全文获取类型
收费全文 | 1217篇 |
免费 | 127篇 |
国内免费 | 53篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 40篇 |
妇产科学 | 15篇 |
基础医学 | 163篇 |
口腔科学 | 20篇 |
临床医学 | 184篇 |
内科学 | 283篇 |
皮肤病学 | 15篇 |
神经病学 | 87篇 |
特种医学 | 115篇 |
外科学 | 126篇 |
综合类 | 27篇 |
一般理论 | 3篇 |
预防医学 | 120篇 |
眼科学 | 8篇 |
药学 | 128篇 |
肿瘤学 | 62篇 |
出版年
2021年 | 21篇 |
2019年 | 14篇 |
2018年 | 20篇 |
2017年 | 20篇 |
2016年 | 33篇 |
2015年 | 19篇 |
2014年 | 33篇 |
2013年 | 37篇 |
2012年 | 37篇 |
2011年 | 38篇 |
2010年 | 31篇 |
2009年 | 21篇 |
2008年 | 45篇 |
2007年 | 69篇 |
2006年 | 39篇 |
2005年 | 50篇 |
2004年 | 36篇 |
2003年 | 33篇 |
2002年 | 43篇 |
2001年 | 32篇 |
2000年 | 30篇 |
1999年 | 36篇 |
1998年 | 36篇 |
1997年 | 39篇 |
1996年 | 26篇 |
1995年 | 31篇 |
1994年 | 26篇 |
1993年 | 23篇 |
1992年 | 21篇 |
1991年 | 34篇 |
1990年 | 22篇 |
1989年 | 35篇 |
1988年 | 30篇 |
1987年 | 23篇 |
1986年 | 25篇 |
1985年 | 24篇 |
1984年 | 19篇 |
1983年 | 14篇 |
1982年 | 12篇 |
1981年 | 11篇 |
1980年 | 14篇 |
1979年 | 18篇 |
1977年 | 19篇 |
1976年 | 16篇 |
1975年 | 12篇 |
1973年 | 16篇 |
1972年 | 14篇 |
1971年 | 9篇 |
1970年 | 10篇 |
1968年 | 16篇 |
排序方式: 共有1397条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
J Dow M A Petty J M Grisar E R Wagner K D Haegele 《Drug metabolism and disposition》1991,19(6):1040-1045
MDL74270 (6-acetyloxy-3,4-dihydro-N,N,N,2,5,7, 8-heptamethyl-2H-1-benzopyran-2-ethanaminium, 4-methylbenzenesulfonate) is a quaternary amine analogue of alpha-tocopherol with free radical scavenger properties. Rats were injected iv with [14C]MDL74270 (0.91 mg/kg), and whole blood and heart tissue were sampled. Five min after drug, the heart tissue/blood ratio (T/B) of radioactivity was 3.5, whereas at 1 hr it was 20.1 and remained at this value up to at least 6 hr. After iv administration the t 1/2 of radioactivity in blood was 6.3 hr, but po blood levels could not be quantified. The 0- to 96-hr urinary elimination of radioactivity was 39.9 +/- 5.7% of the dose after iv and only 1.2 +/- 0.4% after po administration, conversely, 44.7 +/- 5.2% was excreted in feces after iv and 79.1 +/- 17.4% after po administration. These results confirmed poor oral absorption of the compound. Tissue distribution of [14C]MDL74270 was compared with that of its tertiary amine analogue [14C]MDL74366 in rat heart, skeletal muscle, brain, and whole blood, after iv administration (1 mg/kg). The heart T/B was above 20, 1-6 hr after [14C]MDL74270, whereas it was less than 2 after [14C]MDL74366. Over the 1- to 6-hr time interval, skeletal muscle T/B varied from 1.8 to 5 compared with 1.5 to 0.6 for [14C] MDL74366. Brain T/B was higher after the tertiary amine compound. Results showed marked cardioselectivity of radioactivity after [14C] MDL74270. Differential centrifugation of heart homogenates showed that radioactivity was equally distributed between the major subcellular fractions studied.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
7.
Narrative and procedural discourse in temporal lobe epilepsy. 总被引:2,自引:0,他引:2
Brian Bell Christian Dow E Ryann Watson Austin Woodard Bruce Hermann Michael Seidenberg 《Journal of the International Neuropsychological Society》2003,9(5):733-739
It is well established that some individuals with temporal lobe epilepsy (TLE) demonstrate language deficits at the single word level. However, discourse production rarely has been examined quantitatively within this group. This study compared adult TLE patients with an early seizure onset (< or = age 14 years, n = 27) to a control group (n = 28) on narrative and procedural discourse tasks. As a group, the TLE patients performed normally on the procedural discourse task, but differed significantly from the controls on several narrative discourse variables. At the individual level, 30% of the TLE patients versus 4% of the controls demonstrated impaired discourse ability (p and 0.01). Within this early onset TLE group, discourse performance was not associated with demographic or seizure history variables. Considering the cognitive domain, discourse performance correlated significantly with working memory. In summary, mild discourse dysfunction was present in a significant minority of early onset TLE patients, but this deficit was not closely associated with other language measures. Discourse ability and its neuropsychological, neuroanatomical and conversational speech correlates deserve further study in TLE patients. 相似文献
8.
9.
Coralline hydroxyapatite bone graft substitutes: preliminary report of radiographic evaluation 总被引:1,自引:0,他引:1
A new bone graft substitute made by conversion of the calcium carbonate exoskeleton of reef-building sea coral into hydroxyapatite has recently become clinically available. The normal radiographic appearance of two forms of this material is described. In the immediate postoperative period, the exoskeletal architecture of these implants is readily appreciated. With graft incorporation over the ensuing months, their intrinsic structure is gradually lost in association with poor marginal definition. Evolving radiographic findings reflect the biocompatible nature of these implants, which provides the potential for ingrowth of native bone with preservation of the coralline scaffold, resulting in enhanced biomechanical properties. 相似文献
10.