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Treaba D Assad L Govil H Sariya D Reddy VB Kluskens L Green L Selvaggi SM Gattuso P 《Diagnostic cytopathology》2002,26(6):380-383
At the present time fine-needle aspiration (FNA) is considered a routine diagnostic procedure in evaluating neoplastic vs. nonneoplastic lesions in many organs, with high sensitivity and specificity. The purpose of this study was to assess the utility of FNA in areas of diagnostic difficulty and its limitations in evaluating bone lesions in patients with a previous history of malignancy. From 1989 to 2000, 249 CT-guided FNAs of bone lesion were performed at our institutions; 187/249 (75.1%) patients had a previous history of malignancy. Aspirated material was air-dried for Diff-Quik stain or fixed in ethanol for Papanicolaou staining. Subsequent surgical tissue was available in 69/187 (36.9%) of the cases. There were 114 males and 73 females, ages 14-86 yr (mean, 64 yr). The primary tumor site was lung 49, genitourinary 46, breast 31, gastrointestinal 28, hematopoietic 26, soft tissue/skin 5, and thyroid 2. There were 125 FNAs of the vertebral spine, 19 from the pelvis, 11 from the ribs, 9 from the sternum, 5 from the femur, and 18 from miscellaneous bone sites. Out of 187, 166 (88.7%) were malignant aspirates confirming the patients' primary malignancies. The most common malignancy encountered was adenocarcinoma, 126/187 (67.4%). Surgical tissue was available for review in 69 patients and the results were in agreement with the FNAs diagnosis in all cases. Nine out of 187 (4.8%) cases were diagnosed as marrow elements on cytological material. These patients have been followed for 1-9 yr and have failed to reveal signs or symptoms of clinical recurrence. Three out of 187 (1.6%) cases showed osteomyelitis. Nine out of 187 (4.8%) were unsatisfactory specimens, with biopsy follow-up available in four cases, showing three metastatic tumors and one case of osteomyelitis. FNA of metastatic bone lesions is a major step in pretreatment diagnosis. On satisfactory specimens, the cytological diagnosis viewed in the clinical-radiological context proves to be similar to surgical diagnosis. FNA is an excellent technique with a high accuracy rate in assessing metastatic bone lesions. 相似文献
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Summary. A virus isolate causing mosaic disease of commercial sugarcane was purified to homogeneity. Electron microscopy revealed
flexuous filamentous virus particles of ca 890 × 15 nm. The virus isolate reacted positively with heterologous antiserum to
narcissus latent virus form UK, but failed to react with potyvirus group specific antiserum. N-terminal sequencing of the
intact coat protein (CP) and the tryptic peptides indicated that the virus was probably a potyvirus but distinct from several
reported potyviruses. Comparison of the 3′-terminal 1084 nucleotide sequence of the RNA genome of this virus revealed 93.6%
sequence identity in the coat protein coding region with the recently described sugarcane streak mosaic virus (Pakistani isolate).
The molecular weight of the coat protein (40 kDa) was higher than that deduced from the amino acid sequence (34 kDa). The
apparent increase in size was shown to be due to glycosylation of the coat protein which has not been reported thus far in
the family, Potyviridae. This is the first report on the molecular characterization of a virus causing mosaic disease of sugarcane in India and the
results demonstrate that the virus is a strain of sugarcane streak mosaic virus, a member of the Tritimovirus genus of the Potyviridae. We have named it sugarcane streak mosaic virus – Andhra Pradesh isolate (SCSMV-AP).
Received October 14, 1997 Accepted August 7, 1998 相似文献
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Capillaria hepatica parasitism 总被引:1,自引:0,他引:1
Capillaria hepatica is rarely encountered in humans, with fewer than 30 documented cases. The clinico-pathological features
of capillaria hepatica infection, diagnosed on liver biopsy of a 6-year-old child are discussed. Pathologically, it is characterised
by prominent granulomatous lesions in the liver surrounding the eggs, which on cursory examination may be confused withSchistosoma mansoni. 相似文献
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Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer 下载免费PDF全文
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Hema Mittal Sunita Rai Dheeraj Shah S. V. Madhu Gopesh Mehrotra Rajeev Kumar Malhotra Piyush Gupta 《Indian pediatrics》2014,51(4):265-272