排序方式: 共有11条查询结果,搜索用时 31 毫秒
1.
静脉给予纳洛酮2mg/kg期间可使内毒素休克狗的平均动脉压(MAP)、左心室收缩压(LVSP)及其一阶导数(±dp/dt max)和心力环面积(CFU)增加,但对肾血流量(RBF)、尿量及20h的存活率无明显影响。将本实验结果与山莨菪碱、躯体刺激效应进行比较,表明三者中山莨菪碱对休克动物的循环改善作用最明显。 相似文献
2.
Yao Tai姚泰 Xiao Yong-fu肖永福 Sun Xiang-ying孙祥莺 Tong Hua-hua童华华 Yuan Man袁曼 Xu Zhao-yue徐肇弱 Dai Zi-ying戴自英Shanghai First Medical. Col.lege Slzanghai 《中华医学杂志(英文版)》1984,97(12):871-876
Experiments were carried out in mongrel dogs
anesthetized with pentobarbital. Escherichia coli
endotoxin (5 mg/kg, iv) was given to produce circula-
tory shock. In 6 dogs, 5 mg/kg of anisodamine was
infused intravenously for 60 minutes causing an in-
crease in heart rate, left ventricular systolic pressure,
positive and negative maximum dp/dt and mean
arterial pressure. Renal vascular resistance was
decreased, while renal blood flow and urinary out
flow increased. No such changes were observed in
6 control animals which were given saline infusion.
The results obtained indicate that anisodamine given
at early stage of endotoxin shock improves myocardial
contractility. 相似文献
3.
我们对清醒犬的实验表明:电针既能使急性实验性高血压降压,又能使急性实验性低血压升压,前者与电针时内源性鸦片样物质的释放和中枢内鸦片样受体的激活有关,而后者与电针时中枢内胆硷能系统活动增强有联系。本工作试图观察不同血压水平下不同参数的腓深神经刺激对肾神经活动的影响,并进一步分析其机理。 相似文献
4.
胡旭初等报道用静脉注射药物造成动物血压异常,针刺可使血压异常状态趋于正常化。我们证实针刺对清醒犬静脉匀速注射去甲肾上腺素造成的实验性高血压有显著的降压效应,此降压效应与电针时内源性鸦片样物质的释放和神经中枢内鸦片样受体的激活有关。本工作试图观察针刺对急性实验性低血压有无升压作用,并分析其机制。 相似文献
5.
6.
目的分析四川省藏区若尔盖县及其不同区的肺结核病人发现水平,并讨论影响病人发现的相关因素.方法利用初诊病人登记表和初诊病人问卷调查表,对获取的信息运用聚类分析、方差分析和X2检验等统计学方法进行分析.结果2003年7月7日至2004年7月6日若尔盖县结核病初诊病人就诊率7.10‰.,肺结核病登记率220.7/10万,以县城为中心的区(多玛区)和半农半牧区(铁布区、巴西区)的病人发现水平高于牧区(唐克区、纳摩区).铁布区和多玛区初诊病人的首诊医生为结防医生的比例高于其他区,分别为16.7%和22.6%,并且铁布区的初诊病人对结核病的了解情况好于其他各区.结论政府重视、广泛的健康教育和提高卫生服务的地理可及性是提高结核病人发现水平的关键. 相似文献
7.
Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels in the heart modulate cardiac automaticity via the hyperpolarization-activated cation current (named If, Ih, or Iq ). Recent studies have unveiled the molecular identity of HCN (HCN1-4) channels. HCN isoforms are unevenly expressed in the heart, even in the sinoatrial node. Features of HCN currents have been characterized in cardiac and other types of cells or in cell lines transfected with the HCN isoforms. The factors modulating Ih and the physiological significance of HCN channels in the heart have been extensively investigated in recent years. The hypothesis for transplanting and/or creating biological pacemakers to replace diseased sinoatrial and/or atrioventricular nodes has been postulated and tested in animal models. Local overexpression of HCN2 channels in the left atrium or in the left conductive bundle branch of the left ventricle via gene delivery induced significant Ih and escape rhythms during vagal stimulation in canines. In addition, implantation of human mesenchymal stem cells with overexpression of HCN2 channels to the canine left ventricular wall was associated with formation of spontaneous escape rhythms of left-sided origin during vagal-stimulation-induced sinus arrest. This preliminary data suggest that the use of HCN channels may hold great promise in the development of biological pacemakers. 相似文献
8.
西乡县位于陕西省南部,北纬32°31-33°14,年均气温14.1℃,相对湿度85%,年降雨量1077mm。高川区辖3个乡,共45433人。川河纵贯全区,群众多居住在河岸两侧。水田占耕地面积的14,主产玉米、水稻。群众夏季很少露宿,蚊帐使用率由以... 相似文献
9.
目的:了解四川藏区疑似结核病人的相关社会经济学特征。方法:采用调查表进行面对面调查,对获得的相关信息进行描述性分析。结果:共调查160例结核病疑似病人,藏族占95.6%。2003年68.1%的疑似病人家庭人均现金收入低于当地农村居民当年人均纯收入,43.8%的疑似病人家庭医药费用支出超过当年家庭总收入的50%。76.9%的疑似病人在此次患病前不了解任何关于结核病症状的知识,52.5%不知道县里进行结核病诊断治疗的机构。疑似病人就诊延迟比例为52.5%,就诊延迟时间中位数为47d。结核病疑似病人寻求结核病卫生服务过程中的困难主要有:经济困难;语言不通;不知道看病的地点;交通不便等。结论:应大力发展农牧区经济,建立农民医疗保障体系,普及结核病防治知识。 相似文献
10.