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总结山东"三字经"小儿推拿流派、孙重三小儿推拿流派、张汉臣小儿推拿流派、金义成海派小儿推拿、刘开运小儿推拿流派和深圳岭南小儿推拿各自的手法特色,介绍各流派治疗小儿外感风寒发热的取穴和方法,指出不同流派小儿推拿手法治疗小儿外感风寒发热均有较好的临床疗效,但操作和选穴不尽相同,各有针对性、地域性及传承性。 相似文献
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目的 探讨妊娠期间甲状腺功能亢进对胎儿发育的影响。方法 选取2018年1月-2022年12月在医院住院分娩且妊娠期合并甲状腺功能亢进的新生儿72例作为甲亢组,另选取同期正常妊娠分娩的72例新生儿作对照组,观察两组新生儿体重、早产、足月小样儿(SGA)及胎儿窘迫发生率。结果 妊娠合并甲亢组新生儿低体重(LBW)、早产、胎儿窘迫发生率均高于健康对照组,出生体重明显低于对照组,差异均有统计学意义(P<0.05)。两组新生儿SGA发生率比较,差异无统计学意义(P>0.05)。结论 妊娠合并甲状腺功能亢进会导致LBW、早产、胎儿窘迫的发生,出生体重低于对照组,临床应及早发现、系统治疗,以改善妊娠合并甲状腺功能亢进新生儿结局。 相似文献
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Astrocytes play a major role in the reactive processes in response to neuronal injuries in the brain. Excessive gliosis is detrimental and can contribute to neuronal damage. CDS1 (TAPA), a member of the tetraspanin family of proteins, is upregulated by astrocytes after traumatic injury to the rat central nervous system (CNS). To further understand the role of CD81 in the inhibition of astrocytes, we analyzed the effects of a CD81 antibody, on cultured rat astrocytes. The results indicated that the effect worked in a dose-dependent manner with certain dosage range. It, however, reached a dosage equilibrium at a high dosage. Furthermore, anti-CD81 antibody remarkably inhibited the proliferation of astrocytes after incubation with astrocytes for different periods of time and the effect presented a time-dependent fashion. However, anti-CDS1 antibody substantially inhibited the proliferation of astrocytes at low density and middle density but slightly inhibited the proliferation of as- trocytes at high density, suggesting that the effect was positively correlated with the proliferative ability of astrocytes. Finally, the cell cycle of astrocytes exposured to anti-CD81 antibody was arrested in S phase at the initial stage and at G0/GI phase over time. These findings indicated that CD81 exert significant inhibitory effect, dose-dependently and time-dependently, on the proliferation of astrocytes and the effect is positively correlated with the proliferative capability of astrocytes. 相似文献
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小儿肺炎是儿科常见病, 又是威胁我国儿童健康的严重疾病,无论发病率还是病死率均居首位[1].由于本病严重威胁儿童健康成长, 世界卫生组织 ( WHO ) 将其列为 3 种重要的儿科疾病之一. 相似文献
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目的评价小剂量红霉素治疗新生儿胃食管反流病的疗效及安全性。方法检索并选取2000~2010年国内外公开发表的小剂量红霉素治疗新生儿胃食管反流病的随机对照临床试验文献,筛选符合纳入标准的文献进行研究。按照Jadad评价量表,对文献质量进行评价。由于对照疗法的不同,将纳入文献按对照疗法分类后进行meta分析。计算每种对照疗法的综合效应值。结果符合纳入标准的文献共20篇,对照组采用的疗法主要有三种:体位疗法(5篇),支持疗法(5篇),西咪替丁疗法(5篇)。其他疗法5篇,共纳入患者1201例,其中治疗组604例,对照组597例;患者的日龄均<28d;治疗组红霉素剂量范围为3~8mg/(kg?d)。小剂量红霉素与主要的三种对照疗法Meta分析结果:体位疗法OR=0.12(0.06~0.25);支持疗法0R=0.17,(0.07~0.39);西咪替丁疗法OR=0.41(0.24~0.70);表明小剂量红霉素的治疗效果优于其他疗法。另外,其不良事件的统计结果显示:发生率均<5‰(前胸部药疹3.3‰,大便次数增多3.3‰,腹泻1.7‰,代谢性酸中毒3.3‰),说明该疗法比较安全。结论小剂量红霉素治疗新生儿胃食管反流病有效,优于体位疗法、支持疗法,西咪替丁疗法,且不良事件发生率较低。 相似文献
