全文获取类型
收费全文 | 8560篇 |
免费 | 497篇 |
国内免费 | 47篇 |
专业分类
耳鼻咽喉 | 76篇 |
儿科学 | 186篇 |
妇产科学 | 151篇 |
基础医学 | 1038篇 |
口腔科学 | 119篇 |
临床医学 | 621篇 |
内科学 | 2410篇 |
皮肤病学 | 94篇 |
神经病学 | 892篇 |
特种医学 | 208篇 |
外科学 | 1028篇 |
综合类 | 61篇 |
一般理论 | 8篇 |
预防医学 | 609篇 |
眼科学 | 308篇 |
药学 | 598篇 |
1篇 | |
中国医学 | 28篇 |
肿瘤学 | 668篇 |
出版年
2023年 | 51篇 |
2022年 | 116篇 |
2021年 | 266篇 |
2020年 | 138篇 |
2019年 | 246篇 |
2018年 | 259篇 |
2017年 | 198篇 |
2016年 | 197篇 |
2015年 | 211篇 |
2014年 | 285篇 |
2013年 | 451篇 |
2012年 | 648篇 |
2011年 | 628篇 |
2010年 | 365篇 |
2009年 | 336篇 |
2008年 | 574篇 |
2007年 | 618篇 |
2006年 | 587篇 |
2005年 | 525篇 |
2004年 | 435篇 |
2003年 | 432篇 |
2002年 | 419篇 |
2001年 | 97篇 |
2000年 | 73篇 |
1999年 | 62篇 |
1998年 | 84篇 |
1997年 | 63篇 |
1996年 | 49篇 |
1995年 | 44篇 |
1994年 | 33篇 |
1993年 | 26篇 |
1992年 | 46篇 |
1991年 | 38篇 |
1990年 | 29篇 |
1989年 | 36篇 |
1988年 | 38篇 |
1987年 | 37篇 |
1986年 | 21篇 |
1985年 | 27篇 |
1984年 | 19篇 |
1983年 | 14篇 |
1982年 | 25篇 |
1981年 | 31篇 |
1980年 | 20篇 |
1979年 | 16篇 |
1978年 | 18篇 |
1977年 | 12篇 |
1976年 | 14篇 |
1974年 | 14篇 |
1973年 | 12篇 |
排序方式: 共有9104条查询结果,搜索用时 15 毫秒
1.
Maria Gonzalez-Cao Cristina Carrera Juan Francisco Rodriguez Moreno Pedro Rodríguez-Jiménez Mónica Antoñanzas Basa Rosa Feltes Ochoa Teresa Puertolas Eva Muñoz-Couselo José Luis Manzano Ivan Marquez-Rodas Juan Martín-Liberal Ainara Soria Pilar Lopez Criado Almudena Garcia-Castaño Aram Boada Pablo Ayala de Miguel Susana Puig Guillermo Crespo Alfonso Berrocal 《Journal of the American Academy of Dermatology》2021,84(5):1412-1415
2.
Psychological characteristics and physiological reactivity to acute stress in mothers of children with autism spectrum disorder 总被引:1,自引:0,他引:1
Elena Pattini Luca Carnevali Alfonso Troisi Guido Matrella Dolores Rollo Mauro Fornari Andrea Sgoifo 《Stress and health》2019,35(4):421-431
Stress related to parenting a child with autism spectrum disorder can differently affect caregiver's physiological reactivity to acute stress. Here, parental stress levels, psychological characteristics, and coping strategies were assessed alongside measures of heart rate, heart rate variability, and cortisol during a psychosocial stress test in mothers of children with ASD (M‐ASD, n = 15) and mothers of typically developing children (n = 15). M‐ASD reported significantly higher levels of parental stress, anxiety, negative affectivity, social inhibition, and a larger preference for avoidance strategies. M‐ASD showed larger heart rate and cortisol responses to the psychosocial stress test. A positive relationship was found between parental stress levels and the magnitude of the cortisol stress response in both groups. The present findings indicate exaggerated physiological reactivity to acute psychosocial stress in M‐ASD and prompt further research to explore the role of individual differences in mediating the effects of parental stress on physiological stress responses. 相似文献
3.
