超声引导单纯性肾囊肿的穿刺硬化剂治疗

目的探讨超声引导肾囊肿的穿刺硬化剂治疗的临床疗效。方法本组122例患者、肾囊肿126个（左肾68个、右肾58个），均经超声引导下穿刺硬化剂的治疗。结果本组126个囊肿，术后囊肿消失一般需时1～3mo，6mo内消失占多数，少数需要时间较长些，治愈率92．06％，有效率100％，囊肿消失后未见1例复发者。结论肾囊肿是一种常见的良性疾病，较大时可引起一系列不良后果，外科开放性手术摘除其创伤较大、愈合较慢、花费较多而超声引导穿刺硬化剂治疗简单、安全、方便且疗效满意，现已成为肾囊肿的一种常规治疗方法。     

腹腔内疝的CT表现

腹腔内脏器穿过腹膜或膜突入另一腹腔内间隙称为腹腔内疝（internal abdominal hernias）。最常表现为一段小肠嵌入正常或异常的腹腔内孔道，引起急性小肠梗阻。作为疝口的结构可以是腹腔内的正常解剖结构，如裂孔、隐窝、陷窝等，     

X-感光胶片图像数字化处理系统

为使某些具有教学意义或需长期保存的胶片图像能用计算机储存,病人摄片后能拥有一份满意的打印图像,临床医师能随时与影像科进行电脑上阅片会诊,我们研制了胶片图像数安化处理系统.     

Effect of [-Ca^2＋]i and Neuronal Mitochondria Transmembrane Potentials in Hippocampus of Murine Cytomegalovirus Infected Mice

According to a study launched by WHO in1996 ,the anomaly in the central nervous system(CNS) accounted for 17 % of all congenital mal-formations , while human cytomegalovirus ( HC-MV) acted as one of the major pathogens of con-genital anomalies in human beings . The most seri-ous consequences following HCMV infection in-clude hydrocephalus , rachischisis , microcephaly ,cerebral calcification, sensorineural hearing lossand paralysis , etc . CMV is a neurotrophic virusand the infection in …     

胰源性区域性门静脉高压的螺旋CT表现及临床意义

胰腺肿瘤或炎性病变易侵犯或压迫脾静脉而致其阻塞,造成其引流区域血管系统形态和功能上的改变,称为胰源性区域性门静脉高压症(PSPH).①胃短静脉→胃底静脉丛→胃冠状静脉和②胃网膜静脉→胃结肠干→肠系膜上静脉是PSPH主要的两个侧支循环通道,在螺旋CT上表现出特征性的分布和走行,并在胰腺癌术前分期和评估PSPH方面具有重要临床意义.增强多排螺旋CT血管成像技术有利于连续追踪上述血管走行, 清晰显示其毗邻关系,有助于PSPH的诊断.     

加味茵陈蒿汤对UDCA应答不佳的原发性胆汁性胆管炎患者肝纤维化的影响

目的:观察加味茵陈蒿汤对熊去氧胆酸(UDCA)应答不佳的原发性胆汁性胆管炎(PBC)患者肝纤维化指标及血清转化生长因子β1(TGF-β1)、Smad3水平的影响.方法:纳入61例UDCA应答不佳的PBC患者,随机分为治疗组30例和对照组31例.两组患者均给予足量UDCA治疗,治疗组患者在此基础上加用加味茵陈蒿汤口服,两...     

曲前列尼尔在成人先天性心脏病合并肺动脉高压围术期的疗效

目的 观察围术期应用曲前列尼尔对成人先天性心脏病合并中、重度肺动脉高压的疗效.方法 成人先天性心脏病患者21例,术前心脏超声检查及右心导管造影确诊为中、重度肺动脉高压,均行一期心内畸形矫治术.所有患者术中放置Swan-Ganz导管.心肺转流停机前即开始持续泵入曲前列尼尔,记录用药前、用药后4 h、12 h、24 h及停...     