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目的:研究miRNA-802(miR-802)及其靶基因ROS1在口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)中的表达及潜在临床意义。方法:收集原发OSCC组织及相应癌旁组织标本23例;荧光定量PCR检测各标本中miR-802及ROS1的表达;免疫组织化学检测各标本中ROS1的表达;结合患者临床病理资料,分析miR-802及ROS1在OSCC发生发展中可能的临床意义。结果:与癌旁组织相比较,OSCC组织中miR-802的表达显著降低(P<0.001),而ROS1的表达显著升高(P<0.01);相关性分析显示miR-802与ROS1在OSCC中的表达呈显著负相关(r=-0.746,P<0.0001);miR-802与ROS1的表达水平与患者年龄,性别、肿瘤大小等临床病理特征无显著相关性,而与TNM分期及淋巴结转移有显著相关性(P<0.05)。结论:miR-802通过介导其靶基因ROS1参与调控口腔鳞状癌的发生发展过程。 相似文献
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目的 探讨下颌骨边缘性切除术治疗涉及下颌骨的口腔鳞癌患者的临床疗效研究.方法 选取涉及下颌骨的口腔鳞癌患者64例,按手术方案不同分为观察组(n=32)和对照组(n=32),对照组予以下颌骨节段切除术,观察组予以下颌骨边缘性切除术.对比两组围术期情况、预后情况、术前、术后1个月Friction颞下颌关节功能紊乱指数(Fr... 相似文献
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中医对小儿多发性抽动症的认识进展 总被引:1,自引:0,他引:1
就中医对小儿多发性抽动症的病名、病因病机、辨证论治及综合治疗及调护等方面的研究和认识作了综述. 相似文献
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目的:观察葛根素注射液联合Epley 手法复位治疗后半规管良性阵发性位置性眩晕(PC-BPPV)的临床疗效,并分析其对PC-BPPV 患者眩晕残障程度评定量表(DHI) 评分的影响。方法:采用随机数字表法将80 例PC-BPPV 患者随机分为对照组与研究组各40 例。对照组采用Epley 手法复位治疗,研究组在此基础上联合葛根素注射液治疗,2 组均连续治疗2 周。比较2 组临床疗效及治疗前后中医证候积分、DHI 评分,并随访6 个月,比较2 组PC-BPPV 复发情况。结果:研究组治疗总有效率92.50%,高于对照组72.50%(P<0.05)。治疗前,2 组中医证候积分比较,差异无统计学意义(P>0.05);治疗1 周、2 周后,2 组中医证候积分逐渐降低(P<0.05),且研究组低于对照组(P<0.05)。治疗前,2 组DHI 评分比较,差异无统计学意义(P>0.05);治疗1 周、2 周后,2 组DHI 评分逐渐降低(P<0.05),且研究组低于对照组(P<0.05)。治疗后6 个月内,研究组复发率2.50%,低于对照组17.50% (P<0.05)。结论:葛根素注射液联合Epley 手法复位治疗PC-BPPV 疗效显著,可有效改善PC-BPPV 患者疾病症状,降低疾病复发率,可作为临床治疗PC-BPPV 的一种有效辅助手段。 相似文献
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Objective To assess the left ventricular contraction asynchrony in patients with acute myocardial infarction(AMI) by velocity vector imaging(VVI).Methods Sixty AMI patients and 40 healthy volunteers were included.Using VVI,the time to peak longitudinal systolic velocity (TL-V) was measured in the left ventricular long axis views,the time to peak radial systolic velocity (TR-V) was measured in parasternal short axis views.The deviation of the earliest and the latest TL-V and TR-V (Ts max-min) was measured,and the standard deviation of TL-V and TR-V (TS-SD) was also measured.Results ①TL-V ,TR-V of the infarcted and non-infarcted segments in patients with acute myocardial infarction were longer than those of the normal segments (P <0.05).②The longitudinal Tsmax-min,Ts-SD and the radial Tsmax-min,Ts-SD in infarcted patients were increased compared with the healthy volunteers (P <0.001).③Ts of the infarcted segments was increased in turn from the class Ⅰ to class Ⅳ of the cardiac function (P <0.001).Conclusions VVI could be used to assess the left ventricular contraction asynchrony in patients with AMI.VVI is a new useful method to determine the infarcted segments. 相似文献