全文获取类型
收费全文 | 1408篇 |
免费 | 79篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 55篇 |
妇产科学 | 20篇 |
基础医学 | 138篇 |
口腔科学 | 47篇 |
临床医学 | 194篇 |
内科学 | 244篇 |
皮肤病学 | 35篇 |
神经病学 | 46篇 |
特种医学 | 190篇 |
外科学 | 264篇 |
综合类 | 22篇 |
预防医学 | 98篇 |
眼科学 | 18篇 |
药学 | 68篇 |
中国医学 | 1篇 |
肿瘤学 | 51篇 |
出版年
2021年 | 26篇 |
2020年 | 21篇 |
2019年 | 25篇 |
2018年 | 31篇 |
2017年 | 23篇 |
2016年 | 16篇 |
2015年 | 27篇 |
2014年 | 42篇 |
2013年 | 49篇 |
2012年 | 49篇 |
2011年 | 40篇 |
2010年 | 40篇 |
2009年 | 42篇 |
2008年 | 46篇 |
2007年 | 44篇 |
2006年 | 28篇 |
2005年 | 27篇 |
2004年 | 35篇 |
2003年 | 33篇 |
2002年 | 18篇 |
2001年 | 25篇 |
2000年 | 30篇 |
1999年 | 31篇 |
1998年 | 27篇 |
1997年 | 41篇 |
1996年 | 50篇 |
1995年 | 31篇 |
1994年 | 25篇 |
1993年 | 37篇 |
1992年 | 16篇 |
1991年 | 17篇 |
1990年 | 20篇 |
1989年 | 24篇 |
1988年 | 25篇 |
1987年 | 42篇 |
1986年 | 40篇 |
1985年 | 25篇 |
1984年 | 17篇 |
1983年 | 12篇 |
1982年 | 26篇 |
1979年 | 14篇 |
1977年 | 17篇 |
1976年 | 18篇 |
1973年 | 13篇 |
1972年 | 11篇 |
1971年 | 12篇 |
1969年 | 15篇 |
1942年 | 12篇 |
1941年 | 11篇 |
1934年 | 11篇 |
排序方式: 共有1495条查询结果,搜索用时 15 毫秒
1.
2.
D Gröne† R Treudler† EM de Villiers‡ R Husak† CE Orfanos† ChC Zouboulis†§ 《Journal of the European Academy of Dermatology and Venereology》2006,20(2):202-205
Cidofovir is an acyclic nucleoside phosphonate with broad-spectrum activity against DNA viruses, including human papilloma virus (HPV). However, data on the efficacy of cidofovir in an immunosuppressive setting remain contradictory. We report for the first time on the promotion of the healing of recalcitrant warts in a patient with myelodysplastic syndrome with intravenous cidofovir treatment. 相似文献
3.
Lack of effect of aspartame or of L-phenylalanine on photically induced myoclonus in the baboon, Papio papio 总被引:1,自引:0,他引:1
The effects of large doses of L-phenylalanine and of aspartame on seizure susceptibility and severity have been assessed in baboons Papio papio from Senegal which show photosensitive epileptic responses similar to primary generalised epilepsy in man. L-Phenylalanine, 50, 150 or 450 mg/kg, or aspartame, 300 or 1000 mg/kg, were administered orally. Peak plasma L-phenylalanine concentrations of approximately 2000 mumoles/l occurred 1-4 h after the highest dose of L-phenylalanine or aspartame. The plasma L-phenylalanine to large neutral amino acid ratio increased approximately 30-fold at this time. Compared with water administration there were no changes in epileptic responses 1-5 h after either treatment. In this primate model of epilepsy acute increases in plasma phenylalanine concentration are neither pro- nor anticonvulsant. 相似文献
4.
5.
Persephone Borrow Jennifer L. Cornell Mary D. Ruppe Lennart Mucke 《Journal of neuroimmunology》1995,61(2)
Transgenic mice expressing a defined microbial antigen from central nervous system (CNS) cell type-specific promoters can be utilized to investigate the consequences of induction of peripheral immune responses to foreign antigens produced by different CNS cell types. Immunization of mice expressing β-galactosidase (β-gal) in astrocytes with this protein resulted in antigen-dependent infiltration of the CNS by mononuclear cells, principally CD4+ T lymphocytes and monocyte/macrophages. The perivascular and intraparenchymal infiltrates, which were located predominantly in the hippocampal formation and cerebellum, the areas of highest β-gal expression, were associated with astrocytosis, microgliosis, and a generalized increase in blood-brain barrier permeability. The resemblance of these pathological changes to aspects of human immune inflammatory CNS disorders e.g. multiple sclerosis, suggests that an initiating step in the process by which such complex diseases are produced could be the induction of peripheral immune responses to antigens expressed in astrocytes. 相似文献
6.
Management of fractures in patients with osteoporosis 总被引:4,自引:0,他引:4
C N Cornell 《The Orthopedic clinics of North America》1990,21(1):125-141
The treatment of the most common osteoporotic fractures has been reviewed. In general, early functional treatment is used to allow early restoration of function and weight bearing. Fracture treatment should always be accompanied by an investigation of the bone mass in these patients. Nutritional support and calcium and vitamin supplementation should be provided during the healing phase. 相似文献
7.
8.
9.
Digital radiography of subtle pulmonary abnormalities: an ROC study of the effect of pixel size on observer performance 总被引:3,自引:0,他引:3
Forty conventional radiographs with examples of mild interstitial infiltrates and subtle pneumothoraces and 40 normal studies of the chest were selected and digitized, with pixel sizes of 1.0, 0.5, 0.2, and 0.1 mm. Observer performance tests were carried out using receiver operating characteristic analysis. Conventional radiographs and digitized images were compared. The results indicate that, in such cases, diagnostic accuracy increases significantly as the pixel size is reduced, at least to the 0.1-mm level. We conclude that, for digital systems using screen-film or similar image receptors, use of a pixel size substantially larger than 0.1 mm may result in some loss of diagnostic accuracy. 相似文献