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排序方式: 共有446条查询结果,搜索用时 15 毫秒
1.
Del Lama Rafael Silva Candido Raquel Mariana Chiari-Correia Natália Santana Nogueira-Barbosa Marcello Henrique de Azevedo-Marques Paulo Mazzoncini Tinós Renato 《Journal of digital imaging》2022,35(3):446-458
Journal of Digital Imaging - Vertebral Compression Fracture (VCF) occurs when the vertebral body partially collapses under the action of compressive forces. Non-traumatic VCFs can be secondary to... 相似文献
2.
A Morales M C Torres J L Megias A Candido A Maldonado 《Pharmacology, biochemistry, and behavior》1992,43(1):153-157
The effect of administration of diazepam on successive negative contrast in one-way avoidance learning was examined in rats. Contrast was induced by shifting rats from a large reward, 30 s spent in the safe compartment, to a small reward, 1 s spent in the safe compartment. IP administration of 2 mg/kg diazepam eliminated this negative contrast. Moreover, this effect is dose dependent, with doses of 2 and 2.5 mg/kg, but not 0.5 mg/kg, effective in reliably reducing contrast. These results suggest the existence of similar or common underlying mechanisms in both aversive and appetitive contrast effects; they are discussed in light of the current theories of frustrative nonreward and as a mean of studying the behavioral and biological mechanisms of anxiety. 相似文献
3.
Pedro Magno José Loureiro Alexandre Marques Pedro Farto E Abreu Machado Candido Paulo Leal Victor M Gil 《Revista portuguesa de cardiologia》2007,26(10):1033-1042
Ischemic stroke occurs in 0.2-0.4% of patients undergoing left heart catheterization, and is responsible for 5-10% of the mortality associated with the procedure. The main predisposing factors for this complication are female gender, complex atherosclerotic plaques in the ascending aorta, and peripheral arterial disease. The possibility of timely intervention with reperfusion therapy supports close clinical monitoring during the immediate post-catheterization period. The cardiologist should be familiar with the various types of stroke reperfusion therapy and its indications according to the time interval between catheterization and the stroke. The decision should be discussed with neurology and neuroradiology. 相似文献
4.
The initiation of a reentrant circuit requires a zone of slow conduction and a zone of unidirectional block. This study used
computer model conditions under which partial coupling between segments of cardiac Purkinje tissue resulted in unidirectional
block. The structure used was one-dimensional and divided into three segments: a middle segment of variable length coupled
to two long (semi-infinite in concept) segments. The DiFrancesco-Noble equations represented the ionic currents of the membrane.
The results show that the possibility of unidirectional block depends on the size of the middle segment and the coupling resistances
between the segments. No combination of coupling resistances allowed unidirectional block for middle segments with a length
of two space constants (4 mm) or longer. Unidirectional block occurred for many combinations of coupling resistances as the
length of the middle segment decreased to around half a space constant (1 mm). The number of length combinations that caused
unidirectional block decreased again as segment length further decreased. These results provide a possible mechanism of unidirectional
block for situations where islands of viable tissue are connected through nonviable tissue, such as in a healed myocardial
infarction. 相似文献
5.
Liz Nayibe Martínez Saavedra Ricardo Gonalves Penido Lucas de Azevedo Santos Teodorico C. Ramalho Bruno E. Lobo Baeta Mrcio C. Pereira Adilson Candido da Silva 《RSC advances》2018,8(50):28775
The effects of solvent on the synthesis of molecularly imprinted polymers (MIPs) for the selective adsorption of quinoline were evaluated in this work. The MIPs were synthesized by the “bulk” method using the quinoline molecule (IQ) as a template in different solvents, such as toluene (MIPT) and chloroform (MIPC). The adsorbents were characterized by thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), and N2 adsorption/desorption measurements. The influences of time, adsorbate concentration, and temperature on the adsorption of quinoline by MIPT and MIPC were evaluated. Maximum adsorption capacities (qe) of 35.23 and 24.10 mg g−1 were obtained for MIPT and MIPC, respectively. Thermodynamic studies indicate that occur physisorption and a spontaneous process (ΔadsG° < 0) entropically directed. Finally, the highest selectivity and reusability of MIPC for quinoline adsorption was ascribed to the better interaction between the chloroform and monomer, which favors the formation of porous adsorbents with higher numbers of adsorption sites.Molecularly imprinted polymers synthesized by a one-pot synthesis absorb quinoline efficiently and selectively. 相似文献
6.
