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Pengpid Supa Peltzer Karl Puckpinyo Apa Chantarasongsuk Isareethika Jayasvasti 《International journal of diabetes in developing countries.》2019,39(1):123-131
International Journal of Diabetes in Developing Countries - Lifestyle intervention is recommended as the primary management for prehypertension and prediabetes. The aim of the study was to examine... 相似文献
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D. J. Weatherall J. B. Clegg Supa Na-Nakorn Prawase Wasi 《British journal of haematology》1969,16(3):251-268
The rate of globin chain production has been studied in patients with homozygous β-thalassaemia, heterozygous β-thalassaemia, haemoglobin E-thalassaemia, and sickle-cell-thalassaemia, and compared with that in non-thalassaemic individuals. A partial or total deficit of β-chain synthesis has been demonstrated in all forms of β-thalassaemia. This results in the production of a large intracellular pool of α-chains, the kinetics of which have been worked out. The α-chains in this pool appear to contain haem and are unstable, rapidly becoming associated with the stromal fraction. These findings are examined in terms of the pathogenesis of the anaemia of thalassaemia. 相似文献
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Thapinta D Jenkins RA Morgan PA Chiu J Boenim W Bussaratid V Chaddic C Naksrisook S Phonrat B Sirijongdee N Sornsathapornkul P Sontirat A Srisaengchai P Suwanarach C Wongkamhaeng S Brown AE Khamboonruang C Nitayaphan S Pitisuttithum P Thongchareon P;Thai AIDS Vaccine Evaluation Group 《Journal of acquired immune deficiency syndromes (1999)》2002,30(5):503-513
Factors believed to be predictive of retention through the recruitment and screening processes for preventive HIV trials were investigated in a large multisite phase I/II HIV vaccine trial in Thailand. Retention through recruitment was equal to or greater than in previous smaller trials with similar populations. The data suggested that recruitment proceeded in a stepwise manner with different influences at each step. Demographic and motivational variables were most important in predicting retention in making and keeping screening appointments. Altruistic or mixed altruistic and nonaltruistic motives were associated with greater retention. Laboratory/medical variables appeared to be the main influence on retention during screening, although some volunteers withdrew for different reasons. The frequent presence of mixed (altruistic and nonaltruistic) motives at initial contact suggests that motivation for trials is more complex than has been previously acknowledged. 相似文献
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Objective
The aim of this study was to assess the contributions of different forms of intimate partner violence (physical violence, sexual violence, psychological abuse, and stalking) on symptoms of posttraumatic stress disorder (PTSD) and depression.Methods
In all 268 women (18 years and older) consecutively receiving a protection order in the Vhembe district in South Africa were assessed by an external interviewer. Hierarchical regressions tested the unique effects of different types of intimate partner violence on PTSD and depression.Results
In terms of PTSD symptom severity, more than half (51.9%) of the sample reported severe PTSD and 66.4% reported severe depression symptoms. Two types of intimate partner violence (physical and sexual) were significantly associated with PTSD symptoms, while only psychological violence was moderately correlated with depression symptoms. Physical abuse contributed to the prediction of PTSD and psychological abuse to depression.Conclusions
A significant number of women with protection orders suffer from PTSD and depression. The results confirm a relationship between severity of intimate partner violence and mental health problems (PTSD and depression). Assessment of intimate partner violence should incorporate the multiple dimensions that have been identified as contributing to poor mental health. 相似文献10.
Michael Gurven Hillard Kaplan Alfredo Zelada Supa 《American journal of human biology》2007,19(3):376-398
This paper examines regional and temporal trends in mortality patterns among the Tsimane, a population of small-scale forager-horticulturalists in lowland Bolivia. We compare age-specific mortality in remote forest and riverine regions with that in more acculturated villages and examine mortality changes among all age groups over the past 50 years. Discrete-time logistic regression is used to examine impacts of region, period, sex, and age on mortality hazard. Villages in the remote forest and riverine regions show 2-4 times higher mortality rates from infancy until middle adulthood than in the acculturated region. While there was little change in mortality for most of the life course over the period 1950-1989, overall life expectancy at birth improved by 10 years from 45 to 53 after 1990. In both periods, over half of all deaths were due to infectious disease, especially respiratory and gastrointestinal infections. Accidents and violence accounted for a quarter of all deaths. Unlike typical patterns described by epidemiologic transition theory, we find a much larger period reduction of death rates during middle and late adulthood than during infancy or childhood. In the remote villages, infant death rates changed little, whereas death rates among older adults decreased sharply. We hypothesize that this pattern is due to a combination of differential access to medical interventions, a continued lack of public health infrastructure and Tsimane cultural beliefs concerning sickness and dying. 相似文献