儿童腹膜后肾周间隙肾脏肿瘤与肾周肿瘤的多层螺旋CT对照研究

目的 探讨儿童腹膜后肾周间隙肾脏与肾周起源肿瘤的主要CT征象及鉴别诊断.方法 收集经手术病理证实的儿童腹膜后肾周间隙肿瘤40例,以病理结果为依据,将其分为肾脏肿瘤组(n=14)和肾周肿瘤组(n=26),并对其CT表现及相关临床资料进行了对照分析.结果 肾脏肿瘤组的定位及起源征象以"新月征"、"鸟嘴征"、"肾脏嵌入征"、"肿瘤供血动脉征"多见,而肾周肿瘤组以肾脏移位伴肾轴旋转、肿瘤中心层面位于肾轮廓外多见.肾脏肿瘤组肿瘤的主要CT征象以"假包膜"、"囊变、坏死"、肿瘤血管丰富、下腔静脉内瘤栓及远处转移多见,而肾周肿瘤组以"分叶征"、"瘤内钙化"多见.结论 多排螺旋CT增强扫描可用于儿童腹膜后肿瘤的位置、起源及肿瘤的组织学特征的观察,其相应的CT征象有助于儿童腹膜后肾周间隙肾脏与肾周起源肿瘤的鉴别.     

Screening Amblyopia for Year 1 Students with Uncorrected Vision and Stereopsis Test in Central China

Background: Screening for amblyopia at earliest is important for early treatment and better prognosis. This study aimed at evaluating the validity of uncorrected distant and near visual acuity and stereoacuity for screening amblyopia in year 1 students in central China. Methods: By stratified cluster sampling, 3112 year 1 students from 11 Anyang primary schools were selected for the study. All the participants underwent uncorrected distant and near visual acuity, stereopsis test, cycloplegic refraction, best corrected visual acuity (BCVA), cover test and ocular movement examination. Visual acuity (VA) was measured with a logarithm of the minimum angle of resolution (logMAR) chart. Stereoacuity was measured with the Lang II stereo card and TNO test. Amblyopia was defined as the BCVA less than or equal to 0.1 logMAR units of any eye in the absence of significant pathological abnormalities. The sensitivity, specificity, positive predictive value and negative predictive value of uncorrected visual acuity and stereoacuity for amblyopia were analyzed. Results: Out of the 3112 eligible students, 2893 (92.96%) students completed the examinations. The average age of the students was 7.10±0.41 （mean ± standard deviation, SD）years. Screened by distant visual acuity with low cutoff (logMAR0.1), high cutoff (logMAR0.0) and near visual acuity (logMAR0.0), 31.64, 73.18 and 50.23% students were abnormal. Screened by stereopsis test, only 4.69% students were abnormal. By a senior pediatric ophthalmologist, 61 students were diagnosed amblyopia. The sensitivities of distant visual acuity with low/high cutoff and near visual acuity were 92.31/100.00 and 80.77%, whereas that of stereoacuity by TNO test was 15.38%. Simultaneous testing of either two of the three tests improved the sensitivity. Conclusions: Distant visual acuity test of high cutoff alone display a high sensitivity but a low specificity. Simultaneous testing of distant visual acuity of low cutoff and stereoacuity is a better choice to balance between sensitivity and specificity.     

腺病毒介导的ING4基因对SMMC-7721人肝癌细胞生长的抑制效应

目的研究腺病毒介导的ING4（Ad-ING4）基因对体外SMMC-7721人肝癌细胞的生长抑制作用。方法将腺病毒空载体Ad-GFP及重组腺病毒Ad-ING4分别感染SMMC-7721细胞,采用RT-PCR法及间接免疫荧光检测ING4基因的转录和表达;荧光显微镜观察Ad-ING4对SMMC-7721细胞的细胞毒作用;MTT比色法绘制细胞生长曲线,计算生长抑制率;流式细胞术（FCM）检测Ad-ING4对细胞凋亡的影响;DAPI核荧光染色检测细胞凋亡的核形态学变化。结果 RT-PCR及间接免疫荧光显示Ad-ING4能在SMMC-7721细胞内稳定表达;Ad-ING4感染72h和96h后对细胞的生长抑制率达33.82%和50.70%;FCM检测有明显的凋亡峰,凋亡率可达46.7%;DAPI染色结果显示SMMC-7721细胞胞核呈现核深染、固缩、断裂等细胞核凋亡的形态改变。结论 Ad-ING4能够明显抑制SMMC-7721细胞的增殖,并诱导其凋亡。