全文获取类型
收费全文 | 734篇 |
免费 | 22篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 23篇 |
妇产科学 | 15篇 |
基础医学 | 51篇 |
口腔科学 | 6篇 |
临床医学 | 64篇 |
内科学 | 166篇 |
皮肤病学 | 30篇 |
神经病学 | 24篇 |
特种医学 | 93篇 |
外科学 | 95篇 |
综合类 | 52篇 |
预防医学 | 32篇 |
眼科学 | 15篇 |
药学 | 45篇 |
中国医学 | 5篇 |
肿瘤学 | 37篇 |
出版年
2015年 | 4篇 |
2014年 | 7篇 |
2013年 | 14篇 |
2012年 | 11篇 |
2011年 | 16篇 |
2010年 | 18篇 |
2009年 | 24篇 |
2008年 | 15篇 |
2007年 | 6篇 |
2006年 | 7篇 |
2003年 | 4篇 |
2002年 | 5篇 |
2001年 | 6篇 |
1999年 | 7篇 |
1998年 | 19篇 |
1997年 | 30篇 |
1996年 | 30篇 |
1995年 | 26篇 |
1994年 | 18篇 |
1993年 | 18篇 |
1992年 | 9篇 |
1991年 | 5篇 |
1990年 | 12篇 |
1989年 | 19篇 |
1988年 | 25篇 |
1987年 | 18篇 |
1986年 | 17篇 |
1985年 | 19篇 |
1984年 | 7篇 |
1983年 | 10篇 |
1982年 | 13篇 |
1981年 | 8篇 |
1980年 | 6篇 |
1979年 | 8篇 |
1978年 | 7篇 |
1977年 | 15篇 |
1976年 | 9篇 |
1975年 | 8篇 |
1973年 | 6篇 |
1968年 | 3篇 |
1963年 | 10篇 |
1962年 | 3篇 |
1959年 | 16篇 |
1958年 | 38篇 |
1957年 | 31篇 |
1956年 | 22篇 |
1955年 | 24篇 |
1954年 | 38篇 |
1949年 | 16篇 |
1948年 | 15篇 |
排序方式: 共有760条查询结果,搜索用时 15 毫秒
1.
N.B.SIMPSON 《The British journal of dermatology》1987,117(1):43-47
Sebum excretion rate was measured by a photometric technique. We demonstrated a high correlation between sebum excretion rates on the left and right sides of the upper back and between back and forehead skin. Sebum excretion rate measurements overlying an open comedone (blackhead) were significantly lower than those obtained from normal skin. This observation demonstrates a functional obstruction to the outflow of sebum and would suggest that the lack of involvement of open comedones in inflammatory acne is not because of the maintenance of a free flow of sebum. 相似文献
2.
Leonidas JC; Berdon WE; Valderrama E; Neveling U; Schuval S; Weiss SJ; Hilfer C; Godine L 《Radiology》1996,198(2):377
3.
COMPARISON OF THE EFFECTS OF ATROPINE AND GLYCOPYRROLATE ON COGNITIVE FUNCTION FOLLOWING GENERAL ANAESTHESIA 总被引:2,自引:1,他引:1
Tests of orientation, concentration and shortterm visual memorywere used to assess 72 patients 1 day before, and 2 days after,elective major surgery. Patients were premedicated with papaveretumand either atropine or glycopyrrolate, before receiving a standardgeneral anaesthetic. Those who had received atropine showedsignificant postoperative short-term memory deficit (P< 0.01),but no change in orientation or concentration. Those who hadbeen given glycopyrrolate showed no significant cognitive changesafter surgery. As glycopyrrolate does not cross the blood-brainbarrier freely, these findings support the involvement of centralcholinergic mechanisms in the deterioration of cognitive functionin the postoperative period. 相似文献
4.
5.
6.
Normal and diseased isolated lungs: high-resolution CT 总被引:8,自引:0,他引:8
7.
8.
9.
Coakley G; Mok CC; Hajeer AH; Ollier WE; Turner D; Sinnott PJ; Hutchinson IV; Panayi GS; Lanchbury JS 《Rheumatology (Oxford, England)》1998,37(9):988-991
OBJECTIVE: To examine whether promoter polymorphisms associated with
variation in interleukin-10 (IL-10) production are relevant to the
development of rheumatoid arthritis (RA) or Felty's syndrome (FS). METHODS:
DNA was obtained from 44 FS patients, 117 RA patients and 295 controls. The
promoter region between -533 and - 1120 was amplified by polymerase chain
reaction, and polymorphisms detected by restriction enzyme digest or
sequence-specific oligonucleotide probing. RESULTS: We found no significant
difference in allele or haplotype frequencies between the groups.
CONCLUSION: There is no association between FS or RA and these recently
identified IL-10 promoter polymorphisms. Other genetic or environmental
factors could explain the alterations in IL-10 levels seen in these
conditions.
相似文献
10.
Ether lipids (EL) and hyperthermia have been shown to possess a relatively selective cytotoxicity to leukemic cells. In this study, the combined effects of EL (ET-18-OCH3, ET-16-NHCOCH3, or BM 41.440) and hyperthermia on the growth of hematopoietic progenitors, myeloid leukemic cell lines, and leukemic cells obtained from patients with acute myeloid leukemia (AML) were examined to determine if this combination resulted in a greater selective killing of leukemic cells than that achieved by either EL or heat alone. When the cells were treated simultaneously with EL (50 micrograms/mL) and hyperthermia (42 degrees C) for one hour, the killing of leukemic cell line cells was enhanced considerably. Among the three EL, however, the combination of ET-18-OCH3 and heat seemed to be the most cytotoxic to leukemic cell line cells with no effect on the growth of hematopoietic progenitors. An increase in the duration of treatment with ET-18-OCH3 to four hours with heat added during the last hour resulted in a further reduction of leukemic cell line cells while sparing 50% of hematopoietic progenitors after cryopreservation. The combined treatment with ET-18-OCH3 and heat also inhibited the growth of leukemic progenitors obtained from AML patients by 97% to 100%. These data indicate that the combined treatment with EL and hyperthermia might offer an efficient means to eliminate myeloid leukemic cells in vitro. 相似文献