收费全文 | 905469篇 |
免费 | 62867篇 |
国内免费 | 2339篇 |
耳鼻咽喉 | 12500篇 |
儿科学 | 28855篇 |
妇产科学 | 26255篇 |
基础医学 | 127390篇 |
口腔科学 | 24734篇 |
临床医学 | 75555篇 |
内科学 | 184115篇 |
皮肤病学 | 19051篇 |
神经病学 | 71992篇 |
特种医学 | 36641篇 |
外国民族医学 | 336篇 |
外科学 | 142651篇 |
综合类 | 19088篇 |
一般理论 | 259篇 |
预防医学 | 65385篇 |
眼科学 | 20281篇 |
药学 | 64391篇 |
中国医学 | 1805篇 |
肿瘤学 | 49391篇 |
2018年 | 9208篇 |
2017年 | 7288篇 |
2016年 | 7831篇 |
2015年 | 8888篇 |
2014年 | 12561篇 |
2013年 | 19520篇 |
2012年 | 26097篇 |
2011年 | 27715篇 |
2010年 | 16827篇 |
2009年 | 16001篇 |
2008年 | 26495篇 |
2007年 | 28127篇 |
2006年 | 28304篇 |
2005年 | 27815篇 |
2004年 | 26621篇 |
2003年 | 25778篇 |
2002年 | 25340篇 |
2001年 | 41438篇 |
2000年 | 42633篇 |
1999年 | 36344篇 |
1998年 | 10012篇 |
1997年 | 9182篇 |
1996年 | 9108篇 |
1995年 | 8479篇 |
1994年 | 8103篇 |
1993年 | 7618篇 |
1992年 | 28222篇 |
1991年 | 27001篇 |
1990年 | 26424篇 |
1989年 | 25363篇 |
1988年 | 23565篇 |
1987年 | 23182篇 |
1986年 | 22265篇 |
1985年 | 21168篇 |
1984年 | 15820篇 |
1983年 | 13493篇 |
1982年 | 8094篇 |
1979年 | 14603篇 |
1978年 | 10216篇 |
1977年 | 8631篇 |
1976年 | 8156篇 |
1975年 | 8964篇 |
1974年 | 10704篇 |
1973年 | 10186篇 |
1972年 | 9663篇 |
1971年 | 8921篇 |
1970年 | 8585篇 |
1969年 | 8028篇 |
1968年 | 7687篇 |
1967年 | 7089篇 |
Objectives
The current study investigated the effects of two exercise interventions on cognitive function amongst breast cancer survivors.Design
Pilot randomised-controlled trial.Methods
Seventeen female cancer survivors (mean: 62.9 ± 7.8 years) were randomised into three groups: high-intensity interval training (HIIT, n = 6); moderate-intensity continuous training (MOD, n = 5); or wait-list control (CON, n = 6). The HIIT and MOD groups exercised on a cycle ergometer 3 days/week for 12-weeks. Primary outcomes were cognitive function assessments utilising CogState. Secondary outcomes were resting middle cerebral artery blood flow velocity, cerebrovascular reactivity and aerobic fitness (VO2peak). Data were analysed with General Linear Mixed Models and Cohen’s d effect sizes were calculated.Results
All 17 participants who were randomised were available for follow-up analysis and adherence was similar for HIIT and MOD (78.7 ± 13.2% vs 79.4 ± 12.0%; p = 0.93). Although there were no significant differences in the cognitive and cerebrovascular outcomes, HIIT produced moderate to large positive effects in comparison to MOD and CON for outcomes including episodic memory, working memory, executive function, cerebral blood flow and cerebrovascular reactivity. HIIT significantly increased VO2peak by 19.3% (d = 1.28) and MOD had a non-significant 5.6% (d = 0.72) increase, compared to CON which had a 2.6% decrease.Conclusions
This study provides preliminary evidence that HIIT may be an effective exercise intervention to improve cognitive performance, cerebrovascular function and aerobic fitness in breast cancer survivors. Considering the sample size is small, these results should be confirmed through larger clinical trials. 相似文献Methods: A retrospective analysis was performed to identify patients with isolated PCL injuries that underwent reconstruction between 2001 and 2014. Patients with multi-ligamentous injury or another concomitant knee pathology were excluded. Medical records were reviewed for demographic, clinical and operative data. Patients were contacted for administration of a telephone-based questionnaire which included the International Knee Documentation Committee (IKDC) Subjective Knee Evaluation form, Lysholm-Tegner scales, Marx activity scale (MAS), return to sport status, and patient satisfaction instruments.
Results: A total of 15 isolated PCL reconstructions in 14 patients with a mean age of 27.5 years (range 17–43) met the study inclusion criteria; mean follow up was 6.3 years (range 1.4–15.2). Pre-operatively, the primary complaint was knee instability in all patients; on physical examination, lack of a firm end point during posterior drawer testing was found in 93% (14/15) of the knees. In total, 12 of 15 knees underwent transtibial, single-bundle PCLR and three of 15 underwent tibial inlay, double bundle PCLR. Graft types included: quadriceps autograft (7/15), Achilles allograft (6/15), and hamstring autograft (2/15). There were no graft failures in our patient cohort. At most recent follow up the mean scores respectively on the IKDC form, Lysholm-Tegner scales and MAS were (standard deviation): 77.3 (16.5), 83.1 (17.9), 6.13 (2.6), and 7.1 (6.0). All fourteen patients were athletes prior to their injury and 79% (11/14) returned to sport and overall patient satisfaction was 9.2/10.
Conclusions: Isolated PCLR provides good outcomes at mean medium-term follow up with restoration of function, high rate of return to sport and overall patient satisfaction. 相似文献