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Lapin Brittany R. Thompson Nicolas R. Schuster Andrew Honomichl Ryan Katzan Irene L. 《Quality of life research》2021,30(6):1735-1745
Quality of Life Research - Caregivers, or proxies, often complete patient-reported outcome measures (PROMs) on behalf of patients with stroke. The objective of our study was to assess the validity... 相似文献
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K Bork K Honomichl N Hoede 《Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete》1987,38(11):690-692
A hedgehog flea was the cause of multiple flea bites in a 48-year-old patient. The main host of the hedgehog flea is the European hedgehog, but the flea was also found in different furry mammals, such as polecats, brown rats and foxes. It was not previously known that Archaeopsylla erinacei attacks man. 相似文献
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Thompson Nicolas R. Katzan Irene L. Honomichl Ryan D. Lapin Brittany R. 《Quality of life research》2020,29(2):537-546
Quality of Life Research - Item response theory (IRT) scoring provides T-scores for physical and mental health subscales on the Patient-Reported Outcomes Measurement Information System Global... 相似文献
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Honomichl RD Goodlin-Jones BL Burnham M Gaylor E Anders TF 《Journal of autism and developmental disorders》2002,32(6):553-561
Data on sleep behavior were gathered on 100 children with pervasive developmental disorders (PDD), ages 2–11 years, using sleep diaries, the Children's Sleep Habits Questionnaire (CSHQ), and the Parenting Events Questionnaire. Two time periods were sampled to assess short-term stability of sleep–wake patterns. Before data collection, slightly more than half of the parents, when queried, reported a sleep problem in their child. Subsequent diary and CSHQ reports confirmed more fragmented sleep in those children who were described by their parents as having a sleep problem compared to those without a designated problem. Interestingly, regardless of parental perception of problematic sleep, all children with PDD exhibited longer sleep onset times and greater fragmentation of sleep than that reported for age-matched community norms. The results demonstrate that sleep problems identified by the parent, as well as fragmentation of sleep patterns obtained from sleep diary and CSHQ data, exist in a significant proportion of children with PDD. 相似文献
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Honomichl RD Goodlin-Jones BL Burnham MM Hansen RL Anders TF 《Child psychiatry and human development》2002,33(2):107-123
The objectives of this pilot study were 1) to examine possible effects of secretin infusions on sleep-wake state organization in children with autism, and 2) to assess the feasibility of home recordings using time-lapse videosomnography in children with autism. Participants were a subset of subjects from two double blind, placebo-control, multi-center clinical trials. One trial, the UC Irvine study, assessed the effects of porcine secretin vs. saline infusions on children's behavior, language and IQ. The UC Davis trial assessed the effects of synthetic human secretin vs. saline infusions on behavior, language and gastrointestinal function. The sleep study enrolled some of the children from each of the two trials to observe possible secretin effects on sleep. To examine sleep, the UC Irvine trial used the Children's Sleep Habits Questionnaire and daily sleep diaries, whereas the UC Davis study used home-recorded time-lapse videosomnography. Because of the small sample size, the results from both trials are preliminary. They suggest that secretin, porcine or synthetic, does not improve sleep-wake state organization dramatically. 相似文献
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Zubair Ahmed MD Ryan Honomichl PhD Stephen F. Thompson MS Joshua M. Cohen MD Andrew Schuster BA Nicolas R. Thompson MS Brittany Lapin PhD Belinda L. Udeh PhD Verena Ramirez Campos MD Lynda J. Krasenbaum MSN Irene L. Katzan MD 《Headache》2023,63(7):908-916
Objective
To describe differences in clinical and demographic characteristics between patients with episodic migraine (EM) or chronic migraine (CM) and determine the effect of migraine subtype on patient-reported outcome measures (PROM).Background
Prior studies have characterized migraine in the general population. While this provides a basis for our understanding of migraine, we have less insight into the characteristics, comorbidities, and outcomes of migraine patients who present to subspecialty headache clinics. These patients represent a subset of the population that bears the greatest burden of migraine disability and are more representative of migraine patients who seek medical care. Valuable insights can be gained from a better understanding of CM and EM in this population.Methods
We conducted a retrospective observational cohort study of patients with CM or EM seen in the Cleveland Clinic Headache Center between January 2012 and June 2017. Demographics, clinical characteristics, and patient-reported outcome measures (3-Level European Quality of Life 5-Dimension [EQ-5D-3L], Headache Impact Test-6 [HIT-6], Patient Health Questionnaire-9 [PHQ-9]) were compared between groups.Results
Eleven thousand thirty-seven patients who had 29,032 visits were included. More CM patients reported being on disability 517/3652 (14.2%) than EM patients 249/4881 (5.1%) and had significantly worse mean HIT-6 (67.3 ± 7.4 vs. 63.1 ± 7.4, p < 0.001) and median [interquartile range] EQ-5D-3L (0.77 [0.44–0.82] vs. 0.83 [0.77–1.00], p < 0.001), and PHQ-9 (10 [6–16] vs. 5 [2–10], p < 0.001).Conclusions
There are multiple differences in demographic characteristics and comorbid conditions between patients with CM and EM. After adjustment for these factors, CM patients had higher PHQ-9 scores, lower quality of life scores, greater disability, and greater work restrictions/unemployment. 相似文献
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