0．1％他克莫司治疗浆细胞性龟头炎

背景：浆细胞性龟头炎或Zoon龟头炎（BZ）是成年男性的一种常见疾病，皮肤损害多位于龟头，也可累及包皮，其病因尚不明确。目的：报道采用0．1％他克莫司软膏治疗两例BZ患者的经验，并与其他局部疗法对比。患者和方法：两例未曾行包皮环切术的高加索成年男性均患BZ，局部外用0．1％他克莫司软膏，2次／d。结果：分别随访1年和10个月，发现两例患者的皮肤损害均显著改善。结论：局部外用0．1％他克莫司软膏治疗BZ安全有效。     

Plasma cell balanitis treated with tacrolimus 0.1%

BACKGROUND: Plasma cell balanitis or balanitis of Zoon (BZ) is a frequent diagnosis in mature men and lesions are generally localized on the glans but may involve the prepuce; its aetiology remains unknown. OBJECTIVES: To present our experience with tacrolimus 0.1% ointment in the treatment of two patients with BZ refractive to other topical treatments. PATIENTS AND METHODS: Two uncircumcised mature caucasian males were seen, both presenting with BZ; topical tacrolimus 0.1% ointment twice daily was prescribed in each case. RESULTS: Marked improvement of the lesions in both patients has been observed, with follow-up of 1 year and 10 months, respectively. CONCLUSIONS: Topical tacrolimus 0.1% ointment is an effective and safe treatment for BZ.