实践教学量化管理体系在临床教学中的应用

本文介绍了量化管理模式的主要内容、人员组成、具体实施及临床实习成绩考核情况,并讨论了临床医学人才应当具备的基本素质、实践教学量化管理体系建立的意义.实践证明,按照该体系要求进行实习和考评的学生优良率明显提高.评估体系考核内容全面,标准具体,指标量化,操作性强,有利于提高学生的临床技能,是一种提高教学质量的有效方法.     

产前经腹联合经阴道超声诊断前置胎盘并胎盘植入

目的观察产前经腹联合经阴道超声检查对前置胎盘并胎盘植入的诊断效能。方法回顾性分76例前置胎盘并胎盘植入孕妇产前超声资料,其中39例接受单纯经腹超声检查(经腹检查组)、37例接受经腹联合经阴道超声检查(联合检查组);比较2组诊断胎盘植入准确率,分析联合检查组胎盘植入分型准确率。结果联合检查组产前诊断胎盘植入准确率91.89%(34/37),高于经腹超声检查组[30.77%(12/39),P<0.001]。依据临床分娩所见或分娩后组织病理学结果,联合检查组粘连型胎盘植入0例、植入型6例、穿透型31例;产前超声正确诊断粘连型0例、植入型4例、穿透型13例,将17例穿透型误诊为植入型(16例)或粘连型(1例),漏诊2例植入型、1例穿透型,分型诊断准确率45.95%(17/37)。结论经腹联合经阴道超声检查可显著提高产前诊断前置胎盘并胎盘植入的准确率。     

沙眼衣原体感染后热休克蛋白对妊娠的影响

妊娠期间，机体在多种应激原作用下能激活热休克蛋白(HSP)基因转录。其作用：在一定的应激强度范围内，保护胚胎，使胚胎得以存活；另一方面，当应激强度超过一定阈值，HSP则干扰胚胎的生长发育，造成病理妊娠。女性生殖道感染沙眼衣原体(CT)已成为临床常见的疾病之一，可引起一系列并发症，妊娠感染CT还可直接导致妊娠失败，对人类健康构成极大危害。本文对HSP与CT两方面的研究进展进行综述，探讨二者的关系以及对妊娠的影响和作用机制，以期为临床提供预防、诊断和治疗的理论依据。     

沙眼衣原体感染后热休克蛋白对妊娠的影响

妊娠期间,机体在多种应激原作用下能激活热休克蛋白(HSP)基因转录.其作用:在一定的应激强度范围内,保护胚胎,使胚胎得以存活;另一方面,当应激强度超过一定阈值,HSP则干扰胚胎的生长发育,造成病理妊娠.女性生殖道感染沙眼衣原体(CT)已成为临床常见的疾病之一,可引起一系列并发症,妊娠感染CT还可直接导致妊娠失败,对人类健康构成极大危害.本文对HSP与CT两方面的研究进展进行综述,探讨二者的关系以及对妊娠的影响和作用机制,以期为临床提供预防、诊断和治疗的理论依据.     

实践教学量化管理体系在临床教学中的应用

本文介绍了量化管理模式的主要内容、人员组成、具体实施及临床实习成绩考核情况,并讨论了临床医学人才应当具备的基本素质、实践教学量化管理体系建立的意义.实践证明,按照该体系要求进行实习和考评的学生优良率明显提高.评估体系考核内容全面,标准具体,指标量化,操作性强,有利于提高学生的临床技能,是一种提高教学质量的有效方法.     

左心室向心性肥厚发展与收缩功能

目的与方法:运用M型超声心动图探讨高血压病向心性肥厚程度与收缩功能的相关关系.结果:收缩功能(心率校正的FS,y轴)与向心性肥厚程度(左室重量与左室容积之比LVM/LVCV,x轴)的呈曲线相关关系,其曲线方程为y=-31.139x2+146.192x1-130.43.LVM/LVCV为2.35时,其心率校正的FS为最大41.63.结论:在心肌肥厚的初期,心肌肥厚使左心室的收缩功能起代偿性增强,当心肌增厚到一定程度时,左室收缩功能随心肌进一步肥厚而呈下降趋势.     

Effects of Atractylodes Macrocephala on the Cytomembrane Ca^2＋-activated K^＋ Currents in Cells of Human Pregnant Myometrial Smooth Muscles

The study examined the inhibitory effect of Atractylodes macrocephala(AM) on the uterine contraction during premature delivery and explored its electrophysiological mechanism by studying the effects of AM on the Ca2 -activated K currents of pregnant human myometrial smooth muscle cells with or without the treatment with interleukin-6.Single cells were acutely isolated from pregnant human myometrial smooth muscles.Whole-cell Ca2 -activated K currents were recorded by using an Axopatch1-D amplifier.The cells were divided into three groups: group A in which AM was added into perfusate,group B,in which interleukin-6 was added into perfusate) and group C in which AM was added into perfusate after addition of interleukin-6.IL-6 10 ng/mL inhibited BKca by 36.9%±13.7% as compared with control(P<0.01).AM at 2 mg/mL raised BKca by 36.7%±22.6% or 45.2%±13.7% with or without the treatment of IL-6,respectively(P<0.01).It is concluded that AM was able to enhance the BKca of pregnant human myometrial smooth muscle cells treated or un-treated with interleukin-6 and its effect on the BKca IL-treated cells was stronger that its effect on BKca of untreated cells.Our results suggested that AM can help to maintain the membrane potentials and the resting status of pregnant human myometrial smooth muscle cells.