全文获取类型
收费全文 | 686篇 |
免费 | 46篇 |
国内免费 | 67篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 53篇 |
妇产科学 | 3篇 |
基础医学 | 83篇 |
口腔科学 | 47篇 |
临床医学 | 82篇 |
内科学 | 156篇 |
皮肤病学 | 4篇 |
神经病学 | 19篇 |
特种医学 | 117篇 |
外科学 | 39篇 |
综合类 | 18篇 |
预防医学 | 80篇 |
眼科学 | 6篇 |
药学 | 57篇 |
中国医学 | 5篇 |
肿瘤学 | 18篇 |
出版年
2023年 | 2篇 |
2022年 | 6篇 |
2021年 | 7篇 |
2020年 | 13篇 |
2019年 | 6篇 |
2018年 | 15篇 |
2017年 | 15篇 |
2016年 | 19篇 |
2015年 | 14篇 |
2014年 | 17篇 |
2013年 | 23篇 |
2012年 | 44篇 |
2011年 | 36篇 |
2010年 | 22篇 |
2009年 | 22篇 |
2008年 | 27篇 |
2007年 | 57篇 |
2006年 | 22篇 |
2005年 | 18篇 |
2004年 | 19篇 |
2003年 | 20篇 |
2002年 | 28篇 |
2001年 | 26篇 |
2000年 | 13篇 |
1999年 | 14篇 |
1998年 | 26篇 |
1997年 | 30篇 |
1996年 | 26篇 |
1995年 | 18篇 |
1994年 | 20篇 |
1993年 | 11篇 |
1992年 | 5篇 |
1991年 | 11篇 |
1990年 | 14篇 |
1989年 | 17篇 |
1988年 | 17篇 |
1987年 | 12篇 |
1986年 | 12篇 |
1985年 | 17篇 |
1984年 | 4篇 |
1983年 | 7篇 |
1982年 | 8篇 |
1981年 | 8篇 |
1980年 | 5篇 |
1978年 | 7篇 |
1977年 | 4篇 |
1976年 | 5篇 |
1975年 | 7篇 |
1970年 | 2篇 |
1967年 | 1篇 |
排序方式: 共有799条查询结果,搜索用时 15 毫秒
1.
2.
The advantages of the new, safer, but more expensive iodinated contrast agents are discussed, and opinions on which patient groups should receive the agents are presented. 相似文献
3.
4.
Dalton A Anjos Elba C S C Etchebehere Celso D Ramos Allan O Santos César Albertotti Edwaldo E Camargo 《Journal of nuclear medicine》2007,48(5):764-770
PET with (18)F-FDG has been considered of limited value for detection of bladder cancer because of the urinary excretion of the tracer. The purpose of this study was to investigate the role of PET/CT in the detection and restaging of bladder cancer using furosemide and oral hydration to remove the excreted (18)F-FDG from the bladder. METHODS: Seventeen patients with bladder cancer (11 without cystectomy, 6 with total cystectomy and urinary diversion) underwent (18)F-FDG PET/CT from head to the upper thighs 60 min after the intravenous injection of 370 MBq of (18)F-FDG. Additional pelvic images were acquired 1 h after the intravenous injection of furosemide and oral hydration. PET/CT findings were confirmed by MRI, cystoscopy, or biopsy. RESULTS: PET/CT was able to detect bladder lesions in 6 of 11 patients who had not undergone cystectomy. These images changed the PET/CT final reading in 7 patients: Recurrent bladder lesions were detected in 6 patients, pelvic lymph node metastases in 2 patients, and prostate metastasis in 1. This technique overcame the difficulties posed by the urinary excretion of (18)F-FDG. Hypermetabolic lesions could be easily detected by PET and precisely localized in the bladder wall, pelvic lymph nodes, or prostate by CT. Seven of 17 patients (41%) were upstaged only after delayed pelvic images. CONCLUSION: Detection of locally recurrent or residual bladder tumors can be dramatically improved using (18)F-FDG PET/CT with delayed images after a diuretic and oral hydration. 相似文献
5.
