全文获取类型
收费全文 | 7249篇 |
免费 | 405篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 64篇 |
儿科学 | 209篇 |
妇产科学 | 197篇 |
基础医学 | 782篇 |
口腔科学 | 103篇 |
临床医学 | 1055篇 |
内科学 | 1244篇 |
皮肤病学 | 65篇 |
神经病学 | 726篇 |
特种医学 | 181篇 |
外科学 | 859篇 |
综合类 | 68篇 |
一般理论 | 7篇 |
预防医学 | 877篇 |
眼科学 | 63篇 |
药学 | 481篇 |
中国医学 | 1篇 |
肿瘤学 | 689篇 |
出版年
2023年 | 45篇 |
2022年 | 66篇 |
2021年 | 162篇 |
2020年 | 111篇 |
2019年 | 166篇 |
2018年 | 190篇 |
2017年 | 144篇 |
2016年 | 181篇 |
2015年 | 188篇 |
2014年 | 221篇 |
2013年 | 341篇 |
2012年 | 506篇 |
2011年 | 538篇 |
2010年 | 288篇 |
2009年 | 243篇 |
2008年 | 379篇 |
2007年 | 388篇 |
2006年 | 414篇 |
2005年 | 445篇 |
2004年 | 367篇 |
2003年 | 369篇 |
2002年 | 299篇 |
2001年 | 112篇 |
2000年 | 100篇 |
1999年 | 126篇 |
1998年 | 65篇 |
1997年 | 51篇 |
1996年 | 42篇 |
1995年 | 42篇 |
1994年 | 37篇 |
1993年 | 40篇 |
1992年 | 80篇 |
1991年 | 65篇 |
1990年 | 61篇 |
1989年 | 47篇 |
1988年 | 48篇 |
1987年 | 53篇 |
1986年 | 70篇 |
1985年 | 58篇 |
1984年 | 42篇 |
1983年 | 49篇 |
1982年 | 25篇 |
1981年 | 30篇 |
1979年 | 42篇 |
1978年 | 29篇 |
1977年 | 19篇 |
1975年 | 25篇 |
1974年 | 16篇 |
1972年 | 21篇 |
1969年 | 17篇 |
排序方式: 共有7671条查询结果,搜索用时 15 毫秒
1.
Sarah E. Sheppard Laura Elizabeth Anderson Cathryn Sibbald Colleen Cotton Elizabeth Bhoj Marissa J. Perman Leslie Castelo‐Soccio 《Pediatric dermatology》2019,36(6):1007-1009
Epidermolysis bullosa simplex (EBS) is a skin fragility disorder resulting from mutations of structural proteins in the epidermis. We provide a brief report of long‐term survival and reproduction in a mother with EBS due to keratin 5 (KRT5) c.1429G > A (p.E477K) mutation, which causes a particularly severe form of the disease. 相似文献
2.
3.
4.
5.
6.
7.
Bone mineral density testing in healthy postmenopausal women. The role of clinical risk factor assessment in determining fracture risk. 总被引:5,自引:0,他引:5
William D Leslie Colleen Metge Elizabeth A Salamon C Kin Yuen 《Journal of clinical densitometry》2002,5(2):117-130
The ease of measurement and the quantitative nature of bone mineral densitometry (BMD) is clinically appealing. Despite BMD's proven capability to stratify fracture risk, data indicate that clinical risk factors provide complementary information on fracture susceptibility that is independent of BMD. Methods to quantify fracture risk using both clinical and BMD variables would have great appeal for clinical decision-making. We describe a procedure for quantifying hip fracture risk (5-yr and remaining lifetime) based on (1) the individual's age alone (base model, assuming average clinical risk factors and bone density), (2) incorporation of multiple patient-specific clinical risk factor data in the base model, and (3) incorporation of both patient-specific clinical risk factor data and BMD results. 相似文献
8.
Response rates,duration of response,and dose response effects in phase I studies of antineoplastics 总被引:4,自引:0,他引:4
Summary Over a period of 14 years, 7,960 patients were treated in 228 phase I trials. In these patients, there were 75 complete and 432 partial responses for an overall objective response rate of 6%. Complete responses lasted a median of six months (range 1–18), while partial responses lasted a median of three months (range 1–17). Of note is that no drug has made it to the market which has not had a response in phase I trials. Responses were noted in very diverse histologic types of tumors. Although there were responses at doses which were as low as 3–5% of the recommended dose for phase II trials, the majority of responses did occur at 80–120% of the dose recommended for phase II trials. Although the response rate in phase I trials is indeed low, responses do occur. This response rate information should help the clinician provide facts for the patient considering a phase I trial with new anticancer agents. These findings also emphasize that although phase I trials are characteristically dose-finding studies, if no responses are noted in phase I studies, it is unlikely the drug will be used routinely in the clinic. 相似文献
9.
10.
Brain morphology in first-episode schizophrenic-like psychotic patients: a quantitative magnetic resonance imaging study 总被引:5,自引:0,他引:5
L E DeLisi A L Hoff J E Schwartz G W Shields S N Halthore S M Gupta F A Henn A K Anand 《Neuropsychopharmacology》1991,29(2):159-175
Brain morphology was examined using magnetic resonance imaging in 30 first-episode patients with a schizophreniclike psychosis, 15 chronic schizophrenics, and 20 neurological controls. Statistical analyses of computer-generated measurements of regions of interest were controlled for gender, age, social class, and total brain volume. Lateral ventricular size was increased in both first-episode and chronic schizophrenic patients, with greater significance on the left than on the right side. Only the chronic patients, however, had reduced temporal lobe size, which also was greater on the left side. No major correlations of regional brain morphological measurements with cognitive functioning were found, although some measurements of verbal memory were correlated with parahippocampal size. This is a report of a preliminary study that suggests that some morphological brain changes may be present at the time of first treatment for a psychotic illness, whereas others may occur later in the course of illness. Future prospective studies may determine the clinical significance of these changes and whether they progress with the development of illness chronicity. 相似文献