Candido R Forbes JM Thomas MC Thallas V Dean RG Burns WC Tikellis C Ritchie RH Twigg SM Cooper ME Burrell LM 《Circulation research》2003,92(7):785-792
The formation of advanced glycation end products (AGEs) on extracellular matrix components leads to accelerated increases in collagen cross linking that contributes to myocardial stiffness in diabetes. This study determined the effect of the crosslink breaker, ALT-711 on diabetes-induced cardiac disease. Streptozotocin diabetes was induced in Sprague-Dawley rats for 32 weeks. Treatment with ALT-711 (10 mg/kg) was initiated at week 16. Diabetic hearts were characterized by increased left ventricular (LV) mass and brain natriuretic peptide (BNP) expression, decreased LV collagen solubility, and increased collagen III gene and protein expression. Diabetic hearts had significant increases in AGEs and increased expression of the AGE receptors, RAGE and AGE-R3, in association with increases in gene and protein expression of connective tissue growth factor (CTGF). ALT-711 treatment restored LV collagen solubility and cardiac BNP in association with reduced cardiac AGE levels and abrogated the increase in RAGE, AGE-R3, CTGF, and collagen III expression. The present study suggests that AGEs play a central role in many of the alterations observed in the diabetic heart and that cleavage of preformed AGE crosslinks with ALT-711 leads to attenuation of diabetes-associated cardiac abnormalities in rats. This provides a potential new therapeutic approach for cardiovascular disease in human diabetes. 相似文献
7.
Ana Railka de Souza Oliveira Alice Gabrielle de Sousa Costa Huana Carolina Candido Morais Tahissa Frota Cavalcante Marcos Venícios de Oliveira Lopes Thelma Leite de Araujo 《Revista latino-americana de enfermagem》2015,23(2):216-224
Objective:
to investigate the association of risk factors with the Risk for aspiration nursing diagnosis and respiratory aspiration.Method:
cross-sectional study assessing 105 patients with stroke. The instrument used to collect data addressing sociodemographic information, clinical variables and risk factors for Risk for aspiration. The clinical judgments of three expert RNs were used to establish the diagnosis. The relationship between variables and strength of association using Odds Ratio (OR) was verified both in regard to Risk for aspiration and respiratory aspiration.Results:
risk for aspiration was present in 34.3% of the patients and aspiration in 30.5%. The following stood out among the risk factors: Dysphagia, Impaired or absent gag reflex, Neurological disorders, and Impaired physical mobility, all of which were statistically associated with Risk for aspiration. Note that patients who develop such a diagnosis were seven times more likely to develop respiratory aspiration.Conclusion:
dysphagia, Impaired or absent gag reflex were the best predictors both for Risk for aspiration and respiratory aspiration. 相似文献8.
9.
Rossana de Araújo Cat?o Zampronha Ruffo Freitas-Junior Eddie Fernando Candido Murta Márcia Antoniazi Michelin Aline Almeida Barbaresco Sheila Jorge Adad Amaurillo Monteiro de Oliveira Amanda B. Rassi Glória Jabur Bittar Oton 《Clinics (S?o Paulo, Brazil)》2013,68(6):809-814
OBJECTIVE:
This study sought to evaluate the prevalence of human papillomavirus (HPV) types 16 and 18 in women with clinical stage IB cervical cancer treated by radical hysterectomy with pelvic lymphadenectomy as well as to establish a correlation between HPV type and cancer prognosis.METHODS:
A single-center cohort study was conducted with 86 patients who had undergone radical hysterectomy for stage I cervical cancer. Prognostic factors and the presence of HPV 16 and 18 were analyzed using a polymerase chain reaction assay. A univariate analysis using Kaplan-Meier curves was conducted to estimate survival.RESULTS:
The prevalence of HPV 16 in the study group was 65.3%, and the prevalence of HPV 18 was 33.3%. The prevalence of infection with both viruses was 26.9%. Overall survival at 5 years was 91% among women with HPV 18 and 96% among those without this virus type (p = 0.133). Among the women with HPV 16, the overall survival was 94%, whereas this rate was 96% among those without this virus type (p = 0.663). Disease-free survival was unaffected by the presence of HPV type 16 or 18.CONCLUSION:
In the present study, despite the high prevalence of HPV types 16 and 18, the presence of these virus types did not affect the prognosis of patients with stage I cervical cancer who underwent radical hysterectomy. 相似文献10.