微视野计检测中老年人正常眼黄斑区视网膜功能

目的 研究Microperimeter(MP)-1微视野计检测中老年人正常眼黄斑区视网膜光敏感度及固视率的正常值.方法 正常值测定.应用MP-1微视野计检测60名(60只眼)41～70岁健康受检者正常眼黄斑中心10°范围视网膜功能.根据受检者年龄分为3组,A组41～50岁,B组51～60岁,C组61～70岁.各年龄组间黄斑中心10°范围视网膜平均光敏感度和黄斑中心凹不同位置间平均光敏感度比较均采用秩和检验,前者以P＜0.017、后者以P＜0.025作为差异有统计学意义;受检者年龄与视网膜平均光敏感度的相关性采用相关分析法.结果 60只眼的黄斑中心10°范围内视网膜平均光敏感度为(19.7833±0.4906)dB,距黄斑中心5°、3°、1°环上的视网膜平均光敏感度分别为(19.5117±1.1044)、(19.8542±0.4099)及(19.9183±0.3895)dB.黄斑中心2°和4°范围内的平均固视率分别为(88.4667±9.9600)%和(97.2000±3.9091)%.距黄斑中心5°与3°环上的视网膜平均光敏感度比较,差异有统计学意义(Z=-2.943,P＜0.025);距黄斑中心3°与1°环上的视网膜平均光敏感度比较,差异有统计学意义(Z=-2.367,P＜0.025).结论 MP-1微视野计检查可用于评价黄斑区视网膜功能.3个年龄组间黄斑中心10°范围内视网膜平均光敏感度基本接近;距黄斑中心的距离不同,视网膜平均光敏感度不同;中老年人年龄与视网膜光敏感度不相关.

Abstract：

Objective To investigate the macular retinal sensitivity and fixation stability rates in normal subjects of middle and old age by using the MP-1 microperimeter. Methods This was a normal value test which enrolled 60 healthy subjects aging from 41 to 70 years old. It detected the retinal function of the central 10 degrees of the macular by using the MP-1 microperimeter. Sixty subjects were divided into three groups according to their ages: group A from 41 to 50, group B from 51 to 60 and group C from 61 to 70. Rank and testing methods were used to compare the mean retinal sensitivity (MS) within the central 10 degrees of the macular among the three groups, and P ＜0. 017 was used for statistical significance. Rank and testing methods were used to compare MS of different locations in the macular fovea, and P ＜ 0. 025 was used for statistical significance. Correlation analysis was used to analyze the correlation between the age and retinal MS values. Results The retinal MS within the central 10 degrees of the macular in 60 eyes of the 60 subjects was ( 19.7833 ± 0.4906) dB, and were ( 19.5117 ± 1. 1044), ( 19.8542 ± 0.4099) and ( 19. 9183 ±0. 3895) dB at 5 degrees, 3 degrees and 1 degree from the center of the macular, respectively.The mean fixation stability rates within 2 degrees and 4 degrees were (88. 4667 ±9. 9600)% and (97. 2000 ±3.9091 ) %, respectively. There was statistical significance between retinal MS at 5 degrees and at 3 degrees from the center of the macular ( Z = - 2. 943, P ＜ 0. 025 ); there was also statistical significance between retinal MS at 3 degrees and at 1 degree from the center of the macular ( Z = - 2. 367, P ＜ 0. 025 ).Conclusions MP-1 microperimetry examination could be used to evaluate the macular retinal function.There is no difference in the retinal MS within the central 10 degrees of the macular among the three groups of normal subjects of different ages. The retinal MS difference is statistically significant with different distances from the center of the macular; but there is no correlation between the age and the retinal sensitivities in normal subjects of middle and old age.     

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