Aureli Torné Alfonso Alba Xavier Castellsagué Javier Cortés 《Progresos de Obstetricia y Ginecología》2006
Persistent infection by human papilloma virus (HPV) is considered to be the main cause of cervical cancer and other ano-genital cancers. Of more than 30 genotypes able to infect the anogenital tract, it is estimated that, worldwide, HPV 16 and 18 cause 70% of cervical cancers and that HPV 6 and 11 cause more than 90% of genital warts. In the last few years, the morbidity and mortality and health costs associated with cervical cancer and its precursor lesions have stimulated intense research activity to achieve primary prevention of this disease through prophylactic vaccines. 相似文献
4.
Morphological and biochemical studies of a mouse mutant (fro/fro) with bone fragility. 总被引:4,自引:0,他引:4
The mutation fragilitas ossium (fro) was discovered in a random-bred stock of mice during an experiment aimed at detecting recessive lethal mutations after treatment of the postmeiotic germ cells of male mice with tris (1-aziridinyl)phosphine sulphide. The affected mice were moderately runted and had deformities in all four limbs. The radiological and histological findings indicate that the mutant is similar to human osteogenesis imperfecta. The ash content of long bones was lower in the mutant. A defect of type I collagen could not be detected. The electrophoretic patterns of alpha bands of type I and V collagen and CB derived peptides of type I collagen from bone and skin showed no abnormalities. The total collagen synthesis and secretion in cultures of dermal fibroblasts, as well as the gel electrophoresis of procollagen and collagen chains synthesized, and of their CB peptides, were the same as those found in the controls. The percentage of type I and type V collagen synthesized was similar; that of type III was lower in the mutants. Bone osteonectin was found to be decreased by 30% and bone sialoprotein by 5%. The mRNA level for osteonectin was decreased in the fibroblasts of the mutant by about 50%. Whether the defective expression of the osteonectin in fro/fro mice is due to a mutation in the gene itself or its regulatory site(s), or is secondary to other factors remains to be established. The fro/fro mouse may represent a model for some forms of human bone fragility without collagen abnormalities. 相似文献
5.
6.
7.
Esparza-Gordillo Jorge; Goicoechea de Jorge Elena; Buil Alfonso; Berges Luis Carreras; Lopez-Trascasa Margarita; Sanchez-Corral Pilar; Rodriguez de Cordoba Santiago 《Human molecular genetics》2005,14(8):1107
Some MCP SNP and aHUS-associated MCP mutation 相似文献
8.
Muriel Mitcheson Brown 《British Journal of Psychotherapy》2006,22(4):463-470
ABSTRACT Freud's paper on the Schreber Case is considered from a contemporary perspective drawing on the object relations theorists. Some of Winnicott's ideas are used to illustrate how one might understand Schreber's predicament today. Although Freud's views on the role of repressed homosexual longings in the aetiology of Schreber's illness are not endorsed his prescience in the search for meaning in the patient's discourse is applauded. 相似文献
9.
10.
Ruben A. Mesa MD Alfonso Quintás-Cardama MD Srdan Verstovsek MD PhD 《Current hematologic malignancy reports》2007,2(1):25-33
Myelofibrosis with myeloid metaplasia (MMM) is currently classified as a classic (ie, BCR-ABL-negative) myeloproliferative
disorder characterized by anemia, multiorgan extramedullary hematopoiesis, constitutional symptoms, and premature death from
either leukemic transformation or other disease complications. Stem cell transplantation can be curative, but many patients
either are not appropriate candidates or do not choose to accept the significant risks associated with transplantation. Current
pharmacologic therapy has been beneficial mainly in terms of palliating disease-associated cytopenias, constitutional symptoms,
splenomegaly, and other organ damage from excess myeloproliferation. Novel treatment strategies are under investigation, including
targeted inhibition of JAK2V617F, the activating tyrosine kinase point mutation present in about half of patients with MMM. In this article, we review both
the old and new pharmacologic options for MMM. 相似文献