全文获取类型
收费全文 | 10692篇 |
免费 | 1395篇 |
国内免费 | 40篇 |
专业分类
耳鼻咽喉 | 56篇 |
儿科学 | 380篇 |
妇产科学 | 899篇 |
基础医学 | 976篇 |
口腔科学 | 77篇 |
临床医学 | 3765篇 |
内科学 | 1549篇 |
皮肤病学 | 182篇 |
神经病学 | 900篇 |
特种医学 | 142篇 |
外科学 | 808篇 |
综合类 | 76篇 |
一般理论 | 12篇 |
预防医学 | 1133篇 |
眼科学 | 94篇 |
药学 | 408篇 |
中国医学 | 3篇 |
肿瘤学 | 667篇 |
出版年
2023年 | 212篇 |
2022年 | 78篇 |
2021年 | 179篇 |
2020年 | 213篇 |
2019年 | 176篇 |
2018年 | 338篇 |
2017年 | 343篇 |
2016年 | 396篇 |
2015年 | 376篇 |
2014年 | 502篇 |
2013年 | 752篇 |
2012年 | 585篇 |
2011年 | 650篇 |
2010年 | 471篇 |
2009年 | 607篇 |
2008年 | 570篇 |
2007年 | 640篇 |
2006年 | 565篇 |
2005年 | 492篇 |
2004年 | 487篇 |
2003年 | 448篇 |
2002年 | 400篇 |
2001年 | 136篇 |
2000年 | 73篇 |
1999年 | 169篇 |
1998年 | 204篇 |
1997年 | 194篇 |
1996年 | 176篇 |
1995年 | 171篇 |
1994年 | 134篇 |
1993年 | 92篇 |
1992年 | 99篇 |
1991年 | 92篇 |
1990年 | 94篇 |
1989年 | 84篇 |
1988年 | 74篇 |
1987年 | 69篇 |
1986年 | 63篇 |
1985年 | 77篇 |
1984年 | 63篇 |
1983年 | 66篇 |
1982年 | 60篇 |
1981年 | 56篇 |
1980年 | 49篇 |
1979年 | 27篇 |
1978年 | 30篇 |
1977年 | 25篇 |
1976年 | 27篇 |
1974年 | 22篇 |
1973年 | 22篇 |
排序方式: 共有10000条查询结果,搜索用时 125 毫秒
1.
2.
Christopher D Hue Frances S Cho Siqi Cao Cameron R ”Dale” Bass David F Meaney Barclay Morrison III 《Journal of cerebral blood flow and metabolism》2015,35(7):1191-1198
Owing to the frequent incidence of blast-induced traumatic brain injury (bTBI) in recent military conflicts, there is an urgent need to develop effective therapies for bTBI-related pathologies. Blood-brain barrier (BBB) breakdown has been reported to occur after primary blast exposure, making restoration of BBB function and integrity a promising therapeutic target. We tested the hypothesis that treatment with dexamethasone (DEX) after primary blast injury potentiates recovery of an in vitro BBB model consisting of mouse brain endothelial cells (bEnd.3). DEX treatment resulted in complete recovery of transendothelial electrical resistance and hydraulic conductivity 1 day after injury, compared with 3 days for vehicle-treated injured cultures. Administration of RU486 (mifepristone) inhibited effects of DEX, confirming that barrier restoration was mediated by glucocorticoid receptor signaling. Potentiated recovery with DEX treatment was accompanied by stronger zonula occludens (ZO)-1 tight junction immunostaining and expression, suggesting that increased ZO-1 expression was a structural correlate to BBB recovery after blast. Interestingly, augmented ZO-1 protein expression was associated with specific upregulation of the α+ isoform but not the α− isoform. This is the first study to provide a mechanistic basis for potentiated functional recovery of an in vitro BBB model because of glucocorticoid treatment after primary blast injury. 相似文献
3.
Quality of life in stroke survivor–caregiver dyads: a new conceptual framework and longitudinal study protocol
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
4.
5.
6.
Gwyneth R. Milbrath MSN MPH RN Pamela B. DeGuzman PhD MBA RN 《Public health nursing (Boston, Mass.)》2015,32(4):349-358
Researchers interested in measuring neighborhood‐level effects should understand how “neighborhood” is defined within nursing sciences and other sciences, and the inherent strengths and weaknesses of current research methodologies. This concept analysis provides clarity around the concept of neighborhood within the context of health, analyzes the current state of development of the neighborhood concept, and proposes areas for future nursing research. Using the Rodger's Method of analysis, the concept of neighborhood within nursing and public health research is described based on existing literature. The concept's attributes, related concepts, antecedents, and consequences are given from the literature. Comparisons of the use of neighborhood are made between nursing, public health, sociology, and other sciences. The evolution of the concept of neighborhood throughout history is described, and important implications for future research are discussed. 相似文献
7.
8.
9.
10.