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Objective
To explore the clinical effects of electroacupuncture (EA) at Zusanli (ST 36) and Fenglong (ST 40) in treating senile dementia.Methods
A total of 74 patients were randomly divided into an EA group and a medication group based upon the random digital table, 37 cases in each group. EA at Zusanli (ST 36) and Fenglong (ST 40) was given in the EA group, once every day, for six treatments per week. Donepezil Hydrochloride Tablets were given to the medication group, 5 mg per time and once a day in the former four weeks, 10 mg per time and once a day after 4 weeks, oral administration before sleep at night. The courses of the treatment were 12 weeks in both groups. The scores of mini-mental state examination (MMSE) and Barthel index (BI) were observed before and after the treatment, for processing the comparative analysis of the clinical effects after the course of the treatment.Results
The total effective rate was 86.5% in the EA group and 70.3% in the medication group. The therapeutic effect was better in the EA group than that in the medication group, and the difference between the two groups was statistically significant (P<0.05). MMSE and BI scores after the treatment in the two groups were all elevated than those of the same groups before the treatment (P<0.05, P<0.01). The improving situation was obviously better in the EA group than that in the medication group, and the difference between the two groups was statistically significant (P<0.05).Conclusion
EA at Zusanli (ST 36) and Fenglong (ST 40) is affirmative in the therapeutic effect for senile dementia and can also improve the cognitive function and enhance the patients’ quality of life.5.
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我们与兄弟单位协作,在中药当归芦荟丸治疗慢性粒细胞性白血病(以下简称慢粒)有效的基础上,从中筛选到有效中药青黛。1974年9月至1977年1月期间,我院用青黛治疗慢粒病人17例,至1978年8月时,17例中已死亡者5例,其余12例在最近一次随访时仍存活。17例的平均生存时间已有38.7个月,中数生存期将超过35个月。现简单介绍青黛治疗慢粒17例的情况于下。治疗药物一、青黛是常用中药,味成性寒,入肝经,功能泻肝经实火,散郁火,清热解毒,凉血止血,消斑,治疮疡。青黛是用大青叶作原料在制靛过程中所得到的副产品。大青叶的品种甚复杂,常用者有 相似文献
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我们从多种靛玉红衍生物中筛选出治疗慢粒有效药物N′-乙酰靛玉红。用N′-乙酰靛玉红治疗慢粒27例,完全缓解12例(44.44%),部份缓解14例(51.85%),进步1例(3.71%),缓解率96.29%,有效率100%,治疗9.52±6.20天后脾脏开始缩小,19.62±12.22天外周血白细胞数开始下降;达到最佳疗效(缓解)平均为87.62天,最短28天,最长206天;有5例出现腹胀、腹痛、大便次数增多,食欲不振等反应,但都能坚持用药,本组病例已发生急变者9例(33.3%)。临床研究结果表明,N′-乙酰靛玉红对慢粒具有良好疗效,不良反应轻微,优于靛玉红,值得进一步研究。 相似文献
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Objective
To observe the effect of herbal cake-partitioned moxibustion on the expressions of mitogen-activated protein kinase (MEK1/2) and extracellular regulatory protein kinase (ERK1/2) in gastric tissues of rats with spleen deficiency syndrome, and to explore the possible mechanisms of herbal cake-partitioned moxibustion in treating spleen deficiency syndrome.Methods
Sixty Sprague-Dawley (SD) rats were randomly divided into a blank control group (group A), a model group (group B), a ranitidine group (group C), and a herbal cake-partitioned moxibustion group (group D) by random digit, 15 rats in each group. Rat models of spleen deficiency syndrome were made by intragastric administration of 4 °C 200% concentrated Da Huang (Radix et Rhizoma Rhei). After successful modeling, the rats in group C were treated with 25 mg/(kg·bw) ranitidine by intragastric adminstration and rats in group D were treated with herbal cake-partitioned moxibustion at Zusanli (ST 36) and Zhongwan (CV 12), for 8 d. Excepted for rats in group A, all the other rats were treated with indomethacin at 5 mg/(kg·bw) at 8:00 a.m. on the second day after finishing all the intervention and sacrificed 7 h later to isolate the stomach. Histopathological changes of the gastric tissues were observed under light microscope after hematoxylin-eosin (HE) staining. The protein expressions of MEK1/2 and ERK1/2 in the gastric tissues were detected by immunohistochemistry.Results
After intervention, the gastric mucosal injury in group B was significantly severer than that in group A, with large breakage and ablating; the damage of gastric mucosa was decreased in group C compared with group B; the gastric mucosal surface remained relatively complete, and the status of breakage and ablating was significantly improved. After intervention, compared with group A, the protein expressions of MEK1/2 and ERK1/2 in gastric tissues of the other groups were significantly higher (P<0.01). Compared with group B, the protein expressions of MEK1/2 and ERK1/2 in group C and D were significantly higher (all P<0.01). Compared with group C, the protein expressions of MEK1/2 and ERK1/2 in group D were significantly higher (P<0.01).Conclusion
Herbal cake-partitioned moxibustion promotes the repair of gastric mucosa in rats with spleen deficiency syndrome, via improving protein expressions of MEK1/2 and ERK1/2 in gastric tissues, as well as activating MEK/ERK signaling pathway.10.
马明珠 《江苏卫生事业管理》2016,(2):92-93
随着信息技术的快速发展,信息技术已成为人们生产和生活的重要组成部分,同时也对医院党建管理方式的变化产生了巨大的影响,笔者在长期的医院党建实践中,探索利用现代信息技术优势,创新医院党建工作方式,取得党建工作的最大效能. 相似文献