A modified technique for catheterization of the pulmonary artery was developed. It involves the passage of a tapered, movable-core, J-tipped guide wire across the right ventricle into the pulmonary artery followed by the advancement of a straightened Grollman pigtail catheter. The technique was successful in 34 of 34 pulmonary artery catheterizations. The method avoids prolonged catheter manipulation within the right ventricle. In addition, since the catheter does not cross the tricuspid valve until the guide wire has been advanced, the occasional complication of the pigtail "hooking" on a tricuspid valve leaflet or chordae tendineae during catheter withdrawal and manipulation is prevented. 相似文献
6.
L A dos Anjos 《Revista de saúde pública》1989,23(3):221-229
The growth and nutritional status of 185 school-aged children (97 boys and 88 girls) of low socio-economic level in Nova Igua?ú, State of Rio de Janeiro, Brazil, were studied. Nutritional anthropometry identified 3.52 and 6.25% of the children as suffering from wasting and stunting, respectively. These prevalences of malnutrition were comparable to those described in pre-school children living in a "favela" (shanty town) of Rio de Janeiro. In general, the median height fell below the 25th centile of the international standard of growth. The value of 10 year-old boys fell below the 10th centile. The mean values of weight and height of these children were comparable to those of children from the Northeastern region of Brazil ("Nordeste"), higher than those found for children in the State of Paraíba, Brazil, and lower than those for middle-class children of the State of S. Paulo. Skinfold thickness, arm circumference, and arm fat area data were higher in girls than boys. However, arm muscle are values in boys were superior in comparison to those of girls. 相似文献
7.
8.
Comparison of C(18)-carboxypropylbetaine and standard N-acetyl-L-cysteine-NaOH processing of respiratory specimens for increasing tuberculosis smear sensitivity in Brazil
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Scott CP Dos Anjos Filho L De Queiroz Mello FC Thornton CG Bishai WR Fonseca LS Kritski AL Chaisson RE Manabe YC 《Journal of clinical microbiology》2002,40(9):3219-3222
Techniques to improve the sensitivity of smear microscopy would facilitate early tuberculosis (TB) diagnosis and disease control, especially in low-income countries where the positive predictive value is high. C(18)-carboxypropylbetaine (CB-18) is a zwitterionic detergent that helps to compensate for the innate buoyancy of mycobacteria, potentially enhancing recovery by centrifugation. Previous data suggest that CB-18 may increase the sensitivity of smear, culture, and molecular amplification diagnostic testing. The goal of the present study was to evaluate if the sensitivity of the smear technique using light microscopy could be improved by treating respiratory samples with CB-18. In the first phase, respiratory specimens were collected consecutively from patients with suspected pulmonary tuberculosis in a tertiary-care hospital in Rio de Janeiro, Brazil (236 specimens were analyzed). After protocol modifications, another 120 respiratory specimens were evaluated. The standard technique was N-acetyl-L-cysteine with sodium hydroxide (NALC-NaOH) treatment, smear concentration with centrifugation, and Ziehl-Neelsen staining. Culture on L?wenstein-Jensen slants was performed on all specimens for use as the "gold standard." No specimens from patients undergoing active TB treatment were included. The initial protocol for CB-18 processing resulted in a sensitivity of 59.6% and specificity of 96.8% compared to standard processing with a sensitivity of 66.0% and specificity of 96.8%. Using the modified protocol, the sensitivity of CB-18 increased to 71.4% with a specificity of 97.0% versus standard processing with a sensitivity of 61.9% and a specificity of 99.0%. The diagnostic yield of acid-fast bacillus smear with CB-18 in the absence of fluorescence microscopy and PCR compared to standard processing with NALC-NaOH was not significantly different, although the power to detect a difference by the modified assay was low. 相似文献
9.
乳腺管状小叶癌(Tubulolobular carcinoma,TLC)最初是被作为小叶癌的管状变型。作者总结了27例TLC的组织学、免疫表型和临床特征,并与纯小管癌和经典型小叶癌进行了比较。此组患者年龄43-79岁(中位年龄60岁)。1例双侧乳腺受累,5例病变为多灶性。肿瘤直径0.5-2.5cm,色灰褐,质硬。组织学观察:TLC的肿瘤细胞形成管状和条索状两种结构模式并相互混杂,且两者比例相当(统称为管状小叶模式)。 相似文献
10.