全文获取类型
收费全文 | 1102篇 |
免费 | 47篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 186篇 |
妇产科学 | 6篇 |
基础医学 | 124篇 |
口腔科学 | 14篇 |
临床医学 | 102篇 |
内科学 | 199篇 |
皮肤病学 | 17篇 |
神经病学 | 28篇 |
特种医学 | 174篇 |
外科学 | 119篇 |
综合类 | 16篇 |
预防医学 | 72篇 |
眼科学 | 5篇 |
药学 | 35篇 |
肿瘤学 | 53篇 |
出版年
2021年 | 9篇 |
2019年 | 6篇 |
2018年 | 11篇 |
2017年 | 9篇 |
2016年 | 6篇 |
2015年 | 14篇 |
2014年 | 22篇 |
2013年 | 23篇 |
2012年 | 18篇 |
2011年 | 20篇 |
2010年 | 34篇 |
2009年 | 31篇 |
2008年 | 27篇 |
2007年 | 24篇 |
2006年 | 18篇 |
2005年 | 33篇 |
2004年 | 28篇 |
2003年 | 29篇 |
2002年 | 31篇 |
2001年 | 26篇 |
2000年 | 31篇 |
1999年 | 28篇 |
1998年 | 40篇 |
1997年 | 32篇 |
1996年 | 30篇 |
1995年 | 32篇 |
1994年 | 30篇 |
1993年 | 23篇 |
1992年 | 20篇 |
1991年 | 21篇 |
1990年 | 26篇 |
1989年 | 28篇 |
1988年 | 35篇 |
1987年 | 31篇 |
1986年 | 22篇 |
1985年 | 36篇 |
1984年 | 19篇 |
1983年 | 27篇 |
1982年 | 31篇 |
1981年 | 21篇 |
1980年 | 13篇 |
1979年 | 16篇 |
1978年 | 20篇 |
1977年 | 19篇 |
1976年 | 22篇 |
1975年 | 15篇 |
1974年 | 9篇 |
1973年 | 9篇 |
1972年 | 5篇 |
1925年 | 4篇 |
排序方式: 共有1151条查询结果,搜索用时 31 毫秒
1.
2.
3.
Acute appendicitis: CT and US correlation in 100 patients 总被引:19,自引:1,他引:18
4.
Perforated colorectal neoplasms: correlation of clinical, contrast enema, and CT examinations 总被引:2,自引:0,他引:2
Hulnick DH; Megibow AJ; Balthazar EJ; Gordon RB; Surapenini R; Bosniak MA 《Radiology》1987,164(3):611-615
Results of clinical, contrast enema (CE), and computed tomographic (CT) examinations in 39 patients with perforated colorectal neoplasms were retrospectively reviewed. Twenty patients were toxemic at initial presentation, but in only four patients was the diagnosis of perforated colorectal neoplasm initially suspected clinically. CE study was performed in 22 patients and enabled the diagnosis of perforated neoplasm in 11 cases, neoplasm alone in eight, and neither neoplasm nor perforation in three. CT was performed in 38 patients and enabled the diagnosis of perforated neoplasm in 36; pericolic phlegmon but no mass lesion was evident in two. In 16 patients, CT also demonstrated metastatic disease. Because of its reliability in establishing the diagnosis and staging the extent of the inflammatory and neoplastic disease, CT is indicated in cases of suspected or proved perforated colorectal neoplasm and in cases in which CE study findings are indeterminate or suggestive of perforated neoplasm. 相似文献
5.
6.
Steenbergen EJ; Verhagen OJ; van Leeuwen EF; van den Berg H; von dem Borne AE; van der Schoot CE 《Blood》1995,86(2):692-702
Crosslineage T-cell receptor delta (TCR delta) rearrangements are widely used as tumor markers for the follow up of minimal residual disease in childhood B-precursor acute lymphoblastic leukemia (ALL) by polymerase chain reaction (PCR). The major drawback of this approach is the risk of false-negative results due to clonal evolution. We investigated the stability of V delta 2D delta 3 rearrangements in a group of 56 childhood B-precursor ALL patients by PCR and Southern blot analysis. At the PCR level, V delta 2D delta 3-to-J alpha rearranged subclones (one pathway for secondary TCR delta recombination) were demonstrated in 85.2% of V delta 2D delta 3-positive patients tested, which showed that small subclones are present in the large majority of patients despite apparently monoclonal TCR delta Southern blot patterns. Sequence analysis of V delta 2D delta 3J alpha rearrangements showed a biased J alpha gene usage, with HAPO5 and J alpha F in 26 of 32 and 6 of 32 clones, respectively. Comparison of V delta 2D delta 3 rearrangement status between diagnosis and first relapse showed differences in seven of eight patients studied. In contrast, from first relapse onward, no clonal changes were observed in six patients studied. To investigate the occurrence of crosslineage TCR delta rearrangements in normal B and T cells, fluorescence-activated cell sorter-sorted peripheral blood CD19+/CD3- and CD19-/CD3+ cell populations from three healthy donors were analyzed. V delta 2D delta 3 rearrangements were detected at low frequencies in both B and T cells, which suggests that V delta 2-to-D delta 3 joining also occurs during normal B-cell differentiation. A model for crosslineage TCR delta rearrangements in B-precursor ALL is deduced that explains the observed clonal changes between diagnosis and relapse and is compatible with multistep leukemogenesis of B-precursor ALL. 相似文献
7.
8.
9.
Israel Zelikovic Shermine Dabbagh Aaron L. Friedman David T. Uehling Russell W. Chesney 《Pediatric nephrology (Berlin, Germany)》1988,2(4):512-514
A boy aged 4.5 years with prune-belly syndrome (PBS) and associated urethral stenosis, oligohydramnios, imperforate anus and vesicosigmoid fustula is described. In contrast to the anticipated poor prognosis, vesicostomy and divided transverse colostomy performed after birth followed by prophylaxis of infection and bicarbonate supplementation have resulted in a good outcome. The vesicosigmoid fistula might have served in utero as a natural diversion protecting from pressure-induced renal damage. It is suggested that the main determinant of prognosis in PBS is the presence and degree of kidney dysplasia at birth as reflected by the neonatal renal function after performance of an indicated urinary diversion procedure rather than the presence of severe associated anomalies.Supported in part by grants from the National Institute of Health AM 37223-01 and the Medical School and Graduate School Research Committees of the University of Wisconsin and a Research Career Development Award KO4 AM 00421 (RWC), by the Pearl M. Stetler Foundation (SD) and by a National Kidney Foundation fellowship (IZ) 相似文献
10.