宫颈上皮内瘤变72例临床及病理分析

目的探讨宫颈上皮内瘤变（CIN）的临床及病理特征,为CIN防治提供依据。方法对59医院和478医院病理诊断CIN的72例患者的临床及病理资料进行回顾性分析。结果CINI29例,CINⅡ23例,CINⅢ20例,平均年龄38．3岁,≤35岁30例（42％）。其中31例进行人乳头状病毒（HPV）检测,阳性率71％（22／31）。结论阴道镜下多点活检可以提高诊断准确性,准确的病理诊断有利于选择恰当的治疗方法,对防止过度治疗和治疗不足有重要意义。     

呼吸道支原体感染的临床分析

肺炎支原体（Mycoplasmal）是导致呼吸道感染的常见病原体之一,目前国内外相关报道均显示近年来呼吸道肺炎支原体感染的发病率有明显增高的趋势,自2004年至2005年来我科治疗呼吸道支原体感染患者160例报告如下。     

二甲双胍治疗多囊卵巢综合征临床疗效分析

二甲双胍治疗PCOS有一定效果，副反应小，体外研究无致畸作用。对有Ins特别是伴有肥胖的PCOS患者，可选择使用或与促排卵药物联合应用，近期可促使排卵及妊娠，而远期效果是改善糖，脂代谢紊乱，预防或减少糖尿病及心血管的发生。     

基于有限元法分析钝力性脾损伤的机制

Objective To explore the biomechanical mechanism of blunt spleen injury based on finite element analysis. Methods A fist finite element model was used to simulate the impact at 4-8 m/s in the spleen area of THUMS4.0 human body model from the front of the left costal area, the left anterior axillary line and the rear scapular line. The strain distribution and damage of the spleen under different conditions were observed. The simulation results were compared with the clinical cases of spleen rupture to analyze the mechanism of spleen injury. Results The damage location and strain distribution of the spleen could vary under different conditions. Due to the special anatomical location of the spleen, a blunt impact at the speed of 4-8 m/s on the front side did not easily cause spleen injury, and the strain was distributed mainly in the front of the spleen and the spleen hilum; a similar blunt impact on the left side was likely to cause spleen diaphragmatic surface injury, the splenic visceral surface could be injured by the compression of the medial tissue and organs and the traction of the splenic pedicle, and the strain was distributed in the spleen diaphragmatic and visceral surfaces; an impact on the back side was likely to cause injuries in the posterior portion and hilum of the spleen, and the strain was mainly concentrated in the injured area. Conclusion Blunt spleen injuries caused by punches on the abdomen are mostly caused by direct impact on the ribs, the compression by the surrounding tissues and organs and the traction by the spleen pedicle.