyte-stimulating hormone (alpha-MSH), oxytocin, and vasopressin are present in serum of male subjects with conduct disorder and prisoners with history of violence. Healthy blood donors served as control subjects. RESULTS: Both conduct disorder and prisoners groups displayed strongly increased levels of ACTH-reactive immunoglobulin G (IgG) and immunoglobulin M (IgM) autoAbs compared with control subjects. Levels of oxytocin-reactive IgM autoAbs were slightly increased in both groups of aggressive subjects, whereas levels of vasopressin-reactive IgG and IgM autoAbs were lower only in conduct disorder. No differences in the levels of alpha-MSH-reactive autoAbs were found between aggressive and control subjects. CONCLUSIONS: High levels of ACTH-reactive autoAbs as well as altered levels of oxytocin- and vasopressin-reactive autoAbs found in aggressive subjects may interfere with the neuroendocrine mechanisms of stress and motivated behavior. Our data suggest a new biological mechanism of human aggressive behavior that involves autoAbs directed against several stress-related neurohormones. 相似文献
5.
6.
Sleep is a vital, highly organized process regulated by complex systems of neuronal networks and neurotransmitters. Sleep plays an important role in the regulation of central nervous system and body physiologic functions. Sleep architecture changes with age and is easily susceptible to external and internal disruption. Reduction or disruption of sleep can affect numerous functions varying from thermoregulation to learning and memory during the waking state. 相似文献
7.
A Watanabe K Ohizumi M Motomiya K Takeuchi T Yoshida S Ida Y Miura K Nishioka Y Tanno T Takishima 《The Japanese journal of antibiotics》1990,43(8):1392-1401
We evaluated the therapeutic efficacy of miconazole (MCZ, Florid-F inj.), a new antifungal agent for parenteral use, in deep-seated fungal infections of respiratory tract system. A daily dose of 400-1,800 mg of MCZ was given intravenously for 12-38 days (mean: 23.4 days) to 7 patients: 2 patients with pulmonary aspergillosis, 1 patient with bronchial aspergillosis, 1 patient with pulmonary candidiasis and 3 patients with candidemia. One additional patient with pulmonary aspergillosis received three instillations of 20 mg of MCZ into the thoracic cavity. The clinical effects were excellent in 1, good in 4 and poor in 3 patients. The efficacy rate was 100% in 5 cases with respiratory fungal infections but 3 cases with candidemia did not respond well to the treatment. Four strains each of Aspergillus sp. and Candida sp. were identified as causative organisms. Seven of the 8 strains were eradicated by administration of MCZ. Side effects observed were irritation and heat in a leg in 1 patient, hyperlipoidemia in 2 patients and eosinophilia in 1 patient. The adverse reactions disappeared after the completion of the therapy. From the above results, we conclude that MCZ is one of the most useful antifungal agents for parenteral use as a first choice on deep-seated fungal infections in the respiratory tract. 相似文献
8.
Ida Hellander 《Int J Health Serv》2002,32(3):579-599
This report presents data on the state of U.S. health care at the end of 2001. It provides information on access to health care, inequalities in incomes and medical care, the increasing costs of health care and health insurance, and the role of corporate money in the provision of health care and the development, marketing, and patenting of pharmaceuticals. The author also looks at the state of health maintenance organizations, the results of some recent surveys on physicians' and public opinion on managed care, and news about the nursing professions. Also provided is an update on Congressional activity on health care legislation, the role of health care industry money in politics, and some developments in health care systems elsewhere in the world. 相似文献
9.
Joan M. Farrell Ida A. Shaw 《Journal of behavior therapy and experimental psychiatry》2009,40(2):317-328
This study tests the effectiveness of adding an eight-month, thirty-session schema-focused therapy (SFT) group to treatment-as-usual (TAU) individual psychotherapy for borderline personality disorder (BPD). Patients (N = 32) were randomly assigned to SFT-TAU and TAU alone. Dropout was 0% SFT, 25% TAU. Significant reductions in BPD symptoms and global severity of psychiatric symptoms, and improved global functioning with large treatment effect sizes were found in the SFT-TAU group. At the end of treatment, 94% of SFT-TAU compared to 16% of TAU no longer met BPD diagnosis criteria (p < .001). This study supports group SFT as an effective treatment for BPD that leads to recovery and improved overall functioning. 相似文献
10.
Marina H C G Magalh?es Cristiane Barbosa da Silveira Carla Ruffeil Moreira Marcelo Gusm?o Paraíso Cavalcanti 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,103(6):836-842
Mandibulofacial dysostosis (Treacher Collins Syndrome) is an autosomal dominant genetic disorder that probably derives from inhibition of the facial structures from the first and second branchial arches. The facial pattern of the syndrome is a convex facial profile with a prominent nose above a retruded chin. The eyes are deformed by antimongoloid slant of the palpebral fissures and facial bones are hypoplastic. The alterations are caused by mutation in gene 5q32-33.1, which encodes the nucleolar phosphoprotein treacle. Computed tomography images are able to demonstrate craniofacial bones, allowing the morphological analysis of these bones in individuals with complex deformities. The purpose of this paper is to present the results of a clinical and computed tomography investigation of two patients with Treacher Collins syndrome. 相似文献